Core C: Imaging, Molecular Biology & Nanomaterial

核心 C：成像、分子生物学

• 批准号: 10019393
• 负责人: Lei Wei
• 金额: $ 39.6万
• 依托单位: RHODE ISLAND HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-01 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10019393
• 关键词: Animal Model; Basic Science; Biomimetics; Budgets; Cells; Centers of Research Excellence; Collaborations; Communities; Consultations; Engineering; Extramural Activities; Funding; Health; Hospital Departments; Image; Investments; Laboratories; Letters; Mission; Molecular; Molecular Biology; Musculoskeletal; Nanotechnology; Orthopedics; Phase; Productivity; Research; Research Infrastructure; Research Personnel; Research Project Grants; Rhode Island; Schools; Scientist; Services; Skeletal system; Technical Expertise; Technology; Tissue Sample; Tissues; Translating; Translational Research; Update; Whole Organism; animal imaging; clinical application; human tissue; instrument; instrumentation; interest; nanomaterials; nanomedicine; novel; repaired; skeletal

Core C: Imaging, Molecular Biology & Nanomedicine Core (IMBN) 7. Project Summary/Abstract The missions of the Imaging, Molecular Biology & Nanomedicine Core (IMBN) are 1) to provide instrument, technical, and expertise services to researchers interested in skeletal health and repair, 2) to maintain state-of- art laboratories in animal imaging, molecular biology and nanomedicine supporting musculoskeletal scientists and clinicians to develop and accomplish high-quality research projects, and 3) to become a financially independent center that can continue to thrive once Phase III comes to an end. Services provided by this Core, since inception during phase I and II, have enhanced the productivity and research capabilities of skeletal system investigators and have provided a competitive advantage in garnering extramural funding. RIH has a made a significant investment in expanding its research infrastructure, as detailed in the overall center organization and management plan of this application. This has generated and sustained enormous interest in utilization of Core services that, together with significant guaranteed co-founding by RIH and Orthopedic Department, will allow sustainability of the IMBN Core during and after the Phase III funding period. We will provide the Core services as follows: 1) Provide sophisticated, state-of-the-art instrumentation in translational research, with emphasis on animal models and human tissue samples, to different projects in the COBRE, 2) Provide technical support and expert consultation in the molecular, cell, tissue, and whole organism levels to Rhode Island biomedical community - including biologists, clinicians and engineers, and 3) Provide cutting- edge nanomaterial and nanotechnology to support investigators translating basic research into clinical applications.

核心C：成像，分子生物学和纳米医学核心（IMBN） 7。项目摘要/摘要 成像，分子生物学和纳米医学核心（IMBN）的任务是1）提供仪器， 对对骨骼健康和维修感兴趣的研究人员的技术和专业知识服务，2） 动物成像，分子生物学和纳米医学的艺术实验室支持肌肉骨骼科学家 和临床医生开发和完成高质量的研究项目，以及3）成为财务上的 一旦第三阶段结束，可以继续蓬勃发展的独立中心。该核心提供的服务， 自第一阶段和II期间的成立以来，已经提高了骨骼的生产力和研究能力 系统调查人员并为获得壁外资金提供了竞争优势。 Rih有一个 在整个中心中详细介绍了扩大研究基础设施的大量投资 此应用程序的组织和管理计划。这引起了人们对 利用核心服务，以及RIH和骨科的大量保证共同创立的核心服务 部门将允许在第三阶段资金期间和之后的IMBN核心的可持续性。我们将 提供如下的核心服务：1）在翻译中提供精致的最先进的仪器 研究强调动物模型和人体组织样品，在毛cr中的不同项目中，2） 在分子，细胞，组织和整个生物水平上提供技术支持和专家咨询 罗德岛生物医学社区 - 包括生物学家，临床医生和工程师，3）提供剪裁 - 边缘纳米材料和纳米技术支持研究人员将基础研究转化为临床 申请。