Washington University Implementation Science Center for Cancer Control

华盛顿大学癌症控制实施科学中心

• 批准号: 10020381
• 负责人: Ross C Brownson
• 金额: $ 152.94万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-18 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10020381
• 关键词: Address; Advanced Malignant Neoplasm; Cancer Center; Cancer Control; Capital; Characteristics; Clinical; Communities; Complex; County; Development; Disadvantaged; Discipline; Ensure; Environment; Evidence based intervention; Fostering; Goals; Illinois; Incubators; Individual; Intervention; Investments; Laboratories; Lead; Leadership; Malignant Neoplasms; Methods; Minority; Missouri; Outcome; Population; Positioning Attribute; Provider; Public Health; Research; Research Personnel; Research Support; Resources; Rural; Science; Scientist; Sum; System; Universities; Vision; Washington; base; cancer health disparity; cancer prevention; cancer risk; career; disadvantaged population; evidence base; implementation research; implementation science; innovation; interdisciplinary collaboration; member; practice setting; synergism

PROJECT SUMMARY – Overall Component Background and vision. As an Advanced Center, the vision of the Washington University Implementation Science Center for Cancer Control (WU-ISCCC) is to conduct implementation research to help eliminate cancer disparities in rural and other disadvantaged communities. Goal. The overall goal of the WU-ISCCC is to build a rigorous, scientific evidence base for rapid-cycle implementation research to increase the reach, external validity, and sustainability of effective cancer control interventions. Our goal and Center activities capture three distinct features: (1) a focus on elimination of cancer disparities; (2) the need for rapid-cycle studies; and (3) the use of systems science approaches to enhance methods and outcomes in implementation science. Setting. Our Center will be housed in an exceptional environment that fosters transdisciplinary collaboration, catalyzes new ideas, and ensures support for research that finds solutions for complex implementation challenges in real-world settings with high cancer disparities (rural and urban counties in Missouri and Illinois). Substantial matching contributions from Washington University will allow us to strategically invest in new ideas. Aims. The specific aims of the Center are to: (1) advance the field of implementation science in cancer control by conducting innovative and impactful research; (2) expand an exceptional, diverse team of implementation science investigators and stakeholders; (3) organize and integrate Center components to facilitate transdisciplinary team science; (4) develop an Implementation Laboratory (known as the “Innovation Incubator”) to serve as a conduit for innovative, rapid-cycle, and impactful research; and (5) address cancer disparities by making it as easy as possible for disadvantaged populations to encounter, use, and benefit from evidence-based interventions. Innovations and impact. The WU-ISCCC will be innovative and provide a significant return on the scientific investment. First, our Center has distinctive features that include a combined focus on cancer disparities, the application of strategies to conduct rapid-cycle studies, and the use of systems science approaches. Second, we have assembled a diverse, world class team with strong linkages to multiple practice settings that will be critical parts of our Innovation Incubator. Third, we will engage investigators from different disciplines and invest in the development of early career scholars as cancer implementation scientists. Fourth, we will strategically and creatively disseminate products in ways that will benefit researchers, practitioners, and community members. Fifth, we have developed a focused strategy for collective integration of our projects, cores, and units to ensure that the WU-ISCCC impact is greater than the sum of its individual parts. In summary, the WU-ISCCC will be a national resource for furthering implementation science for eliminating cancer disparities.

项目摘要 - 整体组成部分 背景和视野。作为高级中心，华盛顿大学实施的愿景 癌症控制科学中心（WU-ISCCC）将进行实施研究以帮助消除 粗糙和其他灾难性社区的癌症差异。 目标。 WU-ISCCC的总体目标是为快速循环建立一个严格的科学证据基础 实施研究以提高有效癌症控制的影响力，外部有效性和可持续性 干预措施。我们的目标和中心活动捕获了三个不同的特征：（1）关注消除癌症 差异； （2）需要快速研究； （3）使用系统科学方法来增强 实施科学的方法和结果。 环境。我们的中心将安置在培养跨学科合作的特殊环境中， 催化新想法，并确保支持研究的研究，以找到复杂实施的解决方案 在癌症差异高的现实环境中（密苏里州和伊利诺伊州的农村和城市县）面临的挑战。 华盛顿大学的大量匹配贡献将使我们能够从战略上投资新想法。 目标。该中心的具体目的是：（1）推进癌症控制中实施科学领域 通过进行创新和有影响力的研究； （2）扩展一个杰出的潜水员实施团队 科学研究者和利益相关者； （3）组织和集成的中心组件以促进 跨学科团队科学； （4）开发实施实验室（称为“创新” 孵化器”）作为创新，快速周期和有影响力的研究的管道；（5）解决癌症 通过使准备灾难人群尽可能容易地遇到，使用和受益，从而差异 基于证据的干预措施。 创新和影响。 WU-ISCCC将具有创新性，并为科学提供了可观的回报 投资。首先，我们的中心具有独特的特征，包括对癌症分布的综合关注， 进行快速研究的策略以及系统科学方法的使用。第二， 我们组建了一个潜水员，世界一流的团队，与多个练习环境有很强的联系 我们创新孵化器的关键部分。第三，我们将与来自不同学科的调查员和 投资于早期职业学者作为癌症实施科学家的发展。第四，我们会的 以战略性和创造性的方式传播产品，以使研究人员，从业者和 社区成员。第五，我们制定了一种集体整合我们项目的策略， 核心和单位确保WU-ISCCC影响大于其各个部分的总和。在 摘要，WU-ISCCC将是进一步实施科学的国家资源 癌症差异。