Administrative Core

行政核心

• 批准号: 10016860
• 负责人: GEORGE S ALEXOPOULOS
• 金额: $ 72.89万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-22 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10016860
• 关键词: Address; Adult; Assessment tool; Behavior assessment; Behavioral; Collaborations; Communication; Communities; Community Integration; Community Services; Consultations; Decision Making; Depressed mood; Elderly; Ensure; Fostering; Funding; Goals; Grant; Health Technology; Healthcare; Institutes; Intervention; Leadership; Learning; Logistics; Methodology; Methods; Modeling; Monitor; Mood Disorders; National Institute of Mental Health; Neurobiology; Outcome; Pilot Projects; Process; Research; Research Domain Criteria; Research Methodology; Research Training; Resources; Structure; Targeted Research; Training; Training Programs; United States National Institutes of Health; Ursidae Family; Work; base; career development; community setting; data sharing; experience; innovation; mHealth; middle age; novel; personalized intervention; programs; recruit; synergism; therapy design; working group

ADMINISTRATIVE CORE (AC) ABSTRACT We propose a novel deployment focused model program of personalized interventions stimulated by our work with depressed older and middle-aged adults with unmet needs in settings rarely targeted by research. Our T2 interventions are informed by consumer input, developed together with community partners, and implemented by staff of community services so that they accelerate change in the real world. Drawing from RDoC, they are simplified based on neurobiology and assess engagement of behavioral targets. We use mobile health technology to augment behavioral assessment and to guide therapists in targeting their interventions. The AC will be the Center's hub and: 1. Utilize our experience in adminstering an NIMH Center over 20 years to integrate the concerns of consumers and community partners into innovative T2 studies; 2. Provide structures for scientific and logistic support, and training of staff; 3. Rely on our “know-how”, record, and explicit plans for developing sustained partnerships with community agencies and learning from them; 4. Capitalize on our methodological rigor; and 5. Bring to bear our experience in research career development. Our aims are to: 1. To develop a communication and decision-making structure that promotes synergy among consumers' and community partners' concerns, scientific aims, projects, and methods initiatives in pursuing innovative, transdisciplinary, T2 research. An executive committee (EC), consisting of consumers, community partners and specialized advisors, will organize the Center's functions with input by several Work Groups. 2. To provide guidance in identifying unmet needs of older and middle aged adults with mood disorders and access to community agencies serving them. A Community Integration Committee will assist us in this aim. 3. To offer operational support to projects in order to ensure high quality of research and to promote recruitment and collaboration. An Intervention Management Team will provide consultation on intervention design and fidelity, assessment, instrument and data sharing, recruitment, and research coordination. 4. To foster research training and career development in late- and mid-life mood disorders at Cornell and offer leadership in career development nationally. This effort will be spearheaded by a committee of leaders directing funded training programs. 5. To develop metrics and monitor the Center's progress in collaboration with the Methods Core. The Center will use the Institute for Healthcare Improvement Continuous Quality Improvement approach and set explicit milestones for its projects, and the Research Methods Core initiatives. 6. Organize a pilot project program, modeled after the NIH grant solicitation, review and monitoring process that capitalizes on the Center's resources and extends its research agenda.

行政核心 (AC) 摘要 我们提出了一个新颖的以部署为重点的模型计划，该计划是由我们的工作激发的个性化干预措施 与我们的 T2 很少针对的环境中需求未得到满足的抑郁老年人和中年人一起。 干预措施根据消费者的意见提供信息，与社区合作伙伴共同制定并实施 他们借鉴 RDoC，加速现实世界的变革。 我们根据神经生物学进行简化并评估行为目标的参与度。 增强行为评估并指导治疗师确定干预措施的技术。 AC 将成为该中心的枢纽，并且： 1. 利用我们 20 多年管理 NIMH 中心的经验 将消费者和社区合作伙伴的关注纳入创新的 T2 研究； 2. 提供 3. 依靠我们的“专业知识”、记录和明确的 与社区机构建立持续伙伴关系并向其学习的计划； 我们的方法严谨；以及 5. 发挥我们在研究职业发展方面的经验。 1. 建立促进消费者和消费者之间协同作用的沟通和决策结构 社区合作伙伴在追求创新、 跨学科的 T2 研究。执行委员会 (EC)，由消费者、社区合作伙伴组成。 和专门顾问，将根据几个工作组的意见组织中心的职能。 2. 为确定患有情绪障碍和中年人未满足的需求提供指导 社区融合委员会将协助我们实现这一目标。 3. 为项目提供运营支持，以确保高质量的研究并促进 干预管理团队将提供干预咨询。 设计和保真度、评估、仪器和数据共享、招募和研究协调。 4. 促进康奈尔大学关于晚年和中年情绪障碍的研究培训和职业发展，并提供 这项工作将由领导人委员会牵头。 指导受资助的培训计划。 5. 与方法核心中心合作制定指标并监控中心的进展。 将使用医疗保健改进研究所的持续质量改进方法并制定明确的 其项目的里程碑以及研究方法核心计划。 6. 仿照 NIH 拨款征集、审查和监测流程，组织试点项目计划 利用该中心的资源并扩展其研究议程。