Develop an ANS-based Personalized Cognitive Training for Mild Cognitive Impairment

为轻度认知障碍开发基于 ANS 的个性化认知训练

基本信息

批准号：
10704837
负责人：
Feng Vankee Lin
金额：
$ 2.26万
依托单位：
STANFORD UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-09-15 至 2023-08-31
项目状态：
已结题

项目摘要

Abstract The goal of this research diversity supplement is to enhance the impact of the parent R21/R33 by providing an early research apprentice training opportunity to a highly motivated undergraduate student, Dabne Herrera Guerra. The supplement will help her transition from a two-year community college to a four-year university and provide a research foundation for her anticipated biomedical science graduate training. Overall, the research supplement is designed to provide the candidate with critical experience in (1) clinical and neuroscience knowledge of brain aging and dementia; (2) clinical and neuroscience knowledge of cognitive training to address brain plasticity; and (3) data collection experience in assessing cognitive capacity and conducting cognitive training interventions among older adults at risk for dementia. Due to the nature of an R21/R33, we will divide the training into two phases. In alignment with the R21 stage of the parent study, the current supplement will be the 1st phase (12/2022-08/2023), focusing on gaining knowledge and hands-on experience of brain aging and dementia. Upon the awarding R33 of the parent study, we will submit the 2nd phase of the supplement (plan for 09/2023-11/2024), focusing on knowledge and hands-on experience of cognitive training and brain plasticity. The anticipated outcome of the 1st phase will be a brief topical review on differentiating brain aging within chronological vs. biological frameworks. In addition, the candidate will provide the parent study with knowledge and personal experience in working with Spanish-speaking older adults and help translate the cognitive training package developed in the parent study into a Spanish version.

抽象的这项研究多样性补充的目的是通过提供一种来增强父r21/r33的影响早期的研究学徒培训机会给一个积极进取的本科生Dabne Herrera 瓜拉。该补品将帮助她从一所两年的社区学院过渡到四年制大学，并为她预期的生物医学研究生培训提供研究基金会。总体而言，研究补充旨在为候选人提供（1）临床和神经科学方面的重要经验了解大脑衰老和痴呆症；（2）认知培训的临床和神经科学知识以解决大脑可塑性；（3）评估认知能力和进行认知的数据收集经验老年人有痴呆症风险的培训干预措施。由于R21/R33的性质，我们将分裂训练分为两个阶段。在与父母研究的R21阶段保持一致，当前的补充剂将是第一阶段（12/2022-08/2023），重点是获得大脑衰老和动手经验失智。在授予家长研究的R33后，我们将提交补充剂的第二阶段（计划 09/2023-11/2024），重点关注认知训练和大脑可塑性的知识和动手经验。第一阶段的预期结果将是关于区分大脑衰老的简短局部审查年代与生物框架。此外，候选人将为家长研究提供知识以及与讲西班牙语的老年人合作的个人经验，并有助于翻译认知培训在父母研究中开发的包装为西班牙版本。