Administrative Core

行政核心

• 批准号: 10704708
• 负责人: Timothy An-thy Chan
• 金额: $ 24.74万
• 依托单位: CLEVELAND CLINIC LERNER COM-CWRU
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-14 至 2027-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10704708
• 关键词: Accounting; Animal Experimentation; Animals; Cancer Center; Clinic; Clinical; Clinical Management; Clinical Trials; Collaborations; Combined Modality Therapy; Communication; Comprehensive Cancer Center; Core Facility; Data; Development Plans; Documentation; Education; Enrollment; Ensure; Feedback; Florida; Funding; Genomics; Goals; Grant; Human; Human Resources; Human Subject Research; Individual; Institution; Investigation; Laboratories; Leadership; Manuscripts; Monitor; Multi-Institutional Clinical Trial; Multicenter Trials; National Cancer Institute; Office of Administrative Management; Oral; Performance; Preparation; Progress Reports; Radiation; Research; Research Personnel; Resources; Schedule; Services; Site; Study Subject; System; Time; Training; Treatment Efficacy; Universities; Work; Writing; experience; human subject; innovation; meetings; operation; programs

PROJECT SUMMARY Administrative Core The Administrative Core is responsible for the overall leadership, management, and execution of the ROBIN center, and it will provide overall organizational, administrative, scientific and clinical management. The Administrative Core will oversee and coordinate all ROBIN program components and centrally monitor and evaluate their performance. In addition, the Administrative Core will facilitate all interactions with the External Advisory Board (EAB), the Steering Committee, and the other sites of the national ROBIN program. This ROBIN center involves 3 institutions (Cleveland Clinic, Emory University, and Case Western Reserve University), with multiple enrollment sites (Cleveland Clinic system, Cleveland Clinic Florida system, Emory University system) across 2 NCI-designated Comprehensive Cancer Centers (Case Comprehensive Cancer Center, Emory Cancer Center), with representation across these institutions as project and core leaders. The Administrative Core personnel will be led by Drs. Chan, Yu, and Scott, with collaboration from the trial and project leads. Both Drs. Chan and Yu (ROBIN PIs) have extensive experience in managing multi-institution clinical trial and laboratory-based research programs. The specific aims for the Administrative Core are as follows. In Aim 1, the Core will provide all organizational, administrative, educational, and scientific coordination for the ROBIN center projects and cores by cultivating and promoting the ROBIN team through innovation and excellence, collaboration, leveraging resources, and providing constructive feedback. In Aim 2, the Core will provide centralized administrative management for all fiscal aspects of the ROBIN center, including but not limited to clinical trial execution, accounting of grant funds, progress reports, communication, meeting scheduling and minutes, and manuscript and grant preparation. In Aim 3, the Core will evaluate research progress through oral and written documentation, with regular input from the EAB, Steering Committee, and National Cancer Institute (NCI) leadership to ensure that each project meets its objectives within the proposed time frame and to facilitate interactions with other ROBIN sites for trans-ROBIN center projects. In Aim 4, the Core will ensure integration across ROBIN components, including projects and cores, across all sites, and provide interaction through scientific exchanges, coordination of an annual scientific retreat, and through training and development plans that will ensure state-of-the-art practices. In Aim 5, the Core will ensure and monitor best practices for human subjects and animal research for all ROBIN center projects and cores as well as clinical and data operations, and to ensure adequate human and animal biospecimens for all projects (with the Translational and Clinical Correlates Core).

项目概要 行政核心 行政核心负责全院的全面领导、管理和执行。 ROBIN中心，它将提供全面的组织、行政、科学和临床管理。这 行政核心将监督和协调所有 ROBIN 计划组成部分，并集中监控和 评估他们的表现。此外，行政核心将促进与外部的所有互动 咨询委员会 (EAB)、指导委员会以及国家 ROBIN 计划的其他场所。这 ROBIN中心涉及3家机构（克利夫兰诊所、埃默里大学、凯斯西储大学） 大学），拥有多个招生地点（克利夫兰诊所系统、克利夫兰诊所佛罗里达系统、埃默里大学 大学系统）横跨 2 个 NCI 指定的综合癌症中心（病例综合癌症中心） 中心、埃默里癌症中心），在这些机构中担任项目和核心领导者。这 行政核心人员将由博士领导。 Chan、Yu 和 Scott 在试验和 项目领导。两位博士。 Chan 和 Yu（ROBIN PI）在管理多机构方面拥有丰富的经验 临床试验和基于实验室的研究计划。行政核心的具体目标如下 接下来。在目标 1 中，核心将提供所有组织、行政、教育和科学 通过培养和提升ROBIN团队来协调ROBIN中心项目和核心 创新和卓越、协作、利用资源并提供建设性反馈。 在目标 2 中，核心将为 ROBIN 的所有财务方面提供集中行政管理 中心，包括但不限于临床试验执行、拨款资金会计、进度报告、 沟通、会议安排和会议记录、手稿和拨款准备。在目标 3 中，核心 将通过口头和书面文件评估研究进展，并定期听取 EAB 的意见， 指导委员会和国家癌症研究所 (NCI) 领导层确保每个项目符合其要求 在建议的时间范围内实现目标，并促进与其他 ROBIN 站点的交互以实现跨 ROBIN 中心项目。在目标 4 中，核心将确保 ROBIN 组件之间的集成，包括项目和 跨所有站点的核心，并通过科学交流、年度科学会议的协调来提供互动 务虚会，并通过培训和发展计划确保最先进的实践。在目标 5 中， Core 将确保和监控所有 ROBIN 中心的人类受试者和动物研究的最佳实践 项目和核心以及临床和数据操作，并确保足够的人力和动物 所有项目的生物样本（具有转化和临床相关核心）。