Core N: Biostatistics and Modeling

核心 N：生物统计学和建模

• 批准号: 10396500
• 负责人: SONIA JAIN
• 金额: $ 16.45万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-04-01 至 2023-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10396500
• 关键词: Acquired Immunodeficiency Syndrome; Area; Award; Bioinformatics; Biometry; Biostatistics Core; Caring; Collaborations; Consultations; Development; Disease; Doctor of Philosophy; Economic Models; Epidemic; Grant; HIV; Information Technology; Institutes; Institution; Leadership; Mentors; Methodology; Methods; Mission; Modeling; NIH Office of AIDS Research; Pathogenesis; Price; Process; Publications; Research; Research Personnel; Research Priority; Research Support; Research Training; Resource Sharing; Science; Services; Statistical Methods; Strategic Planning; Techniques; Technology; Time; Training; Training Activity; United States National Institutes of Health; Vaccines; career development; clinical investigation; design; economic evaluation; health disparity; health economics; infectious disease model; innovation; mathematical model; next generation; novel; research and development

Project Summary/Abstract Core N - The mission of the San Diego Center for AIDS Research (SD CFAR) Biostatistics and Modeling (BAM) Core is to provide quantitative expertise, collaboration, and training in the areas of biostatistics and infectious disease modeling related to HIV research. In accordance with NIH OAR priorities and our CFAR’s focus, we prioritize research in optimizing HIV care, alleviating HIV health disparities, and advancing discovery in HIV cure and vaccines. The BAM Core’s services are critical to our CFAR, as other quantitative shared resources across our institutions are generally not tailored to HIV research or focused on supporting emerging HIV investigators. Following a strategic planning process in 2016, the BAM Core was established in June 2016 as part of a restructuring of the Clinical Investigation (CI) Core and closure of the Bioinformatics and Information Technology (BIT) Core. Since its inception in June 2016, the BAM Core has provided support to 47 users (64% emerging), and 18 NIH-supported grants and supplements from 6 NIH institutes. In this short time, the BAM Core has been cited by 28 publications. The BAM Core is composed of two inter-connected units. The Biostatistics Unit handles statistical requests including pre-award statistical support and post-award collaboration. The Modeling Unit supports research involving HIV epidemic and pathogenesis modeling and health economic evaluation including pre-award support and post-award collaboration. Additionally, both units incorporate a particular focus on methodological innovation and training/mentoring in quantitative methods. The BAM Core aims are: (1) To support clinical investigation and translational HIV research by providing rigorous quantitative biostatistics support and services (Biostatistics Unit). (2) To enhance the impact of CFAR research by providing project guidance and high-level expertise on HIV infectious disease and economic modeling (Modeling Unit). (3) To encourage, mentor, and train the next generation of HIV investigators in biostatistics and modeling methodologies.

项目摘要/摘要 核心N-圣地亚哥艾滋病研究中心（SD CFAR）生物统计学和建模的任务 （BAM）核心是在生物统计学领域提供定量专业知识，协作和培训 与HIV研究有关的传染病模型。根据NIH的优先事项和我们的CFAR 重点，我们优先考虑优化艾滋病毒护理，减轻艾滋病毒健康差异并提高发现的研究 在HIV治疗和疫苗中。 BAM Core的服务对我们的CFAR至关重要，因为其他定量性共享 我们机构中的资源通常不适合艾滋病毒研究，也不是专注于支持新兴的 艾滋病毒调查人员。 在2016年的战略规划过程之后，BAM核心于2016年6月成立 临床研究（CI）核心的重组和生物信息学和信息的关闭 技术（位）核心。自2016年6月成立以来，BAM Core为47位用户提供了支持（64％ 新兴）和18家NIH研究所的NIH支持和补充。在这个短时间内，BAM 核心已被28个出版物引用。 BAM芯由两个相互连接的单元组成。生物统计局处理统计请求 包括备受授权的统计支持和宣布后的合作。建模单元支持研究 涉及艾滋病毒的流行和发病机理建模和健康经济评估，包括预先归功于 支持和雄辩后的合作。此外，这两个单元都融合了对方法论的特别关注 定量方法的创新和培训/指导。 BAM核心目的是：（1）通过提供临床调查和转化HIV研究 严格的定量生物统计学支持和服务（生物统计学单元）。 （2）增强CFAR的影响 通过在HIV传染病和经济上提供项目指导和高级专业知识来进行研究 建模（建模单元）。 （3）鼓励，心理和培训下一代的艾滋病毒调查员 生物统计学和建模方法。