UC Davis Training Program in Chemical Biology

加州大学戴维斯分校化学生物学培训计划

• 批准号: 9306883
• 负责人: PETER A. BEAL
• 金额: $ 15.59万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-01 至 2020-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9306883
• 关键词: Biology; Chemicals; Training Programs

 DESCRIPTION (provided by applicant): The goal of the UC Davis Chemical Biology Program (CBP) is to provide effective cross training at the chemistry/biology interface for pre-doctoral candidates. After their CBP cross training, these students will understand the value of the synthesis and analysis tools traditionally associated with chemistry in addressing problems related to biological pathways, cells, tissues and organisms with a particular focus on biological questions related to human health. The chemical biology community at UC Davis includes a large group of productive, well-funded and collaborative faculty members with a strong history of mentoring pre-doctoral students. The CBP faculty comprises 29 trainers with primary appointments in six different departments in five different colleges. CBP faculty research programs cover a broad swath of topics (e.g. calcium signaling, glycobiology, metabolic engineering, DNA repair, RNA modification, translation, photoreception, photosynthesis, cancer therapeutics, drug metabolism, metabolomics, molecular imaging and genome editing) using an extensive range of approaches (e.g. genetics, genomics, x-ray crystallography, NMR spectroscopy, EPR spectroscopy, mass spectrometry, combinatorial chemistry, high throughput screening, computational modeling, enzymology and organic synthesis). Trainees will be selected for this program from the top first year students with an expressed interest in carrying out thesis research at the chemistry/biology interface from five different graduate groups (Chemistry; Biochemistry, Molecular, Cellular and Developmental Biology; Biomedical Engineering; Pharmacology and Toxicology and Biophysics). These students will engage in cross training coursework, cross training laboratory rotations, research-in-progress presentations, career development activities, responsible conduct in research training and annual retreats. This proposal requests support for eight predoctoral student slots to support 4-5 trainees for two years each, typically during the second and third years of their PhD training. This support, along with the major institutional commitments made by UC Davis, will establish a predoctoral program that will more effectively prepare our trainees for scientific careers at the chemistry/biology interface.

 描述（由适用提供）：UC Davis化学生物学计划（CBP）的目的是在化学/生物学界面为博士前候选者提供有效的交叉训练。经过CBP的交叉训练，这些学生将了解与化学有关的合成和分析工具的价值，这些工具在解决与生物途径，细胞，组织和组织有关的问题方面，特别关注与人类健康有关的生物学问题。加州大学戴维斯分校的化学生物学社区包括一大批产品，资金丰富且合作的教职员工，具有悠久的心理前学生历史。 CBP教职员工由29名培训师组成，在五个不同学院的六个不同部门任命。 CBP faculty research programs cover a broad swath of topics (e.g. calcium signaling, glycobiology, metabolic engineering, DNA repair, RNA modification, translation, photoreception, photosynthesis, cancer therapy, drug metabolism, metabolomics, molecular imaging and genome editing) using an extensive range of approaches (e.g. genetics, genomics, x-ray crystallography, NMR光谱，EPR光谱，质谱法，组合化学，高吞吐量筛选，计算建模，酶学和有机合成）。将从五个不同的研究生组（化学；生物化学，分子，细胞和发育生物学；生物医学工程；药理学，毒理学和毒理学和生物物理学）的化学/生物学界面中，从高级一年级学生中选出该计划的学员。这些学生将参加跨培训课程，跨培训实验室轮换，进行研究的演讲，职业发展活动，研究培训中的负责任和年度务虚会。该提案要求支持八个学生老虎机，以支持4-5名学员两年，通常在其博士学位培训的第二年和第三年。这种支持以及加州大学戴维斯分校做出的重大机构承诺将建立一项专业计划，将更有效地为我们的学员在化学/生物学界面上的科学职业做好准备。