2023 RNA Editing Gordon Research Conference and Gordon Research Seminar

2023年RNA编辑戈登研究大会暨戈登研究研讨会

• 批准号: 10683612
• 负责人: PETER A. BEAL
• 金额: $ 0.95万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-03-15 至 2024-03-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10683612
• 关键词: Asia; Autoimmune Diseases; Biochemistry; Biological Models; Biological Process; Canada; Cellular biology; Chemicals; Cognition; Collaborations; Cytosine; DNA; DNA Modification Process; Data; Deaminase; Dedications; Defect; Detection; Development; Engineering; Enzymes; Epigenetic Process; Europe; Faculty; Female; Fostering; Gene Expression; Genes; Genetic Diseases; Goals; Health; Health Sciences; Hour; Human; Industry; International; Knowledge; Malignant Neoplasms; Mentorship; Modification; Natural Immunity; Notification; Nucleic Acids; Nucleosides; Postdoctoral Fellow; Protein Biosynthesis; RNA; RNA Editing; Renaissance; Research; Research Personnel; Rest; Saskatchewan; Science; Scientist; Student Selections; Surveys; Techniques; Texas; Therapeutic; Transfer RNA; Universities; Uracil; Woman; adaptive immunity; base; base editor; biological systems; career; epitranscriptomics; gender equity; genome editing; graduate student; human disease; meetings; next generation; nucleobase; posters; symposium; Asia; Autoimmune Diseases; Biochemistry; Biological Models; Biological Process; Canada; Cellular biology; Chemicals; Cognition; Collaborations; Cytosine; DNA; DNA Modification Process; Data; Deaminase; Dedications; Defect; Detection; Development; Engineering; Enzymes; Epigenetic Process; Europe; Faculty; Female; Fostering; Gene Expression; Genes; Genetic Diseases; Goals; Health; Health Sciences; Hour; Human; Industry; International; Knowledge; Malignant Neoplasms; Mentorship; Modification; Natural Immunity; Notification; Nucleic Acids; Nucleosides; Postdoctoral Fellow; Protein Biosynthesis; RNA; RNA Editing; Renaissance; Research; Research Personnel; Rest; Saskatchewan; Science; Scientist; Student Selections; Surveys; Techniques; Texas; Therapeutic; Transfer RNA; Universities; Uracil; Woman; adaptive immunity; base; base editor; biological systems; career; epitranscriptomics; gender equity; genome editing; graduate student; human disease; meetings; next generation; nucleobase; posters; symposium

Project Summary The GRC on RNA editing is the premier international meeting dedicated to nucleic acid modifications. The 2023 meeting is subtitled: “RNA/DNA editing and epitranscriptomics across biological systems”. Modifications to the common nucleosides found in DNA and RNA have been known for many years. However, recent advances in analytical techniques for their detection, along with a deeper understanding of the broad impact these modifications have on fundamental biological processes, including human disease, have caused a renaissance in their study. Indeed, we now know that nucleic acid modifications are common in various naturally occurring nucleic acids and influence gene expression, protein synthesis, cognition, innate and adaptive immunity, autoimmune disease and cancer. Furthermore, several research labs have repurposed enzymes that naturally edit RNA or modify DNA bases for targeted genome editing. This meeting will bring together a diverse group of scientists with varying expertise with the common goal of sharing ideas and approaches that can advance our understanding of the many facets of nucleic acid modifications. This conference has three specific aims. First, we will support the development of the next generation of scientific leaders. Key to achieving this aim is supporting the accompanying Gordon Research Seminar (GRS). In the two days preceding the GRC, a GRS will take place that is focused on the exchange of research data and ideas among graduate students and post-docs in the editing and modification field. Our second specific aim is to facilitate knowledge exchange on DNA and RNA editing and modification. During the five day GRC, there is approximately four hours in each afternoon for networking, there are four poster sessions, 46 speakers and 6 speakers selected from abstracts covering all aspects of DNA and RNA editing research to foster interdisciplinary and collaborative interactions. Our third aim is to connect academic researchers to stakeholders in industry. Representatives of gene editing companies and biomedical science companies with an editing/modification focus will participate in the 2023 conference. This interaction will facilitate collaboration with companies or other labs that can take basic health related research to the next level of developing treatments for genetic diseases.

项目摘要 RNA编辑的GRC是致力于修改核酸的首屈一指的国际会议。这 2023会议的副标题为“生物系统跨生物系统的RNA/DNA编辑和同意组合”。修改 在DNA和RNA中发现的常见核苷已有多年了。但是，最近 分析技术的检测进步，以及对广泛影响的更深入的了解 这些修改对包括人类疾病在内的基本生物过程已经引起了 文艺复兴时期的研究。确实，我们现在知道核酸修饰在各种中很常见 天然存在的核酸并影响基因表达，蛋白质合成，认知，先天和 适应性免疫学，自身免疫性疾病和癌症。此外，一些研究实验室已重新利用 自然编辑RNA或修饰DNA碱基的酶进行靶向基因组编辑。这次会议将带来 一群具有不同专业知识的科学家团体，其共同目标是分享思想和 可以提高我们对核酸修饰的许多方面的理解的方法。这 会议有三个具体的目标。首先，我们将支持下一代科学的发展 领导者。实现此目标的关键是支持参与的戈登研究研讨会（GRS）。在 GRC之前的两天，将进行GRS，重点是交换研究数据和 在编辑和修改领域的研究生和邮政研究生的想法。我们的第二个具体目标是 促进知识交换以及RNA编辑和修饰。在五天的GRC中，有 每天大约需要四个小时的网络，有四个海报会议，46个扬声器和6个 从摘要中选出的演讲者涵盖了DNA和RNA编辑研究的各个方面以促进 跨学科和协作互动。我们的第三个目标是将学术研究人员与 工业利益相关者。基因编辑公司和生物医学科学公司的代表 编辑/修改重点将参加2023会议。这种互动将有助于合作 与公司或其他可以将基本与健康相关的研究纳入新的开发水平的公司或其他实验室 遗传疾病的治疗方法。