Reducing Methamphetamine Use and HIV Sex-risk Behaviors in Out-of-Treatment MSM

减少未治疗男男性接触者中甲基苯丙胺的使用和艾滋病毒性风险行为

• 批准号: 7223075
• 负责人: Cathy J Reback
• 金额: $ 21.83万
• 依托单位: VAN NESS RECOVERY HOUSE
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-30 至 2008-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7223075
• 关键词: AIDS education /prevention; Internet; behavioral /social science research tag; clinical research; counseling; early /brief intervention /therapy; health services research tag; high risk behavior /lifestyle; homosexuals; human subject; human therapy evaluation; male; methamphetamine; therapy design /development

DESCRIPTION (provided by applicant): Methamphetamine (meth) use is significantly associated with HIV infection among men who have sex with men (MSM), predominantly through high-risk sexual behaviors that are facilitated by use of the drug. This research study will enroll 72 out-of-treatment, meth-using MSM into a novel information technology (IT) communication intervention, i.e., Project Tech Support. Over the course of two weeks, participants will be asked to engage in a variety of communication technologies (e.g., text messaging, emails, instant messaging) to receive real-time HIV prevention messages, social support and referrals for healthier, pro-social choices regarding drug- and sexual-risk behaviors. All IT communications will be based on the theoretical framework of the study design. The study aims to (1) conduct formative work to assist the development of an IT communication intervention for reducing meth use and high-risk sexual behaviors among out-of-treatment MSM; (2) assess the feasibility and utility of the behavioral intervention on the target population; and (3) gather indicators of the mechanism of action for this intervention, a dose-response association will be evaluated between the extent of use of IT communication system and the degree of education in meth use and concomitant sexual risk behaviors. We hypothesize that (1) brief interventions that target reductions in meth use and concomitant sexual risk behaviors in MSM can be delivered successfully using text messaging, Internet resources and other IT communication; and (2) there will be a dose-response association in IT communication, thus, the more an MSM interacts with the IT communication, the less likely he is to engage in high rates of meth use and sexual risk behaviors. Data from the formative phase will guide development of the intervention, which, in turn, will be evaluated for feasibility and utility. Evaluations, including biological markers for drug use, HIV serostatus, and STIs, will be collected at baseline, two-week and three-month follow-up. Cognitive and behavioral outcomes will be measured. This brief intervention builds upon the strengths of behavioral science and is designed to assist out-of-treatment, meth-using MSM reduce drug use and HIV transmission behaviors. Findings from this study will inform the field on the feasibility of adapting an IT communication intervention for reducing sexual risk behaviors and HIV acquisition and transmission among out-of-treatment, meth-using MSM.

描述（由申请人提供）：甲基苯丙胺（meth）的使用与男男性接触者（MSM）的艾滋病毒感染显着相关，主要是通过使用该药物促进的高风险性行为。这项研究将招募 72 名未接受治疗、使用冰毒的 MSM 参与一项新型信息技术 (IT) 沟通干预措施，即项目技术支持。在两周的时间里，参与者将被要求使用各种通信技术（例如短信、电子邮件、即时消息）来接收实时艾滋病毒预防信息、社会支持和推荐，以做出更健康、亲社会的选择关于毒品和性风险行为。所有IT交流都将基于研究设计的理论框架。该研究的目的是 (1) 开展形成性工作，协助制定 IT 沟通干预措施，以减少未接受治疗的 MSM 中的冰毒使用和高风险性行为； （2）评估行为干预对目标人群的可行性和效用； (3) 收集该干预措施的作用机制指标，将评估信息技术通信系统的使用程度与冰毒使用和伴随性危险行为的教育程度之间的剂量反应关联。我们假设 (1) 可以使用短信、互联网资源和其他 IT 通信成功地实施旨在减少 MSM 中冰毒使用和伴随的性危险行为的简短干预措施； (2)信息技术交流中存在剂量反应关联，因此，MSM与信息技术交流互动越多，他从事冰毒使用率和性危险行为的可能性就越小。形成阶段的数据将指导干预措施的制定，进而评估干预措施的可行性和实用性。将在基线、两周和三个月的随访时收集评估结果，包括药物使用的生物标志物、艾滋病毒血清状态和性传播感染。将测量认知和行为结果。这项简短的干预措施建立在行为科学的优势之上，旨在帮助未接受治疗、使用冰毒的 MSM 减少吸毒和艾滋病毒传播行为。这项研究的结果将为该领域提供信息技术通信干预措施的可行性，以减少未接受治疗、使用冰毒的 MSM 中的性危险行为以及艾滋病毒的感染和传播。