BSL-3 Practices Core

BSL-3 实践核心

• 批准号: 10793950
• 负责人: JOSEPH A. KANABROCKI
• 金额: $ 60.4万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-18 至 2028-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10793950
• 关键词: Address; Animals; Area; Attention; Awareness; Biocompatible Materials; Biological; Biological Products; Biomedical Research; Categories; Chicago; Communicable Diseases; Communication Tools; Communities; Competence; Containment of Biohazards; Coordination and Collaboration; Dangerousness; Decontamination; Development; Discipline; Disease; Education; Educational Curriculum; Elements; Emergency response; Emerging Communicable Diseases; Engineering; Ensure; Environment; Equipment; Equipment and supply inventories; Family; Goals; Human; Human Resources; Individual; Infectious Diseases Research; Infrastructure; Laboratories; Laboratory Research; Maintenance; Mentors; Mission; National Institute of Allergy and Infectious Disease; Pathogenicity; Procedures; Program Description; Property; Recommendation; Research; Research Personnel; Resources; Risk; Risk Assessment; Safety; Scientist; Secure; Services; System; Toxin; Training; Training Programs; Training and Education; United States; Universities; Update; Work; biocontainment facility; biodefense; biosecurity; design; experience; hazard; investigator training; meetings; member; microorganism; operation; pathogen; personal protective equipment; programs; skills; synergism

PROJECT ABSTRACT (Core 2/C2BSL3@HTRL) The University of Chicago Howard T. Ricketts Biocontainment Laboratory is proposing the establishment of a A/BSL-3 Practices Core, C2BSL3@HTRL, to provide comprehensive training and mentoring in the safe use of pathogenic microorganisms, toxins, and Select Agents. The curriculum covers topics such as biosecurity, risk assessment, biohazard containment, safe handling of pathogens, decontamination, and emergency response plans. The core will develop and maintain Standard Operating Procedures (SOPs) and provide training for personnel working in the A/BSL-3 space and associated building systems. This core will employ an integrated approach to Biosafety education by strategically coordinating and synergizing the educational experiences for research investigators and support staff, Biosafety professionals, and biocontainment facility engineers. Elements of the training provided by C2BSL3@HTRL include the following:  Annual HTRL Training: This training covers all aspects of biosafety, including the properties of biological agents, risk assessment, personal protective equipment, decontamination, and emergency response plans and is given to all members of the HTRL team.  HTRL Hands-On (one-on-one) Training and Mentoring: This one-on-one training program ensures everyone receives personalized attention and training to address their specific needs, skills, and competencies to work successfully and safely in A/BSL3.  HTRL Monthly Training: The monthly training serves as a vital communication tool for updating all facility users on various aspects of the laboratory. The meeting provides training on future research areas and addresses any concerns or questions that users may have, which promotes collaboration and coordination among all HTRL users.  Aerobiology Maintenance and Training: The aerobiology core provides training on the unique challenges, design, setup, and safe practices of aerobiology and use of the Class III Biosafety Cabinet.  Development of Select Agent SOPs and Inventory: This program describes the development of SOPs and training on inventory reconciliation for all Select Agents and RG3 pathogens.

项目摘要（Core 2/C2BSL3@HTRL） 芝加哥大学霍华德·T·里基茨生物卫生实验室正在提议建立 A/BSL-3实践核心，C2BSL3@HTRL，可在安全使用方面提供全面的培训和心理 致病性微生物，毒素和选择剂。该课程涵盖了生物安全，风险等主题 评估，生物危害遏制，病原体的安全处理，净化和应急响应 计划。核心将制定和维护标准操作程序（SOP），并为 在A/BSL-3空间和相关建筑系统中工作的人员。该核心将雇用整合 通过战略性地协调并协同教育经验来实现生物安全教育的方法 研究调查人员和支持人员，生物安全专业人员和生物培养设施工程师。 C2BSL3@HTRL提供的培训元素包括以下内容： 年度HTRL培训：此培训涵盖了生物安全的各个方面，包括 生物制剂，风险评估，个人保护设备，去污和紧急情况 响应计划，并给予HTRL团队的所有成员。 HTRL动手（一对一）培训和指导：此一对一培训计划可确保 每个人都接受个性化的关注和培训，以满足他们的特定需求，技能和 在A/BSL3中成功，安全地工作的能力。 HTRL月度培训：每月培训是更新所有内容的重要交流工具 设施使用者在实验室的各个方面。会议提供有关未来研究领域的培训 并解决用户可能遇到的任何问题或问题，这促进了协作和 所有HTRL用户之间的协调。 经营生物学维护和培训：环境生物学核心提供有关独特的培训 挑战，设计，设置和安全的经营生物学和使用III级生物安全柜的使用。 开发选择代理SOP和库存：此程序描述了SOP的开发 以及所有精选药物和RG3病原体的库存对帐培训。