Core C1: Data Interpretation Core

核心 C1：数据解释核心

基本信息

批准号：
7924080
负责人：
RONALD GARY TOMPKINS
金额：
$ 77.72万
依托单位：
MASSACHUSETTS GENERAL HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2001
资助国家：
美国
起止时间：
2001-09-30 至
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/7924080
关键词：
Advisory Committees Algorithms Analysis of Variance Area Arts Astronomy Basic Science Bayesian Analysis Behavior Bioconductor Bioinformatics Biological Biological Markers Biometry Biostatistical Methods Biostatistics Core Books Burn Trauma Burn injury CD4 Positive T Lymphocytes Cell Communication Cells Chairperson Classification Clinical Clinical Data Clinical Research Collaborations Communication Communities Complement component C1s Complex Complex Genetic Trait Computational Biology Computer Analysis Computer software Computers Critical Illness Data Data Analyses Data Quality Data Set Databases Decision Theory Derivation procedure Detection Development Diagnosis Digestion Disease Employee Strikes Ensure Environment Equation Experimental Designs Florida Focus Groups Fourier transform ion cyclotron resonance Functional disorder Funding Gene Cluster Gene Expression Gene Proteins Generations Genes Genetic Genome Genomics Goals Grant Graph Health Human Human Biology Immune Immune response Inflammation Inflammatory Information Theory Institution Internet Investigation Knowledge Label Literature Machine Learning Mass Spectrum Analysis Measurement Measures Medical Medical Imaging Metabolic Methodology Methods Microarray Analysis Microbiology Modeling Molecular Genetics Molecular Models Molecular Profiling Multivariate Analysis Noise Oligonucleotide Microarrays Online Systems Ontology Operative Surgical Procedures Outcome Participant Pathologic Pathway Analysis Pathway interactions Patients Pattern Peptides Performance Physiological Plasma Plasma Proteins Policy Research Postdoctoral Fellow Principal Investigator Procedures Process Progress Reports Proteins Proteome Proteomics Protocols documentation Publications Quality Control Regression Analysis Regulation Research Research Personnel Resources Sampling Schedule Science Scientist Sequence Analysis Services Signal Transduction Site Statistical Methods Structure Survival Analysis System Systems Biology Technology Textbooks Time Transcriptional Regulation Trauma Trypsin United States National Academy of Sciences Universities Validation Washington Wing Work base cDNA Arrays clinical phenotype comparative genomic hybridization computerized data processing data format data integration data mining design forest gene function genetic linkage analysis genome wide association study genome-wide immune function injured interest knowledge base meetings member molecular modeling monocyte multicore processor multidisciplinary novel novel strategies open source patient oriented professor programs protein expression research study response response to injury statistics success symposium theories tool

项目摘要

The Data Interpretation Core (DIG) performs computational genomics and proteomics analyses, conducts statistical and pathway data analysis for gene expression microarray and high throughput mass spectrometric proteomics, and develops tools for data computation and modeling. This Core serves as a tool for integrative analysis of the comprehensive human genomic and proteomic data generated by the Program. Information from this Core helps correlate gene expression and protein patterns with the immuno-inflammatory phenotypes and clinical trajectories of injured patients.

数据解释核心 (DIG) 执行计算基因组学和蛋白质组学分析，进行基因表达微阵列和高通量质谱的统计和通路数据分析蛋白质组学，并开发数据计算和建模工具。该核心作为集成工具分析该计划生成的全面人类基因组和蛋白质组数据。信息该核心有助于将基因表达和蛋白质模式与免疫炎症表型相关联以及受伤患者的临床轨迹。