Data Resource Core

数据资源核心

• 批准号: 10708016
• 负责人: Adam Cain Resnick
• 金额: $ 120.49万
• 依托单位: CHILDREN'S HOSP OF PHILADELPHIA
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-26 至 2025-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10708016
• 关键词: Acceleration; Address; Adoption; Artificial Intelligence; Authorization documentation; Automation; Automobile Driving; Big Data; Binding; Child; Childhood; Clinical; Clinical Data; Communities; Computer software; Data; Data Analyses; Data Scientist; Data Set; Databases; Development; Disease; Family member; Fast Healthcare Interoperability Resources; Feedback; Foundations; Future; Genes; Genetic Predisposition to Disease; Growth; Infrastructure; Language; Leadership; Life Cycle Stages; Machine Learning; Maintenance; Malignant Childhood Neoplasm; Malignant Neoplasms; Metadata; Monitor; Patients; Pattern; Research; Research Personnel; Resources; Secure; Services; Structural Congenital Anomalies; Sustainable Development; Techniques; Technology; Time; Trust; United States National Institutes of Health; Variant; Work; analytical tool; authority; cloud based; cloud platform; cohort; cost; data access; data interoperability; data management; data portal; data resource; database of Genotypes and Phenotypes; design; empowerment; genomic data; improved; innovation; interoperability; light weight; open data; open source; programs; support tools; tool; virtual

PROJECT SUMMARY The Kids First Data Resource Core (DRC) provides the community facing portal, cloud-based workspace (CAVATICA), and analytic tools that support analysis and scientific discovery utilizing Kids First Data as provisioned by the Kids First Data Coordinating Core (DCC). The aims of this project expand and improve upon the existing Kids First Data Portal Core to provide a wider scope of data resources to the community to support analysis and scientific discovery. The Kids First Portal provides researchers, clinicians, data scientists, patients, and their family members with a fully functional database to explore, build virtual cohorts, and analyze clinical and genomic data. As part of this project, the portal will be expanded to include advanced cohort building and search capabilities, including genes and variants as well as new analytic capabilities. The portal and CAVATICA will have new integrations, such as the variant workbench and deployment of lightweight scientific applications to better empower a wide range of users. The DRC will also work towards understanding new and emerging opportunities to support artificial intelligence and machine learning (AI/ML) techniques and workflows. To enable the broadest use of Kids First data, the DRC is committed to interoperability and will leverage standards such as GA4GH DRS, NIH Research Auth Service, Common Workflow Language, FHIR and other emerging standards across the NIH data landscape.

项目摘要 孩子们的第一个数据资源核心（DRC）提供了面向门户的基于云的工作区的社区 （cavatica）以及支持分析和科学发现的分析工具，利用孩子的第一个数据作为 由孩子们的第一个数据协调核心（DCC）提供。该项目的目的扩展和改进 现有的孩子首先数据门户核心为社区提供更广泛的数据资源范围以支持 分析和科学发现。儿童第一门户提供研究人员，临床医生，数据科学家，患者， 他们的家人拥有功能齐全的数据库，以探索，建立虚拟队列和分析临床 和基因组数据。作为该项目的一部分，门户将扩展到包括高级队列大楼和 搜索功能，包括基因和变体以及新的分析功能。门户和卡瓦蒂加 将具有新的集成，例如变体工作台和轻型科学应用的部署 更好地授权广泛的用户。刚果民主共和国还将致力于理解新的和新兴 支持人工智能和机器学习（AI/ML）技术和工作流程的机会。启用 刚果民主共和国最广泛使用的儿童最初数据使用了互操作性，并将利用标准（例如 GA4GH DR，NIH研究授课服务，通用工作流语言，FHIR和其他新兴标准 跨NIH数据格局。