Core 1 Biostatistics

核心 1 生物统计学

基本信息

批准号：
10693884
负责人：
Kouros Owzar
金额：
$ 11.12万
依托单位：
DUKE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2005
资助国家：
美国
起止时间：
2005-09-01 至 2025-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10693884
关键词：
Address Adherence Algorithms Area Awareness Basic Science Bioinformatics Biomedical Research Biometry Biostatistics Core Clinical Clinical Data Clinical Sciences Collaborations Communities Computer software Conceptions Data Data Collection Data Provenance Development Discriminant Analysis Documentation Education Ensure Experimental Designs Faculty Flow Cytometry Grant Human Resources Information Dissemination Laboratories Leadership Licensing Malignant Neoplasms Medical center Methodology Methods Mission Molecular Analysis Performance Phase Procedures Program Research Project Grants Proteomics Quality Control Radiation Reporting Reproducibility Research Research Design Research Personnel Research Project Grants Research Support Resources Role Science Statistical Computing Statistical Data Interpretation Statistical Methods Technical Expertise Testing Translational Research Validation candidate marker computerized tools design experience experimental study genomic data improved literate medical countermeasure member next generation sequencing novel programs prospective radiation countermeasure scientific computing skills sound statistical learning statistics tool translational cancer research

项目摘要

The continuing mission of the RadCCORE Biostatistics Core is to provide applied and theoretical biostatistics and bioinformatics expertise in support of the continued scientific mission of this grant. To this end, the core will serve as a centralized resource for expertise in applied and theoretical cancer biostatistics as well as data and scientific computing. The core faculty and staff will bring to bear not only technical expertise but also their vast experience in and passion for basic, clinical and translational cancer research to help to drive the science. The core personnel will be involved in every facet of the proposed research starting from the conception stage of studies and experiments through the interpretation and dissemination of the resulting findings. The core personnel will collaborate pro-actively with clinical and lab personnel of this project to ensure that studies and experiments are set up and executed optimally. The scope of scientific discovery and rigor should neither be limited nor compromised due to lack of appropriate and adequate statistical methodology or computational tools. When needed and appropriate, the core personnel will extend existing methods or develop novel statistical methods or computational tools to enable the investigators of this project address scientific questions with rigor and efficiency. The core will also provide ongoing education in the area of statistical methodology and concept to the project investigators.

Radccore生物统计学核心的持续任务是提供应用和理论生物统计学以及生物信息学专业知识，以支持这笔赠款的持续科学任务。为此，核心将充当用于应用和理论癌症生物统计学以及数据和数据的专业知识的集中资源科学计算。核心教师和员工不仅要掌握技术专长，而且还拥有他们的庞大对基本，临床和转化癌症研究的经验和热情有助于推动科学。这从构思阶段开始，核心人员将参与拟议研究的各个方面通过解释和传播结果发现进行的研究和实验。核心人员将与该项目的临床和实验室人员积极合作，以确保研究和实验设置并最佳地执行。科学发现和严格的范围也不应该是由于缺乏适当和足够的统计方法或计算工具而受到限制也没有受到损害。如果需要和适当，核心人员将扩展现有方法或开发新颖的统计方法或计算工具使该项目的调查人员能够严格解决科学问题和效率。核心还将在统计方法和概念领域提供持续的教育向项目调查人员。