Development of a Novel Virtual Reality Treatment for Emerging Adults with ADHD

开发一种针对患有多动症的新兴成人的新型虚拟现实治疗方法

• 批准号: 10721084
• 负责人: Joshua Morris Langberg
• 金额: $ 59.92万
• 依托单位: RUTGERS, THE STATE UNIV OF N.J.
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-01 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10721084
• 关键词: Address; Adherence; Adult; Algorithms; Attention; Attention deficit hyperactivity disorder; Behavior; Behavior Therapy; Behavioral; Behavioral Mechanisms; Clinical Psychology; Computer software; Data; Development; Disease; Dose; Engineering; Engineering Psychology; Environment; Evaluation; Executive Dysfunction; Eye; Feedback; Focus Groups; Goals; Impairment; Individual; Interruption; Intervention; Libraries; Light; Measures; Mediation; Mediator; Mental Health; Monitor; Motivation; Mus; Parents; Participant; Performance; Pharmaceutical Preparations; Phase; Practice Guidelines; Productivity; Protocols documentation; Psychological reinforcement; Randomized; Randomized, Controlled Trials; Reading; Recommendation; Research Personnel; Resolution; Resources; Rewards; Structure; Students; Surveys; Symptoms; Techniques; Technology; Testing; Time; Traction; Treatment Efficacy; Universities; Visual; Work; Writing; cognitive training; college; computer science; contingency management; distraction; efficacy evaluation; emerging adult; evidence base; experience; follow-up; gaze; health equity; improved; invention; laptop; novel; pilot test; professional atmosphere; randomized trial; support tools; teacher; tool; university student; usability; virtual reality; virtual reality environment; virtual reality headset; virtual reality intervention; virtual world; ward

Project Summary/Abstract Attention deficit hyperactivity disorder (ADHD) is a highly prevalent and impairing disorder. Behavioral treatments that structure the environment and provide frequent and consistent monitoring are efficacious but resource and time intensive, leading to problems with access and adherence. This study will utilize a virtual reality platform to minimize distractions and provide the structure and monitoring necessary for individuals with ADHD to maintain focus while completing homework and studying. The virtual reality (VR) headset will place students in a distraction free environment that automates the frequent and consistent point-of-performance feedback and reinforcement that serves as the core mechanisms of behavioral treatment. The VR technology will allow for direct comparison between two novel intervention approaches and a VR passthrough to laptop control. Survey and objective data (keyboard and mouse click data) will be collected to directly evaluate the impact of VR on core targets of action, including concentration, motivation, and homework effort. This novel alternative to medication and behavior therapy offers a completely new tool for supporting individuals with ADHD. This study includes four separate projects, three in the R61 phase and a large randomized trial in the R33 phase. Project 1 (N = 30 college students with ADHD) focuses on optimizing and refining objective data capture algorithms to quantify on-task behavior and work productivity while completing a variety of different types of academic tasks. Project 2 (N = 30 college students with ADHD) focuses on developing and refining on-task monitoring and performance feedback algorithms within VR, including a green, yellow, and red-light display that allows individuals with ADHD to receive consistent and frequent feedback and work towards specific short-terms goals and rewards. Focus groups will also be completed to improve VR feasibility and usability. Project 3 involves a small randomized controlled trial to ensure that the key targets of action are engaged. Project 3 will assess the feasibility/usability and preliminary effects of the VR environment alone (n=15) as compared to VR environment + contingency management (n=15) and a passthrough control wearing of the VR headset (n=15). Time on-task, homework motivation, and homework effort are the proposed mechanisms of action. If the Go/No-Go criteria are met in Project 3, the protocol moves to Project 4, which involves a randomized trial of the VR intervention. 252 college students with ADHD will be randomized to receive either: (1) VR environment alone, (2) VR environment + contingency management, or (3) pass-through VR headset control for 8 weeks. Measures of mental health and academic functioning will be collected at baseline, 4 weeks, 8 weeks, and at a 3-month follow-up.

项目概要/摘要 注意力缺陷多动障碍（ADHD）是一种非常普遍且损害性的疾病。行为方面 构建环境并提供频繁和一致监测的治疗方法是有效的，但 资源和时间密集，导致访问和依从性问题。本研究将利用虚拟 现实平台，最大限度地减少干扰，并为患有此症的个人提供必要的结构和监控 多动症（ADHD）在完成作业和学习时保持注意力集中。虚拟现实 (VR) 耳机将放置在 学生在一个无干扰的环境中，自动执行频繁且一致的表现点 反馈和强化是行为治疗的核心机制。 VR技术 将允许直接比较两种新颖的干预方法和笔记本电脑的 VR 传输 控制。将收集调查和客观数据（键盘和鼠标点击数据）以直接评估 VR 对行动核心目标的影响，包括注意力、动机和家庭作业努力。这部小说 药物和行为疗法的替代方案为支持患有以下疾病的个人提供了一种全新的工具 多动症。这项研究包括四个独立的项目，其中三个处于 R61 阶段，以及一项大型随机试验 R33相。项目 1（N = 30 名患有多动症的大学生）侧重于优化和提炼客观数据 捕获算法来量化任务行为和工作效率，同时完成各种不同的任务 学术任务的类型。项目 2（N = 30 名患有 ADHD 的大学生）侧重于开发和完善 VR 中的任务监控和性能反馈算法，包括绿灯、黄灯和红灯 显示器让多动症患者能够收到一致且频繁的反馈，并努力实现 具体的短期目标和奖励。焦点小组也将完成，以提高 VR 的可行性和 可用性。项目 3 涉及一项小型随机对照试验，以确保行动的关键目标是 已订婚的。项目3将单独评估VR环境的可行性/可用性和初步效果 (n=15) 与 VR 环境 + 应急管理 (n=15) 和直通控制佩戴相比 VR 耳机的数量 (n=15)。建议完成任务的时间、家庭作业动机和家庭作业努力程度 行动机制。如果项目 3 满足 Go/No-Go 标准，则协议将移至项目 4，其中 涉及 VR 干预的随机试验。 252 名患有多动症的大学生将被随机分配到 接收：(1) 仅 VR 环境，(2) VR 环境 + 应急管理，或 (3) 直通 VR耳机控制8周。心理健康和学业功能的测量将在 基线、4 周、8 周和 3 个月随访时。