Development of a Novel Virtual Reality Treatment for Emerging Adults with ADHD

开发一种针对患有多动症的新兴成人的新型虚拟现实治疗方法

• 批准号: 10721084
• 负责人: Joshua Morris Langberg
• 金额: $ 59.92万
• 依托单位: RUTGERS, THE STATE UNIV OF N.J.
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-01 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10721084
• 关键词: Address; Adherence; Adult; Algorithms; Attention; Attention deficit hyperactivity disorder; Behavior; Behavior Therapy; Behavioral; Behavioral Mechanisms; Clinical Psychology; Computer software; Data; Development; Disease; Dose; Engineering; Engineering Psychology; Environment; Evaluation; Executive Dysfunction; Eye; Feedback; Focus Groups; Goals; Impairment; Individual; Interruption; Intervention; Libraries; Light; Measures; Mediation; Mediator; Mental Health; Monitor; Motivation; Mus; Parents; Participant; Performance; Pharmaceutical Preparations; Phase; Practice Guidelines; Productivity; Protocols documentation; Psychological reinforcement; Randomized; Randomized, Controlled Trials; Reading; Recommendation; Research Personnel; Resolution; Resources; Rewards; Structure; Students; Surveys; Symptoms; Techniques; Technology; Testing; Time; Traction; Treatment Efficacy; Universities; Visual; Work; Writing; cognitive training; college; computer science; contingency management; distraction; efficacy evaluation; emerging adult; evidence base; experience; follow-up; gaze; health equity; improved; invention; laptop; novel; pilot test; professional atmosphere; randomized trial; support tools; teacher; tool; university student; usability; virtual reality; virtual reality environment; virtual reality headset; virtual reality intervention; virtual world; ward

Project Summary/Abstract Attention deficit hyperactivity disorder (ADHD) is a highly prevalent and impairing disorder. Behavioral treatments that structure the environment and provide frequent and consistent monitoring are efficacious but resource and time intensive, leading to problems with access and adherence. This study will utilize a virtual reality platform to minimize distractions and provide the structure and monitoring necessary for individuals with ADHD to maintain focus while completing homework and studying. The virtual reality (VR) headset will place students in a distraction free environment that automates the frequent and consistent point-of-performance feedback and reinforcement that serves as the core mechanisms of behavioral treatment. The VR technology will allow for direct comparison between two novel intervention approaches and a VR passthrough to laptop control. Survey and objective data (keyboard and mouse click data) will be collected to directly evaluate the impact of VR on core targets of action, including concentration, motivation, and homework effort. This novel alternative to medication and behavior therapy offers a completely new tool for supporting individuals with ADHD. This study includes four separate projects, three in the R61 phase and a large randomized trial in the R33 phase. Project 1 (N = 30 college students with ADHD) focuses on optimizing and refining objective data capture algorithms to quantify on-task behavior and work productivity while completing a variety of different types of academic tasks. Project 2 (N = 30 college students with ADHD) focuses on developing and refining on-task monitoring and performance feedback algorithms within VR, including a green, yellow, and red-light display that allows individuals with ADHD to receive consistent and frequent feedback and work towards specific short-terms goals and rewards. Focus groups will also be completed to improve VR feasibility and usability. Project 3 involves a small randomized controlled trial to ensure that the key targets of action are engaged. Project 3 will assess the feasibility/usability and preliminary effects of the VR environment alone (n=15) as compared to VR environment + contingency management (n=15) and a passthrough control wearing of the VR headset (n=15). Time on-task, homework motivation, and homework effort are the proposed mechanisms of action. If the Go/No-Go criteria are met in Project 3, the protocol moves to Project 4, which involves a randomized trial of the VR intervention. 252 college students with ADHD will be randomized to receive either: (1) VR environment alone, (2) VR environment + contingency management, or (3) pass-through VR headset control for 8 weeks. Measures of mental health and academic functioning will be collected at baseline, 4 weeks, 8 weeks, and at a 3-month follow-up.

项目摘要/摘要 注意缺陷多动症（ADHD）是一种高度普遍且受损的障碍。行为 结构环境并提供频繁且一致监测的治疗是有效的，但 资源和时间密集型，导致访问和依从性问题。这项研究将利用虚拟 现实平台以最大程度地减少分心，并为患有的个人提供必要的结构和监控 ADHD在完成作业和学习时保持专注。虚拟现实（VR）耳机将放置 在分心的自由环境中，学生可以自动化频繁且一致的绩效点 作为行为治疗的核心机制的反馈和增强。 VR技术 将可以直接比较两种新颖的干预方法与笔记本电脑的VR通行证 控制。将收集调查和客观数据（键盘和鼠标点击数据），以直接评估 VR对核心行动目标的影响，包括集中精力，动机和家庭作业。这本小说 替代药物和行为疗法为支持个人提供了一种全新的工具 多动症。这项研究包括四个独立的项目，三个在R61阶段，以及一项大型随机试验 R33阶段。项目1（n = 30个ADHD的大学生）专注于优化和完善客观数据 捕获算法以量化任务行为和工作效率，同时完成各种不同的不同 学术任务的类型。项目2（n = 30个ADHD的大学生）专注于开发和完善 VR内的任务监视和性能反馈算法，包括绿色，黄色和红灯 显示允许ADHD的个人可以接收一致且频繁的反馈并致力于 特定的短期目标和奖励。焦点小组也将完成以提高VR的可行性和 可用性。项目3涉及一项小型随机对照试验，以确保行动的关键目标是 已订婚的。项目3将仅评估VR环境的可行性/可用性和初步影响 （n = 15）与VR环境 +应急管理（n = 15）和穿孔控制佩戴相比（n = 15） VR耳机的（n = 15）。拟议的时间是按任务，家庭作业的动力和作业工作 作用机理。如果在项目3中满足了GO/No-Go标准，则该协议将移至项目4，该项目将 涉及VR干预的随机试验。 252个多动症的大学生将被随机分配给 要么接收：（1）单独的VR环境，（2）VR环境 +应急管理或（3）通过 VR耳机控制8周。心理健康和学术功能的度量将在 基线，4周8周，并进行3个月的随访。