Chicago CCFC for the new AsA-NHPI cohort

芝加哥 CCFC 新 AsA-NHPI 队列

• 批准号: 10724064
• 负责人: Briseis A Aschebrook-Kilfoy
• 金额: $ 59.57万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-15 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10724064
• 关键词: Address; Adopted; Adult; Advocacy; Agreement; All of Us Research Program; Ancillary Study; Area; Asian; Asian Americans; Asian population; Behavioral; Cambodian; Censuses; Chicago; Clinic; Clinical; Clinical Protocols; Cohort Studies; Collaborations; Communities; Complement; Consent; Data; Data Collection; Development; Disease; Disparity; Documentation; Enrollment; Ensure; Epidemiology; Equilibrium; Filipino; Focus Groups; Funding; Funding Opportunities; Genetic; Genetic Research; Geography; Goals; Grant; Health; Health Promotion; Home; Human Resources; Institution; Intervention; Investigation; Knowledge; Koreans; Lead; Leadership; Logistics; Medical; Methods; Minority Health Research; Modeling; Molecular; Neighborhoods; Organizational Objectives; Participant; Performance; Phase; Pilot Projects; Precision Health; Prevention; Process; Protocols documentation; Questionnaires; Randomized; Readiness; Research; Research Infrastructure; Research Methodology; Research Personnel; Resources; Sampling; Science; Site; South Asian; Subgroup; Surveys; Training; Underrepresented Minority; United States National Institutes of Health; Universities; Vietnamese; Work; bilingualism; biobank; cohort; collaborative approach; community based participatory research; community engagement; community partnership; community setting; cost; cultural competence; design; diverse data; ethnic diversity; experience; follow-up; health disparity; health equity; improved; innovation; metropolitan; multidisciplinary; outreach; pilot test; population based; population health; racial diversity; recruit; research study; response; social; southeast Asian; success

PROJECT SUMMARY/ABSTRACT The University of Chicago (UChicago) Center for Asian Health Equity (CAHE) and the Institute for Population and Precision Health (IPPH) put forth this plan to leverage decades of experience enrolling underrepresented minorities, and especially Asian Americans, into health studies and epidemiologic cohorts as a clinic/community field site for the new NIH-funded AsA-NHPI Cohort (NAC). We plan to enroll 2,500 participants from communities in the metropolitan Chicago area with large Asian subgroup representation using a population-based sampling framework. We will specifically target South Asian, Korean, Filipino and Southeast Asians (Cambodian, Vietnamese, and Laotian) in randomized census tracts using a 2-stage sampling design. Our long-term partner, the Asian Health Coalition (AHC) has been serving as the national engagement lead for the All of Us Research Program and has set the national model for community engaged cohorts tailored to Asian inclusion. We have identified active community partners who are already supporting enrollment into a similar protocol. In this proposal, the UChicago MPIs and team enthusiastically propose a collaborative approach to meet the RFA milestones; building on prior success and experience working on national multisite cohorts with an emphasis on racial diversity, scientific rigor, and innovative approaches to improve health disparities. We suggest an approach and methods for consideration for the common protocol during the UG3 period, with full appreciation for the balance of decisions that will need to be made to ensure efficient recruitment, comprehensive yet not burdensome surveys, thoughtful clinical protocols that can be implemented in a community or in-home setting, and high-quality biospecimens processed and banked to support scientific investigation and ancillary studies. We plan to hire bilingual, bicultural individuals from the Asian community and train them to work as “community ambassadors (CAs)” during the entire study period, a model that has proven highly effective in Asian communities previously, promoting both participation and retention. We have an institutional commitment to deploy mobile medical units (MMUs) and study vans to targeted study areas at no cost to the grant to ensure that we can lower barriers to participation. We are confident that our proposed approach will allow us to meet the cohort UG3 and UH3 milestones, short-, mid- and long-term goals, and contribute significantly to this important effort in all phases.

项目概要/摘要 芝加哥大学 (UChicago) 亚洲健康公平中心 (CAHE) 和人口研究所 和 Precision Health (IPPH) 提出这一计划是为了利用数十年招收代表性不足的经验 少数族裔，尤其是亚裔美国人，将其纳入健康研究和流行病学队列作为 NIH 资助的新 AsA-NHPI 队列 (NAC) 的诊所/社区现场网站 我们计划招募 2,500 人。 来自芝加哥大都市地区社区的参与者，其中有大量亚洲亚群体代表 我们将特别针对南亚裔、韩国裔、菲律宾裔和菲律宾裔。 使用两阶段随机人口普查区域中的东南亚人（柬埔寨人、越南人和老挝人） 我们的长期合作伙伴亚洲健康联盟（AHC）一直担任国家抽样设计。 “我们所有人研究计划”的参与领导者，并为社区参与树立了国家模式 我们已经确定了针对亚洲包容性的积极社区合作伙伴。 在这项提案中，芝加哥大学 MPI 和团队热情地提出了一项类似的协议。 以先前的成功和经验为基础，以协作方式实现 RFA 里程碑； 全国多地点队列，重点关注种族多样性、科学严谨性和创新方法 我们建议考虑共同方案的方法和方法。 在 UG3 期间，充分认识到需要做出的平衡决定，以确保 高效的招募、全面但不繁重的调查、深思熟虑的临床方案 在社区或家庭环境中实施，并处理和存储高质量的生物样本 支持科学研究和辅助研究。 亚裔社区并培训他们在整个学习期间担任“社区大使（CA）”， 这种模式之前已在亚洲社区被证明非常有效，既促进了参与，又促进了 我们有机构承诺部署移动医疗单位 (MMU) 和学习车 免费资助有针对性的研究领域，以确保我们能够降低参与障碍。 相信我们提出的方法将使我们能够实现 UG3 和 UH3 队列的里程碑，短期、中期 和长期目标，并在各个阶段为这一重要努力做出重大贡献。