Southeast Collaborative for Innovative and Equitable Solutions to Chronic Disease Disparities

东南合作以创新和公平的方式解决慢性病差异

基本信息

批准号：
10657748
负责人：
Nancy J Cox
金额：
$ 248.3万
依托单位：
VANDERBILT UNIVERSITY MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-09-24 至 2026-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10657748
关键词：
Academic Medical Centers Address African American African American population Asthma Award Behavior Behavioral Bioinformatics Biological Black Populations Black race Cardiovascular Diseases Cause of Death Cessation of life Chronic Chronic Disease Clinical Collaborations Communities Community Health Aides Complex Data Data Science Decision Making Dentists Diabetes Mellitus Disadvantaged minority Discipline Discrimination Disparity Doctor of Philosophy Environment Equity Faculty Fostering Genetic Glycosylated hemoglobin A Health Health Disparities Research Health Expenditures Health Insurance Health Professional Health Services Accessibility Health system Hispanic Home Human Hypertension Individual Infrastructure Institution International Intervention Latino Latino Population Lead Link Malignant Neoplasms Medicine Mentors Minority Obesity Operative Surgical Procedures Outcome Patients Personal Satisfaction Physicians Policies Population Poverty Prevention Psyche structure Quality of life Research Research Personnel Resources Risk Risk Factors Risk Reduction Rural Community Science Scientist Secure Services Sleep Social Work Social support Socioeconomic Status Southeastern United States Stephania Structural Racism Structure Technology Testing Time Tobacco use Training Trauma United States Public Health Service Universities Urban Community Vascular Diseases adaptive intervention career development community engagement community intervention coping mechanism data harmonization design diabetes management disease disparity ethnic health disparity ethnic minority experience family support genomic data health data health disparity health equity health inequalities implementation science improved innovation mHealth medical schools novel personalized medicine phenotypic data population health premature prevent preventable death professional atmosphere professor programs racial health disparity racial minority racism skills social social health determinants

项目摘要

The burden of racial and ethnic health disparities is most evident in the southeastern United States, where Black and Latino populations suffer the highest rates of cardiovascular disease, diabetes, obesity, hypertension, cancer, and asthma. These chronic conditions are a primary cause of poor health, reduced quality of life, and premature death, and account for more than 50% of health care expenditures. Despite substantial reduction of some chronic diseases and risk factors over the last few decades, the Southeast continues to have the highest number of potentially preventable deaths for each of the five leading causes of death. Racial and ethnic minorities comprise 39% of the population of the Southeast (HHS Region IV), which includes nearly 15 million African Americans and 9 million Latinos. Minorities in the Southeast fare worse on many health indicators compared to other regions, in large part due to poor socioeconomic status, with more than 22% of Southeastern residents living in poverty. Effectively addressing pervasive chronic disease disparities will require interventions that consider the needs, priorities, and lived experiences of those disproportionately impacted. Research teams with expertise in social, environmental, behavioral, and biological disciplines must collaborate to develop and test multicomponent strategies aimed at the multilevel determinants that drive disparities. Via a new center - the Southeast Collaborative for Innovative and Equitable Solutions to Chronic Disease Disparities, we will bring together Vanderbilt University Medical Center, University of Miami, and Meharry Medical College to address to reduce risk factors for and disparities in diabetes, cardiovascular disease, obesity, and related conditions among African American and Latino populations in the Southeast. We aim to: Specific Aim 1: Establish the human and technical infrastructure to foster highly collaborative, transdisciplinary research collaborations focused on using technology and data science to reduce chronic disease disparities among African American and Latino populations in the southeastern United States. Specific Aim 2: Facilitate a regional, cross-institutional pilot awards program focused on chronic disease disparities that nurtures and supports career development, advances use of data science, technology, and bioinformatics to address the complex drivers of health disparities, and promotes inclusive excellence. Specific Aim 3: Propel novel health disparities research leveraging technology, individual-level and community- level social determinants of health data, and genomic and phenotypic data to prevent, treat, and manage diabetes, cardiovascular disease, obesity and related conditions in African American and Latino populations. Specific Aim 4: Partner with African American and Latino communities in the Southeast integrate their priorities into the Center’s infrastructure, and collaboratively develop, adapt, and test socially and culturally appropriate interventions to secure the earliest impact on eliminating chronic disease disparities.

在美国东南部黑人和拉丁裔种群的心血管疾病，糖尿病，肥胖，高血压，癌症和哮喘。这些慢性病是健康不良，生活质量降低的主要原因，以及过早死亡，占医疗保健支出的50％以上。尽管大幅减少在过去的几十年中，一些慢性疾病和危险因素，东南部仍然具有最高五个主要的死亡原因中的每一个可能可预防的死亡人数。种族和少数民族占东南部人口（HHS IV）的39％，其中包括将近1500万非裔美国人和900万拉丁美洲人。东南部的少数民族在许多健康方面都差得多与其他地区相比，指标很大程度上是由于社会经济地位差，其中22％以上居住在贫困中的东南居民。有效解决普遍存在的慢性疾病分布将需要考虑到不成比例影响的需求，优先事项和生活经验的干预措施。在社会，环境，行为和生物学学科方面具有专业知识的研究团队必须协作开发和测试针对驱动分布的多级决定者的多组分策略。通过一个新中心 - 东南部的创新和公平解决方案的合作疾病差异，我们将汇集范德比尔特大学医学中心，迈阿密大学和 Meharry医学院要解决糖尿病，心血管疾病的危险因素和差异的问题，东南非裔美国人和拉丁裔人口的肥胖和相关条件。我们的目标是：特定目的1：建立人类和技术基础设施以促进高度协作，跨学科研究合作的重点是使用技术和数据科学减少慢性病分布在美国东南部的非裔美国人和拉丁裔人口中。特定目的2：促进针对慢性病的区域跨机构试点奖计划护士和支持职业发展的差异，数据科学的使用，技术，技术和生物信息学以应对健康分布的复杂驱动因素，并促进卓越的卓越。特定目的3：推动新型健康差异研究利用技术，个人级别和社区 - 将健康数据的社会决定者以及基因组和表型数据进行预防，治疗和管理非裔美国人和拉丁裔人群中的糖尿病，心血管疾病，肥胖和相关状况。特定目标4：与东南部的非裔美国人和拉丁裔社区合作将其优先事项融为一体进入中心的基础架构，并在社会和文化上进行协作，适应和测试干预措施以确保消除慢性疾病分布的最早影响。