Core A: Administrative Core

核心A：行政核心

• 批准号: 10653098
• 负责人: Justin D. Lathia
• 金额: $ 13.1万
• 依托单位: CLEVELAND CLINIC LERNER COM-CWRU
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-14 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10653098
• 关键词: Accounting; Animal Experimentation; Animals; Awareness; Bioinformatics; Biometry; Cancer Biology; Collaborations; Communication; Core Facility; Data; Data Set; Development Plans; Documentation; Drug Screening; Ensure; Epigenetic Process; Experimental Models; Feedback; Funding; Glioma; Goals; Grant; Human; Human Resources; Human Subject Research; Individual; Institution; Iron; Leadership; Manuscripts; Microglia; Modeling; Monitor; National Cancer Advisory Board; National Cancer Institute; Office of Administrative Management; Oral; Performance; Postdoctoral Fellow; Preparation; Program Research Project Grants; Progress Reports; Research; Research Personnel; Resources; Schedule; Scientist; Services; Sex Differences; Study Subject; System; Time; Training; Work; Writing; drug metabolism; experience; human subject; innovation; meetings; operation; programs; recruit; sex; stem; tumor microenvironment

PROJECT SUMMARY The Administrative Core is responsible for the overall leadership and management of the Program Project Grant (P01), and it will provide overall organizational, administrative, and scientific management. The Administrative Core will oversee and coordinate all P01 components and centrally monitor and evaluate their performance. In addition, the Administrative Core will facilitate all interactions with the Internal Advisory Board (IAB) and External Advisory Board (EAB). This P01 application involves 6 institutions and 5 key investigators, as Project and Core leaders. The Administrative Core will be essential in coordinating all communications and reviewing all activities among Projects and Cores that will take place across the participating institutions. The Administrative Core will administer all the subcontracts, work closely with all participating institutions in order to use existing facilities and build upon those when required, and ensure that best practices for animal studies and human subjects research are met and monitored appropriately. It will additionally ensure that access to all scientific core facility services are managed to ensure that the overall goals of the P01 are met. The Administrative Core personnel will be led by Dr. Lathia, with collaboration from Drs. Barnholtz-Sloan and Waite and Ms. Schiciano. Both Drs. Lathia and Barnholtz-Sloan have extensive experience in managing multi-institution programs. The proposed P01 team has a successful record of accomplishment of working together on multiple collaborative efforts. The Specific Aims are:1) To provide all organizational, administrative, and scientific leadership for the P01 Projects and Cores by cultivating and promoting the P01 team through innovation and excellence, leveraging resources, and providing constructive feedback; 2) To provide administrative management for all fiscal management of the P01 including but not limited to accounting of grant funds, progress reports, communication, meeting scheduling and minutes, and manuscript and grant preparation; 3) To evaluate research progress through oral and written documentation, with regular input from the IAB, EAB, and National Cancer Institute (NCI) leadership in order to ensure that each project is meeting its objectives within the proposed time frame; 4) To ensure and monitor best practices for human subjects and animal research for all P01 Projects and Cores; data operations (in collaboration with the Biostatistics and Bioinformatics Core); and adequate human and animal biospecimens for all projects (in collaboration with the Experimental Models Core); and 5) To raise awareness of the P01 through promotion of seminars, recruitment of postdoctoral fellows, scientific exchanges, coordination of an annual scientific retreat involving the scientists in the P01, and through training and development plans that will ensure state-of-the-art practices.

项目摘要 行政核心负责计划项目赠款的整体领导和管理 （P01），它将提供整体的组织，行政和科学管理。行政 核心将监督和协调所有P01组件，并集中监视和评估其性能。在 此外，行政核心将促进与内部咨询委员会（IAB）和外部的所有互动 顾问委员会（EAB）。该P01申请涉及6个机构和5位主要调查人员，作为项目和核心 领导者。行政核心对于协调所有沟通和审查所有活动至关重要 在参与机构将发生的项目和核心中。行政核心将 管理所有分包合同，与所有参与机构紧密合作，以便使用现有设施和 在需要的情况下以这些为基础，并确保动物研究和人类受试者的最佳实践研究 适当地满足和监视。它将确保访问所有科学核心设施服务 设法确保满足P01的整体目标。行政核心人员将被领导 Lathia博士与博士合作。 Barnholtz-Sloan和Waite和Schiciano女士。两个博士。 lathia和 Barnholtz-Sloan在管理多机构计划方面拥有丰富的经验。拟议的P01团队有 成功完成多次协作努力的成功记录。具体目标 是：1）为P01项目和核心提供所有组织，行政和科学领导 通过创新和卓越，利用资源并提供的P01团队培养和促进P01团队 建设性的反馈； 2）为P01的所有财政管理提供行政管理，包括 但不仅限于赠款资金，进度报告，沟通，会议时间表和会议记录， 和手稿和赠款准备； 3）通过口头和书面文档评估研究进展， IAB，EAB和国家癌症研究所（NCI）领导的定期投入，以确保每个 项目在拟议的时间范围内实现其目标； 4）确保并监视最佳实践 所有P01项目和核心的人类受试者和动物研究；数据操作（与 生物统计学和生物信息学核心）；以及所有项目的足够人类和动物生物测量（在 与实验模型核心的合作）； 5）通过促进提高对P01的认识 研讨会，博士后研究员的招募，科学交流，年度科学务虚会的协调 通过培训和发展计划，使科学家参与P01，以确保最先进 实践。