Biostatistics Core

生物统计学核心

• 批准号: 10631868
• 负责人: Peihua Qiu
• 金额: $ 10.12万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-06-01 至 2027-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10631868
• 关键词: Adherence; Aging; American; Attention; BCL1 Oncogene; Biological Aging; Biometry; Biostatistical Methods; Biostatistics Core; Cancer Center; Capsicum; Clinical Data; Clinical Research; Clinical Trials Design; Collaborations; Computer software; Computers; Data; Data Analyses; Data Collection; Data Management Resources; Data Science; Data Security; Databases; Development; Discipline; Disease; Early Diagnosis; Elderly; Ensure; Extramural Activities; Faculty; Florida; Funding; Future; Genetic; Geroscience; Goals; Health; Human Resources; Leadership; Manuscripts; Measurement; Measures; Metabolism; Methodology; Methods; Mission; Monitor; Outcome; Pattern; Periodicals; Phase; Physical Performance; Preparation; Procedures; Protocols documentation; Publications; Qualifying; Quality Control; Randomized; Research; Research Design; Research Personnel; Resources; Sample Size; Scheme; Scientist; Services; Site; Source; Statistical Computing; Statistical Data Interpretation; Statistical Methods; Technology; Testing; Time; Training; Translational Research; Universities; Writing; biomarker discovery; computerized data processing; data collection site; data management; data repository; design; education research; experience; genomic data; image processing; interdisciplinary approach; interest; intervention effect; power analysis; preclinical study; programs; recruit; research and development; research data dissemination; screening; tool; web app

Abstract The Biostatistics Core (RC3) is one of the four resource cores in the Claude D. Pepper Older Americans Independence Center (OAIC) at the University of Florida (UF). The mission of the UF OAIC is twofold: 1) to enhance late-life mobility and independence through interdisciplinary approaches to optimize physical performance and mobility, and 2) to train new investigators in research on aging, mobility, and independence, while developing their leadership abilities. The RC3 is a key cog in the interaction among scientists from diverse disciplines to accomplish this mission. It provides research-design and statistical-analysis resources, and helps construct data-collection forms and manage the data (including providing quality control) for both preclinical and clinical studies conducted within the OAIC. The RC3 is involved in all phases of the OAIC studies, and it helps with initial pre-proposal study design and sample-size calculations, development of randomization plans for data collection, and state-of-the-art statistical analyses once the data are collected. It also helps with manuscript preparation for research dissemination. In addition, the RC3 serves as a key resource to OAIC new faculty and Research Education Core (REC) Scholars, by providing them consulting services and periodic special-interest trainings in topics, such as study design, power analysis, data management, study implementation and management, and basic statistical methods and tools. Finally, for OAIC studies where the existing biostatistical methodologies are inadequate, the RC3 has assembled strong expertise for developing new biostatistical methods and tools that are beyond the current practice.

抽象的 生物统计学核心（RC3）是Claude D. Pepper D.美国人的四个资源核心之一 佛罗里达大学（UF）的独立中心（OAIC）。 UF OAIC的任务是双重的：1） 通过跨学科的方法来增强晚期流动性和独立性，以优化物理 绩效和流动性，以及2）培训有关衰老，移动性和独立研究的新调查人员的培训， 在发展他们的领导能力的同时。 RC3是科学家之间相互作用的关键齿轮 多样化的学科来完成这一任务。它提供研究设计和统计分析资源， 并有助于构建数据收集表格，并管理数据（包括提供质量控制） 在OAIC内进行的临床前和临床研究。 RC3参与了OAIC研究的所有阶段，它有助于最初的提交前研究设计和 样本大小的计算，数据收集随机计划的制定以及最先进的统计 分析一旦收集数据。它还有助于为研究传播做准备。在 此外，RC3是OAIC新教师和研究教育核心（REC）的关键资源（REC） 学者，通过为他们提供咨询服务和定期特殊利益培训，例如 设计，电源分析，数据管理，研究实施和管理以及基本统计 方法和工具。最后，对于现有生物统计学方法不足的OAIC研究， RC3汇集了强大的专业知识，用于开发超出超越的新生物统计学方法和工具 当前的做法。