UCSF Environmental Research and Translation for Health Center (EaRTH Center)

加州大学旧金山分校健康中心环境研究与翻译（EaRTH 中心）

• 批准号: 10382448
• 负责人: Tracey J. Woodruff
• 金额: $ 131.63万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-05-22 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10382448
• 关键词: Address; Affect; Analytical Chemistry; Animal Model; Bioinformatics; Biological; Biological Assay; Biomedical Research; California; Cell Nucleus; Cell model; Chemical Exposure; Chemicals; Child; Chronic Disease; Clinical; Clinical Medicine; Clinical Research; Clinical Sciences; Collaborations; Communication; Communities; Community Outreach; Complex; Consultations; Core Facility; Data; Dentistry; Development; Diabetes Mellitus; Discipline; Disease; Educational Curriculum; Environment; Environmental Exposure; Environmental Health; Environmental Risk Factor; Epidemiology; Exposure to; Family; Funding; Future; Goals; Health; Health Professional; Health Sciences; Healthcare; Human; Infrastructure; Institution; International; Intervention; Investigation; Laboratories; Leadership; Link; Location; Longevity; Malignant Neoplasms; Measurement; Measures; Mediating; Medical; Medical Students; Medicine; Mentors; Mentorship; Modeling; National Institute of Environmental Health Sciences; Neurodevelopmental Disorder; Obesity; Pathway interactions; Patients; Peer Review; Pharmacy facility; Pilot Projects; Planet Earth; Positioning Attribute; Prevalence; Prevention; Prevention education; Production; Proteomics; Publishing; Reproduction; Reproductive Health; Research; Research Design; Research Personnel; Resources; Role; San Francisco; School Nursing; Schools; Science; Scientist; Students; Technology; Training; Translating; Translational Research; Translations; Underserved Population; Universities; Vulnerable Populations; Women' s Health; Work; career; community engagement; data integration; education resources; environmental chemical; environmental stressor; health data; health literacy; healthcare community; high throughput screening; human tissue; improved; in vivo; insight; interdisciplinary collaboration; member; men; next generation; operation; outreach; prevent; programs; ranpirnase; reproductive; social stressor; tool

The overall goal of the new University of California, San Francisco (UCSF) Environmental Research and Translation for Health (EaRTH) Center is to accelerate the pace of recognizing and preventing environmental exposures that affect reproduction and development to improve human health across the lifespan. Addressing the complex problems of environmental health requires partnerships across disciplines; mobilization of technology for identification, intervention, and prevention; and education of future scientists and clinicians and the public. The EaRTH Center is uniquely positioned to address these challenges and advance environmental health. By virtue of its location at UCSF—a premier institution for biomedical research, translation of research findings, and clinical training—and its strong interdisciplinary team, the EaRTH Center will fill a critical gap in a prominent clinical and biomedical research setting. Our proposed UCSF P30 EaRTH Center will allow us to: create opportunities for new research directions in environmental health at UCSF that are not currently possible; nurture and sustain transdisciplinary research collaborations across a network of academics and diverse UCSF departments to advance our understanding of the relationship between environment and disease; mentor and grow the next generation of research and clinical leaders in environmental health; and embed environmental health literacy within health care to accelerate prevention of environmentally mediated diseases. Our Center tightly integrates 4 cores and 1 program: 1) an Administrative Core to provide leadership, infrastructure, administrative and communication support, advice and oversight to coordinate all EaRTH Center operations; 2) an Integrated Health Sciences Facility Core (IHSFC) that will provide consultation on study design, data integration, data of environmental and social stressors, and translation and dissemination of research findings; 3) a Bioassay Facility Core that will provide state-of-the-art tools for measuring chemical exposures and their effects on biological pathways; 4) a Community Engagement Core (CEC) to expand environmental health education and resources for students and health professionals to embed environmental health within health care; and 5) a Pilot Project Program to fund transdisciplinary projects enabling researchers to enter the field or add an environmental component to their current research. Our integrated Center will lead to new scientific understandings in environmental health tightly linked to our community outreach work, which will shift the fundamental understanding of the role of environment in disease, leading to solutions to preventing harmful exposures and improving health.

加利福尼亚大学新大学旧金山（UCSF）环境研究的总体目标 健康中心的翻译（地球）中心是加快认可和防止的速度 环境暴露会影响繁殖和发展以改善整个生命周期的人类健康。 解决环境健康的复杂问题需要跨学科的伙伴关系；动员 用于识别，干预和预防的技术；以及对未来科学家和临床医生的教育以及 公众。地球中心的位置是应对这些挑战和前进的环境的独特位置 健康。凭借其位于UCSF的位置 - 一家主要的生物医学研究机构，研究翻译 调查结果和临床培训 - 地球中心的强大跨学科团队将填补一个关键的空白 重要的临床和生物医学研究环境。我们提出的UCSF P30地球中心将使我们能够： 为UCSF的环境健康新研究方向创造机会，目前是不可能的； 护士和维持跨学者和UCSF潜水的跨学科研究合作 部门促进我们对环境与疾病之间关系的理解；导师和 发展下一代研究和环境健康领域的临床领导者；并嵌入环境 医疗保健中的健康素养，以加速预防环境介导的疾病。我们的中心 紧密整合的4个核心和1个计划：1）提供领导，基础设施的行政核心， 行政和沟通支持，建议和监督，以协调所有地球中心运营； 2） 一个综合健康科学设施核心（IHSFC），将提供有关研究设计的咨询 整合，环境和社会压力源的数据以及研究结果的翻译和传播； 3）生物测定设施核心，该核心将提供用于测量化学暴露及其的最先进工具 对生物途径的影响； 4）社区参与核心（CEC）扩大环境健康 学生和卫生专业人员的教育和资源将环境卫生嵌入卫生保健中； 5）一项试点项目计划，用于资助跨学科项目，使研究人员能够进入该领域或添加 他们当前研究的环境组成部分。我们的综合中心将导致新的科学 环境健康的理解与我们的社区外展工作紧密相关，这将改变 对环境在疾病中的作用的基本了解，导致了防止有害的解决方案 暴露并改善健康。