Prevention Research Center: Parenting Among Women Who Are Opioid Users

预防研究中心：阿片类药物使用者的女性育儿

• 批准号: 10472797
• 负责人: Philip A Fisher
• 金额: $ 77.79万
• 依托单位: UNIVERSITY OF OREGON
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-30 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10472797
• 关键词: 2019-nCoV; Address; Adoption; Affect; American; Area; CLIA certified; COVID-19; COVID-19 diagnostic; COVID-19 disparity; COVID-19 health disparity; COVID-19 pandemic; COVID-19 testing; Centers for Disease Control and Prevention (U.S.); Charge; Child Rearing; Communication; Communities; Community Outreach; County; Data Collection; Data Science; Development; Diagnostic tests; Equipment and Supplies; Evaluation; Event; Family; Feedback; Foundations; Friends; Future; Genomics; Goals; Health; Health Promotion; Health behavior; Hospitals; Individual; Infection; Infrastructure; Intervention; Laboratories; Laboratory Personnel; Latinx; Latinx population; Leadership; Location; Logistics; Methods; Modeling; Molecular; Molecular Biology; Morbidity - disease rate; Motivation; Oregon; Pamphlets; Penetration; Phase; Population; Prevention; Prevention Research; Protocols documentation; Public Health; RADx Underserved Populations; Ramp; Research; Research Personnel; Research Project Grants; Resources; SARS-CoV-2 infection; Science; Scientist; Site; Structure; System; Testing; Time; Underserved Population; United States; Vaccination; Virus; Visit; Woman; Work; base; behavior test; burden of illness; community based participatory research; community engagement; design; efficacious intervention; experience; health disparity; health literacy; implementation science; improved; laboratory experience; laboratory facility; mortality; operation; opioid user; outreach; outreach services; pandemic disease; programs; psychoeducation; randomized trial; recruit; research study; respiratory; response; scale up; social determinants; substance use; testing uptake; tool; transmission process; uptake; vulnerable community

PROJECT SUMMARY The global SARS-CoV-2 pandemic that causes the severe respiratory illness COVID-19 is the worst health crisis the United States has faced in a century. Although this highly contagious virus has infected millions of Americans already, the disease burdens are disproportionately born by historically underserved populations such as Latinx communities. Nationally, Latinx people with COVID-19 are hospitalized at four times the rate of Whites and have much higher rates of morbidity and mortality. This disparity is notable in Oregon, where the 13% of our population that is Latinx represents approximately 44% of COVID-19 cases. An urgent need exists to reach Oregon’s Latinx community with public health and prevention messages to increase testing. This project will implement a culturally-tailored community outreach and testing program to increase the reach, access, and uptake of testing in Latinx communities in Oregon. The project will bring together a world-class team of prevention scientists, public health experts, Latinx researchers, community partners, and biologists who have been working together to conduct SARS-CoV-2 diagnostic testing since March, soon after the pandemic first arrived in the U.S. This team has established a CLIA-certified laboratory and honed molecular testing protocols, hired and trained laboratory personnel and a field research team, procured diagnostic testing equipment and supplies, and partnered with county public health offices and hospitals throughout the state to conduct testing. The team also conducted a comprehensive community assessment using community-based participatory methods to gather Latinx community feedback on modes of communication, health messages, and testing protocols, and staffed multiple county-led testing sites serving Latinx communities. Using these resources and expertise as a foundation, a Sequential Multiple Armed Randomized Trial (SMART) will enable the evaluation of strategies for increasing testing rates and promoting health behaviors in Latinx communities. Specifically, culturally informed, community-oriented interventions will determine tools and best practices to increase testing rates and health behaviors. The efficacy of different types of approaches for increasing access to and utilization of testing will be evaluated. Lastly, the work will examine a set of county-level variables thought to affect communities’ abilities to sustain testing capacity. With support from a Latinx Community and Scientific Advisory Board, the project will ramp up to ultimately support 36 community testing sites across six counties in Oregon to serve Latinx communities. Over time, this project will help communities institutionalize optimal local testing frameworks supported by UO laboratory facilities for testing capacity, technical support for testing logistics, and collection of data on health behaviors, testing rates, and sustainability. The resulting structures and systems will be poised for future scale-up to other vulnerable communities and/or for other public health purposes (e.g., vaccination campaigns). If successful, this project will lead to a major reduction in COVID-19 health disparities in underserved populations.

项目概要 导致严重呼吸道疾病 COVID-19 的全球 SARS-CoV-2 大流行是最糟糕的健康状况 尽管这种传染性极强的病毒已经感染了数百万人，但这是美国一个世纪以来面临的危机。 美国人已经发现，疾病负担不成比例地由历史上服务不足的人群承担 例如，在全国范围内，拉丁裔社区感染 COVID-19 的人数是其他人的四倍。 白人的发病率和死亡率要高得多，这种差异在俄勒冈州尤为明显。 拉丁裔人口占我们人口的 13%，约占 COVID-19 病例的 44%，存在迫切需求。 向俄勒冈州的拉丁裔社区传达公共卫生和预防信息，以增加检测。 项目将实施针对文化的社区外展和测试计划，以扩大覆盖范围， 该项目将汇集俄勒冈州拉丁裔社区的测试机会和接受情况。 由预防科学家、公共卫生专家、拉丁裔研究人员、社区合作伙伴和生物学家组成的团队 自 3 月份以来，即疫情爆发后不久，他们一直在共同努力进行 SARS-CoV-2 诊断检测 大流行首先抵达美国 该团队建立了 CLIA 认证的实验室并磨练了分子 测试方案、雇用和培训实验室人员和现场研究团队、采购诊断测试 设备和用品，并与全州县公共卫生办公室和医院合作， 该团队还使用基于社区的方式进行了全面的社区评估。 收集拉丁裔社区对沟通方式、健康信息、 和测试协议，并配备了多个县领导的测试站点，为拉丁裔社区提供服务。 以资源和专业知识为基础，序贯多组随机试验 (SMART) 将能够 对提高拉丁裔社区检测率和促进健康行为的策略进行评估。 具体而言，以文化为基础、以社区为导向的干预措施将确定工具和最佳实践，以 提高检测率和健康行为的有效性。 最后，该工作将检查一组县级变量。 在拉丁裔社区的支持下，社区的想法会影响维持测试能力的能力。 科学咨询委员会表示，该项目将逐步扩大规模，最终支持 6 个地区的 36 个社区测试站点 随着时间的推移，该项目将帮助俄勒冈州各县实现拉丁裔社区制度化。 由俄勒冈大学实验室设施支持的最佳本地测试框架，以提高测试能力和技术支持 测试物流，以及收集有关健康行为、测试率和可持续性的数据。 结构和系统将准备好将来扩展到其他弱势社区和/或其他 公共卫生目的（例如疫苗接种活动）如果成功，该项目将导致大幅减少。 服务不足人群中的 COVID-19 健康差异。