Prevention Research Center: Parenting Among Women Who Are Opioid Users

预防研究中心：阿片类药物使用者的女性育儿

基本信息

批准号：
10399164
负责人：
Philip A Fisher
金额：
$ 0.58万
依托单位：
UNIVERSITY OF OREGON
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-08-15 至 2024-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10399164
关键词：
Affect Area Awareness Basic Science Behavior Behavioral Brain Child Child Rearing Collaborations Communication Communities Community Networks Community Services County Criminal Justice Data Data Science Core Development Drug Addiction Drug usage Economic Burden Educational workshop Epidemic Evaluation Evidence based intervention Exposure to Family Female Funding General Population Generations Geography Goals Grant Health Healthcare Helping to End Addiction Long-term Individual Infant Development Infrastructure Intervention Investigation Knowledge Leadership Link Manuscripts Measures Methods Modeling Mothers National Institute of Drug Abuse Neurobiology Neurocognitive Opiate Addiction Opioid Oregon Outcome Parent-Child Relations Parents Personal Satisfaction Policies Policy Maker Population Population Intervention Postpartum Period Pregnant Women Prevention Prevention Research Prevention program Productivity Public Health Publications Recording of previous events Regulation Research Research Methodology Research Personnel Research Project Grants Resources Rewards Risk Rural Rural Community Science Scientist Seminal Stress Structure System Testing Training Training Activity Translational Research United States United States Dept. of Health and Human Services United States National Institutes of Health Universities Vulnerable Populations Woman Work addiction age group base career career development checkup examination child bearing community partnership cost data harmonization data sharing design drug use vulnerability early childhood early life adversity economic cost effective intervention effectiveness evaluation epidemiologic data evidence base executive function experience improved individualized prevention innovation intergenerational knowledge base maternal opioid use member multidisciplinary next generation novel opioid abuse opioid epidemic opioid misuse opioid use opioid use disorder opioid user overdose death prescription opioid prescription opioid misuse preventive intervention programs public health emergency recruit rural area service providers skills substance abuse prevention substance use therapy design transmission process webinar

项目摘要

7. PROJECT SUMMARY/ABSTRACT The United States is experiencing an opioid epidemic of historic significance, with over 40,000 deaths from overdose in the past year. The economic costs of the epidemic in 2015 alone were estimated at over $500 billion, and in 2017 the US Department of Health and Human Services designated the opioid epidemic as a public health emergency. National-level epidemiological data indicate that the rates opioid misuse, addiction, overdose, and fatalities are increasing at a particularly fast rate among women, and among individuals in child- bearing and child-rearing age groups. Opioid-using behaviors among women who are parenting can have significant detrimental effects on their parenting, parent-child relationships, and downstream effects on child brain development, health, and subsequent risk for drug use. The lack of a strong scientific knowledge base about effective strategies for reducing opioid abuse and addiction in this population is a gap of enormous consequences given the well-established effects of substance use on parenting skills, and the known effects of maternal opioid use on infant development. The limited research on this topic that does exist suggests that family-focused treatment approaches may hold the greatest promise, but the interventions that have been developed to date have limitations in terms of scalability. In addition to a need for scientific research on this topic, there is a parallel need to make reliable information available to researchers, policy makers, and the general public. The overall goal of the Prevention Research Center: Parenting Among Women Who Are Opioid Users (PWO Center) is to improve the well-being of individuals, families, and communities affected by the opioid crisis through a focus on behavioral (parental responsivity, warmth) and neurocognitive systems (e.g., executive functioning, reward responsiveness) that are underlying mechanisms common to both addiction issues and parenting challenges. The PWO Center's Research Projects and Cores are based upon a unifying conceptual model and employ a translational science approach in which basic science investigations of underlying mechanisms are leveraged in the development and evaluation of scalable interventions that are designed to deliver population-level impacts on policy and practice. Our multidisciplinary investigative team has been conducting research on family-based parenting interventions for families with substance use histories for the past 20 years and has a long and productive history of collaboration and productivity. We have strong support for the proposed PWO Center from our state governor, our community partners, and our university leadership. The anticipated long-term, public health outcomes of the PWO Center are to improve evidence- based prevention of substance abuse, reduce maternal opioid misuse and addiction, reduce intergenerational transmission of drug addiction, increase scientific understanding and public awareness of how opioids impact maternal parenting practices via underlying behavioral and neurocognitive mechanisms, ready the next generation of researchers and practitioners in this area, and increase evidence-based policy.

7。项目摘要/摘要美国正在经历历史意义的阿片类药物流行，死亡超过40,000人过去一年过量。仅2015年流行病的经济成本估计超过500美元十亿美元，2017年美国卫生与公共服务部将阿片类药物的流行指定为一种公共卫生紧急情况。国家一级流行病学数据表明，阿片类药物滥用，成瘾，用药过量，死亡人数在女性中以及儿童中的个体中以特别快的速度增加 - 轴承和育儿年龄段。育儿的女性中使用阿片类药物的行为可以对他们的育儿，亲子关系以及对儿童的下游影响的重大不利影响大脑发育，健康以及随后的吸毒风险。缺乏强大的科学知识基础关于减少该人群中阿片类药物滥用和成瘾的有效策略是巨大的差距鉴于物质使用对育儿技能的公认影响以及已知影响的后果产妇阿片类药物在婴儿发育中使用。关于此主题的有限研究表明以家庭为中心的治疗方法可能会有最大的前景，但是迄今为止开发的在可伸缩性方面有局限性。除了需要科学研究主题，需要提供可靠的信息，以便为研究人员，政策制定者和公众。预防研究中心的总体目标：育儿阿片类药物用户（PWO中心）是为了改善受个人，家庭和社区的福祉阿片类药物危机通过关注行为（父母反应，温暖）和神经认知系统（例如，执行功能，奖励响应能力）是两者共有的基本机制成瘾问题和育儿挑战。 PWO中心的研究项目和核心是基于统一概念模型并采用转化科学方法，基础科学调查基本机制的开发和评估可扩展干预措施旨在为政策和实践带来人群级别的影响。我们的多学科调查团队有一直在研究针对具有物质使用历史家庭的家庭育儿干预措施在过去的20年中，合作和生产力具有悠久而富有成效的历史。我们有强大我们州长，我们的社区合作伙伴和我们的大学对拟议的PWO中心的支持领导。 PWO中心预期的长期公共卫生结果是改善证据 - 基于预防药物滥用，减少孕产妇滥用和成瘾，减少代际吸毒成瘾的传播，提高科学理解和公众对阿片类药物的影响的认识通过潜在的行为和神经认知机制，孕产妇的育儿习惯，下一个准备该领域的研究人员和从业人员的产生，并增加基于证据的政策。