COBRE Phase 2: Center for Neuroplasticity at the University of Puerto Rico

COBRE 第 2 阶段：波多黎各大学神经可塑性中心

• 批准号: 10449241
• 负责人: JOSE Antonio LASALDE-DOMINICCI
• 金额: $ 198.85万
• 依托单位: UNIVERSITY OF PUERTO RICO MED SCIENCES
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-07-01 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10449241
• 关键词: Address; Administrator; Advisory Committees; Basic Science; Benchmarking; Biomedical Research; Centers of Research Excellence; Communities; Core Facility; Coupled; Development; Economic Development; Educational workshop; Electrophysiology (science); Ensure; Environment; Evolution; Faculty; Familiarity; Fostering; Funding; Goals; Government; Grant; Growth; Homeostasis; Image; Infrastructure; Institutes; Institution; Investigation; Investments; Island; Laboratories; Lasers; Leadership; Manuscripts; Medical; Mentors; Mentorship; Microscope; Modernization; Molecular; Neurobiology; Neuronal Plasticity; Neurons; Neurosciences; Organizational Objectives; Pathway interactions; Phase; Piedra; Pilot Projects; Play; Positioning Attribute; Preparation; Private Sector; Property; Puerto Rico; Recording of previous events; Records; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Training; Science; Scientist; Series; Site; System; Training; Training Programs; Translational Research; United States National Institutes of Health; Universities; Writing; base; biomedical resource; career; career development; design; experience; industry partner; innovation; instrument; instrumentation; interdisciplinary collaboration; interest; knowledge base; member; neuroimaging; operation; programs; residence; symposium; synergism

The University of Puerto Rico (UPR) Medical Sciences Campus proposes to sustain and expand its COBRE Center for Neuroplasticity. The second phase of Center operation will significantly strengthen the research infrastructure of the institution and will impact biomedical investigation throughout the island. The specific aims of the COBRE Center for Neuroplasticity at the University of Puerto Rico are: 1) Foster development of junior investigators into competitive researchers working on projects with direct biomedical significance. Our Phase I intensive mentoring program will be further strengthened with the goal of continued development of a competitive research culture; 2) Maintain and augment the NeuroImaging and Electrophysiology Facility (NIEF) established under COBRE Phase I. This multi-site core facility provides state-of-the-art instrumentation, training, and expertise to the research community of Puerto Rico. The NIEF is centered at the Molecular Sciences Research Center (MSRC) a major UPR infrastructure investment that is strategically positioned to enhance collaborative efforts between the major UPR campuses. The MSRC also serves numerous institutions associated with partnering IDeA Networks of Biomedical Research Excellence (INBRE); 3) Support programmatic activities (COBRE Seminar Series, Annual Puerto Rico Neuroscience Conference, COBRE Symposia, Workshops) that increase interdisciplinary collaborations at the basic research level. It is anticipated that these activities will significantly strengthen the entire biomedical research infrastructure and will stimulate collaborative investigation leading to translational research projects. The major strengths of this proposed COBRE Phase II initiative include: 1) the Program Director, who is both an accomplished researcher with extensive funding and advisory activities within the NIH and an experienced administrator with a history of successful initiation of research and training programs; 2) an experienced and effective Administrative Core; 3) a team of young, aggressive and highly committed early career scientists; 4) deployment of the new MSRC as a centralized hub for integrated and collaborative research; 5) the full commitment of the UPR Administration toward assuring the stated goals of the project. The COBRE Center for Neuroplasticity at the University of Puerto Rico is defining pathways and benchmarks for basic and translational research across the UPR system. Its second phase will ensure the sustained growth and evolution of a program that will advance the trajectory of competitive biomedical research in Puerto Rico over the next decades.

波多黎各大学（UPR）医学科学校园建议维持和 扩展其神经可塑性的毛cen中心。中心操作的第二阶段将 显着加强机构的研究基础设施，并将影响生物医学 整个岛上的调查。毛绒神经塑性中心的具体目的 波多黎各大学的是：1）促进初级调查人员的发展 竞争性的研究人员从事具有直接生物医学意义的项目的工作。我们的第一阶段 持续的目标将进一步加强密集的指导计划 发展竞争性研究文化； 2）维护和增加神经影像学和 电生理设施（nief）在山脉阶段I中建立。此多站点核心设施 为研究社区提供最先进的仪器，培训和专业知识 波多黎各。胸部以分子科学研究中心（MSRC）为中心 主要的UPR基础设施投资，在战略上定位以增强协作 主要UPR校园之间的努力。 MSRC还为众多机构服务 与卓越生物医学研究的合作思想网络相关（INBRE）； 3） 支持计划活动（COBRE研讨会系列，年度波多黎各神经科学 会议，山脉研讨会，研讨会），增加了跨学科合作 基础研究水平。预计这些活动将大大增强整个 生物医学研究基础设施，并将刺激协作调查 翻译研究项目。该提议的索布雷II期计划的主要优势 包括：1）计划主任，他都是一位有成就的研究员 NIH内的资金和咨询活动，以及经验丰富的管理员 成功启动研究和培训计划； 2）经验丰富且有效的 行政核心； 3）一支年轻，积极进取且致力于早期职业的团队 科学家； 4）部署新的墨西哥委员会作为集成和协作的集中式枢纽 研究; 5）UPR政府对确保既定目标的全部承诺 项目。波多黎各大学的神经塑性中心正在定义 UPR系统的基础和翻译研究的途径和基准。它是 第二阶段将确保计划的持续增长和演变，以提高 在接下来的几十年中，波多黎各的竞争性生物医学研究轨迹。