Administrative Core

行政核心

• 批准号: 10729384
• 负责人: ANDREA CALIFANO
• 金额: $ 5.4万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-19 至 2028-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10729384
• 关键词: Address; Administrator; Advisory Committees; Award; Biomedical Research; Budgets; Calibration; Cancer Center; Cities; Collaborations; Collection; Committee Members; Communication; Communities; Complex; Computer software; Consultations; Data; Data Set; Decision Making; Education; Educational workshop; Elements; Ensure; Environment; Evaluation; Feedback; Fostering; Funding; Funding Opportunities; Future; Grant; Guidelines; High Performance Computing; Human Resources; Individual; Knowledge; Leadership; Learning; Logistics; Maintenance; Malignant Neoplasms; Minority-Serving Institution; Monitor; New York City; Organization administrative structures; Persons; Pilot Projects; Policies; Preparation; Procedures; Process; Progress Reports; Qualifying; Research; Research Infrastructure; Research Personnel; Research Project Grants; Resource Sharing; Resources; Services; Shapes; Site Visit; Structure; System; Systems Biology; Technology; Teleconferences; Therapeutic; United States National Institutes of Health; Work; analytical tool; data harmonization; data sharing; data submission; diversity and inclusion; high school; meetings; member; operation; outreach; programs; recruit; repository; success; synergism; university student; web site; working group

PROJECT SUMMARY The Administrative Core will provide coordination and oversight across all Center activities. It will help maximize interactions and synergies and will enable optimal use of available research infrastructure, including Core resources and services, and a state-of-the-art high-performance computing environment. It will also facilitate participation of CaST members to CSBC activities, ensure that programmatic feedback from the CSBC is integrated into the Center’s operations, and administer the one-year intra-Center pilot research projects. An effective management structure will be put in place to ensure that the Center’s complex objectives are achieved in timely fashion, including an Executive Steering Committee (ESC) —comprising the Center’s Directors, Center Administrator, Project/Core Leads, and NCI program officers—which will oversee the Center’s operations and provide overall guidance to the investigators; a Center Administrator who will meet frequently with Project and Core leads to track progress on project activities, facilitate interactions and integration between Projects, and ensure that the decisions made at the ESC meetings are properly communicated; and a Data Manager who will ensure that resources and data generated by the Center are consistently annotated and prepared for submission to NIH repositories in a timely and effective manner. The ESC will meet quarterly to candidly assess Project progress, address operational and research issues that require corrective action, prioritize use of Center resources, make decision about Pilot Project awards, and ensure coordination with related NCI and NIH activities. The Administrative Core will provide logistical support for the annual NCI site visit, coordinate preparation of progress reports, monitor compliance with regulatory requirements, and provide timely fiscal reviews and budget analysis. In support of these efforts, the Core will define and track a broad collection of quantitative metrics to assess the quality and utility of Center deliverables. The Core will be responsible for assembling a world class scientific External Advisory Committee (EAB) to advise the Center’s co-Directors and to provide an impartial assessment of the Center’s research program. In addition to ad hoc communications, the EAB members will meet in person once a year at the Center’s NCI site visit, where they will attend scientific presentations from Project and Core investigators and will offer feedback on research progress and future directions, as well as advice on program management and the administration of the Pilot Project program. The Administrative Core will coordinate the participation of Center personnel to all Consortium activities, including attending meetings and workshops, contributing to working groups and technical committees, and interfacing with other NIH initiatives. Finally, it will support a broad educational program implemented through the Outreach core, aiming to expand inclusivity and diversity in Cancer Systems Biology by offering education and learning opportunities to underprivileged high school and college students from minority-serving institutions in New York City and other big cities.

项目概要 行政核心将为中心的所有活动提供协调和监督，这将有助于最大限度地发挥作用。 相互作用和协同作用，并将实现现有研究基础设施的最佳利用，包括核心 资源和服务以及最先进的高性能计算环境也将促进这一点。 CaST 成员参与 CSBC 活动，确保 CSBC 的计划性反馈得到落实 融入中心的运营，并管理为期一年的中心内试点研究项目。 将建立有效的管理结构，以确保实现中心的复杂目标 及时，包括执行指导委员会（ESC）——由中心主任、中心 管理员、项目/核心领导和 NCI 项目官员——他们将监督中心的运营和 为研究人员提供全面指导；中心管理员将经常与项目和 核心领导跟踪项目活动的进展，促进项目之间的互动和集成，以及 确保 ESC 会议上做出的决定得到适当传达，并由一名数据经理负责； 确保中心生成的资源和数据得到一致的注释和准备提交 ESC 将每季度召开一次会议，对项目进行及时有效的评估。 进展，解决需要纠正行动的运营和研究问题，优先使用中心 资源，做出有关试点项目奖励的决定，并确保与相关 NCI 和 NIH 的协调 行政核心将为每年的 NCI 现场访问提供后勤支持，并进行协调。 准备进度报告，监控监管要求的遵守情况，并及时提供财务信息 为了支持这些工作，核心将定义和跟踪广泛的集合。 核心部门将负责评估中心可交付成果的质量和效用的定量指标。 组建世界一流的科学外部咨询委员会（EAB），为中心的联合主任和 除了临时沟通之外，还对中心的研究计划进行公正的评估。 EAB 成员将每年在该中心的 NCI 实地考察中亲自会面一次，在那里他们将参加科学活动 项目和核心研究人员的演讲，并将提供有关研究进展和未来的反馈 指导以及有关项目管理和试点项目管理的建议。 行政核心将协调中心人员参与所有联盟活动，包括 参加会议和研讨会，为工作组和技术委员会做出贡献，并进行交流 最后，它将支持通过外展实施的广泛教育计划。 核心，旨在通过提供教育和学习来扩大癌症系统生物学的包容性和多样性 为纽约少数族裔服务机构的贫困高中生和大学生提供机会 市等大城市。