Administrative Core

行政核心

• 批准号: 10729384
• 负责人: ANDREA CALIFANO
• 金额: $ 5.4万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-19 至 2028-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10729384
• 关键词: Address; Administrator; Advisory Committees; Award; Biomedical Research; Budgets; Calibration; Cancer Center; Cities; Collaborations; Collection; Committee Members; Communication; Communities; Complex; Computer software; Consultations; Data; Data Set; Decision Making; Education; Educational workshop; Elements; Ensure; Environment; Evaluation; Feedback; Fostering; Funding; Funding Opportunities; Future; Grant; Guidelines; High Performance Computing; Human Resources; Individual; Knowledge; Leadership; Learning; Logistics; Maintenance; Malignant Neoplasms; Minority-Serving Institution; Monitor; New York City; Organization administrative structures; Persons; Pilot Projects; Policies; Preparation; Procedures; Process; Progress Reports; Qualifying; Research; Research Infrastructure; Research Personnel; Research Project Grants; Resource Sharing; Resources; Services; Shapes; Site Visit; Structure; System; Systems Biology; Technology; Teleconferences; Therapeutic; United States National Institutes of Health; Work; analytical tool; data harmonization; data sharing; data submission; diversity and inclusion; high school; meetings; member; operation; outreach; programs; recruit; repository; success; synergism; university student; web site; working group

PROJECT SUMMARY The Administrative Core will provide coordination and oversight across all Center activities. It will help maximize interactions and synergies and will enable optimal use of available research infrastructure, including Core resources and services, and a state-of-the-art high-performance computing environment. It will also facilitate participation of CaST members to CSBC activities, ensure that programmatic feedback from the CSBC is integrated into the Center’s operations, and administer the one-year intra-Center pilot research projects. An effective management structure will be put in place to ensure that the Center’s complex objectives are achieved in timely fashion, including an Executive Steering Committee (ESC) —comprising the Center’s Directors, Center Administrator, Project/Core Leads, and NCI program officers—which will oversee the Center’s operations and provide overall guidance to the investigators; a Center Administrator who will meet frequently with Project and Core leads to track progress on project activities, facilitate interactions and integration between Projects, and ensure that the decisions made at the ESC meetings are properly communicated; and a Data Manager who will ensure that resources and data generated by the Center are consistently annotated and prepared for submission to NIH repositories in a timely and effective manner. The ESC will meet quarterly to candidly assess Project progress, address operational and research issues that require corrective action, prioritize use of Center resources, make decision about Pilot Project awards, and ensure coordination with related NCI and NIH activities. The Administrative Core will provide logistical support for the annual NCI site visit, coordinate preparation of progress reports, monitor compliance with regulatory requirements, and provide timely fiscal reviews and budget analysis. In support of these efforts, the Core will define and track a broad collection of quantitative metrics to assess the quality and utility of Center deliverables. The Core will be responsible for assembling a world class scientific External Advisory Committee (EAB) to advise the Center’s co-Directors and to provide an impartial assessment of the Center’s research program. In addition to ad hoc communications, the EAB members will meet in person once a year at the Center’s NCI site visit, where they will attend scientific presentations from Project and Core investigators and will offer feedback on research progress and future directions, as well as advice on program management and the administration of the Pilot Project program. The Administrative Core will coordinate the participation of Center personnel to all Consortium activities, including attending meetings and workshops, contributing to working groups and technical committees, and interfacing with other NIH initiatives. Finally, it will support a broad educational program implemented through the Outreach core, aiming to expand inclusivity and diversity in Cancer Systems Biology by offering education and learning opportunities to underprivileged high school and college students from minority-serving institutions in New York City and other big cities.

项目摘要 行政核心将在所有中心活动中提供协调和监督。它将有助于最大化 互动和协同作用，并将能够最佳使用可用的研究基础设施，包括核心 资源和服务，以及最先进的高性能计算环境。这也将有助于 演员参与CSBC活动，确保CSBC的程序反馈是 集成到该中心的运营中，并管理一年中的中心试点研究项目。一个 将建立有效的管理结构，以确保实现中心的复杂目标 及时的方式，包括执行指导委员会（ESC） - 建立该中心的董事，中心 管理员，项目/核心线索和NCI计划官员将监督该中心的运营和 向调查人员提供总体指导；中心管理员将经常与项目会面 核心导致跟踪项目活动的进度，促进项目之间的互动和集成，以及 确保正确沟通在ESC会议上做出的决定；还有一个数据经理 确保对中心产生的资源和数据一致地注释并准备提交 及时有效地向NIH存储库。 ESC将每季度开会候选项目 进步，解决需要采取纠正措施，优先使用中心的操作和研究问题 资源，对试点项目奖的决定，并确保与相关NCI和NIH协调 活动。行政核心将为年度NCI现场访问提供后勤支持，协调 准备进度报告，监控符合监管要求，并提供及时的财政 评论和预算分析。为了支持这些努力，核心将定义和跟踪广泛的集合 定量指标以评估中心可交付成果的质量和实用性。核心将负责 组建世界一流的科学外部咨询委员会（EAB），以建议中心的联合主任和 提供对中心研究计划的公正评估。除了临时通信外， EAB成员每年将在中心的NCI现场访问中亲自见面，他们将参加科学 项目和核心调查人员的演讲，并将提供有关研究进度和未来的反馈 方向以及有关计划管理和试点项目计划的建议。这 行政核心将协调中心人员参加所有财团活动，包括 参加会议和研讨会，为工作组和技术委员会做出贡献以及接口 与其他NIH计划。最后，它将支持通过外展实施的广泛教育计划 核心，旨在通过提供教育和学习来扩大癌症系统生物学的包容性和多样性 纽约少数派服务机构的高中和大学生的机会 城市和其他大城市。