Palliative Care Research Cooperative Group (PCRC): Project Coordinating Center

姑息治疗研究合作小组 (PCRC)：项目协调中心

• 批准号: 10438796
• 负责人: JEAN S KUTNER
• 金额: $ 82.56万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-28 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10438796
• 关键词: Achievement; Address; Advisory Committees; Award; Businesses; Caregiver research; Childhood; Clinical Research; Clinical Trials; Collaborations; Communication; Data; Development; Economically Deprived Population; Funding; Goals; Grant; Informatics; Infrastructure; Institutional Review Boards; Intention; Investments; Logistics; Marketing; Measurement; Methodological Studies; Methods; Monitor; Multi-Institutional Clinical Trial; Occupational activity of managing finances; Outcome; Palliative Care; Performance; Phase; Population; Principal Investigator; Process; Productivity; Reporting; Research; Research Personnel; Research Support; Resources; Science; Site; Special Population; Standardization; Structure; Support Groups; Training; Underrepresented Minority; United States National Institutes of Health; data de-identification; data management; data repository; multiple chronic conditions; operation; recruit; statistics; study population; success; tool

PROJECT SUMMARY/ABSTRACT The primary goals of this U2C application are to increase the productivity and impact of the Palliative Care Research Cooperative Group (PCRC), facilitating the conduct of high-quality, effective clinical research, and expanding the number and expertise of palliative care researchers in conducting multi-site clinical trials. In pursuit of these overall goals and objectives, the Project Coordinating Center (PCC), one of two Centers within the PCRC, strives to refine and enhance replicable and scalable infrastructure, processes, tools, and methods, including evaluative metrics, to support efficient and effective cooperative group function. The PCC's specific aims are to: (1) provide organizational infrastructure to the PCRC, including efficient administrative, financial, regulatory, and data management functions as well as tracking and monitoring of PCRC performance and outcomes; (2) manage day-to-day operations of the PCRC with respect to cooperative group functions and processes, while developing replicable, standardized, quality-assured, operational methods and tools; (3) serve as a central coordinating hub for PCRC Cores, Centers, investigators and sites, with responsibility for communications, liaison activities, administrative support and integration of relevant efforts and functions; and (4) develop research capacity at PCRC sites and among PCRC investigators by supporting investigators and sites throughout the continuum from study development through study conduct and, when completed, transfer of de-identified data to the PCRC Data Repository. Through new or expanded initiatives, such as supporting investigators to comply with new NIH single IRB requirements for multi-site studies, tracking and supporting investigators' compliance with new and evolving clinical trial requirements (in partnership with the Investigator Development Center), and supporting recruitment and retention of diverse study populations, the PCC provides an efficient and effective support structure for the PCRC and its investigators.

项目摘要/摘要 该U2C应用的主要目标是提高姑息治疗的生产率和影响 研究合作集团（PCRC），促进了高质量，有效临床研究的行为 扩大姑息治疗研究人员在进行多站点临床试验中的数量和专业知识。在 追求这些总体目标和目标，项目协调中心（PCC）是其中的两个中心之一 PCRC努力完善并增强可复制和可扩展的基础架构，过程，工具和方法， 包括评估指标，以支持高效有效的合作组功能。 PCC的具体 目的是：（1）向PCRC提供组织基础架构，包括有效的行政，财务， 监管，数据管理功能以及PCRC性能的跟踪和监视 结果； （2）管理PCRC的日常操作在合作组功能方面 过程，同时开发可复制，标准化，质量保证的操作方法和工具； （3） 充当PCRC核心，中心，调查人员和站点的中央协调枢纽，负责 沟通，联络活动，行政支持和相关努力和职能的整合；和 （4）通过支持研究人员和 从研究开发到研究行为的整个连续性站点，完成后，转移 将识别数据的数据存储库的去识别数据。通过新的或扩展的计划，例如支持 调查人员符合新的NIH单一IRB要求多站点研究，跟踪和支持 研究人员遵守新的和不断发展的临床试验要求（与研究者合作 开发中心），并支持招聘和保留多样化的研究人群，PCC 为PCRC及其研究人员提供有效的支持结构。