Palliative Care Research Cooperative Group (PCRC): Refinement and Expansion

姑息治疗研究合作小组 (PCRC)：细化和扩展

基本信息

批准号：
10331658
负责人：
JEAN S KUTNER
金额：
$ 21.77万
依托单位：
UNIVERSITY OF COLORADO DENVER
依托单位国家：
美国
项目类别：
财政年份：
2013
资助国家：
美国
起止时间：
2013-09-28 至 2023-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10331658
关键词：
Address Administrative Coordination Affect Age American Award Awareness Behavioral COVID-19 COVID-19 pandemic COVID-19 vaccination COVID-19 vaccine Caregiver research Caregivers Caring Clinical Clinical Research Cohort Studies Color Communication Communities Consultations Contracts Data Decision Making Development Disincentive Economics Enrollment Environment Epidemic Ethics Extended Family Face Family Female Foundations Funding Generations Goals Grant Health Health Campaign Health behavior Healthcare Hearing Home Home Health Aides Hospice Care Hospitals Immigrant Incentives Individual Informatics Infrastructure Internships Interview Measurement Medical Methodological Studies Methodology Minority Groups Modeling Multi-Institutional Clinical Trial National Institute of Nursing Research Neighborhoods New York City Nurses Palliative Care Patients Persons Pharmacists Physicians Policies Population Population Heterogeneity Poverty Process Productivity Public Health Quality of life Research Research Activity Research Personnel Risk Role SARS-CoV-2 infection SARS-CoV-2 transmission Science Site Source Structure Travel Trust Underrepresented Populations Underserved Population Vaccination Voice Vulnerable Populations Woman Work adverse outcome base care seeking community engagement community organizations data privacy data repository end of life ethnic minority population experience federal poverty level health literacy high risk hospice environment improved influenza virus vaccine insight multi-site trial multidisciplinary pandemic disease peer personal protective equipment racial minority research study skills social social vulnerability socioeconomics statistics therapy design training opportunity uptake vaccine hesitancy

项目摘要

PROJECT SUMMARY/ABSTRACT End of life and palliative care (EOLPC) seeks to enhance quality of life for those with serious illness and their caregivers. The need for and delivery of EOLPC have far exceeded the research that provides evidence of best practices. Small, single-site trials, unrepresentative study cohorts, and studies lacking sufficient rigor hamper provision of high-quality EOLPC. While other fields have advanced their evidence through large, diverse, multi-site trials, EOLPC research has been impeded by an insufficient infrastructure and scientific workforce. The primary goals of this U2C application are to increase the productivity and impact of the Palliative Care Research Cooperative Group (PCRC), its ability to facilitate the conduct of high-quality, effective clinical research, and to expand the number and expertise of palliative care researchers in conducting multi-site clinical trials. The PCRC strives to advance the science of EOLPC by providing investigators with the broad range of support necessary to conduct large scale, multi-site clinical trials and other research studies. This support includes training opportunities, pilot grant awards, access to a large, centralized repository of data from EOLPC studies, methodologic consultation, administrative coordination of research activities, and access to a large network of potential study enrollment sites. Structurally, the PCRC consists of six synergistic components, each led by a senior EOLPC researcher. The Project Coordinating Center coordinates overall administration of the PCRC. The Investigator Development Center builds the skills of EOLPC researchers. Four Cores provide methodological expertise: Data, Informatics, and Statistics; Measurement; Caregiver Research; and Clinical Studies/Methodology. The U2C PCRC application addresses Scientific, Operational, Capacity- building, and Collaborative Aims. By accomplishing these aims, the PCRC will expand its ability to support a robust community of interdisciplinary EOLPC researchers who address topics that guide the delivery of palliative care with an ultimate goal of improving the lives of patients with serious illness and their caregivers.

项目摘要/摘要生命的尽头和姑息治疗（EOLPC）试图提高认真的人的生活质量疾病及其护理人员。 EOLPC的需求和交付远远超出了提供最佳实践证据的研究。小型单点试验，无代表性研究队列，以及缺乏足够严格的障碍物提供高质量EOLPC的研究。尽管其他领域通过大型，多样的多站点试验提出了证据，但EOLPC 基础设施和科学劳动力不足阻碍了研究。这 U2C应用的主要目标是提高姑息治疗的生产率和影响护理研究合作小组（PCRC），其促进高质量行为的能力，有效的临床研究，并扩大姑息治疗的数量和专业知识进行多站点临床试验的研究人员。 PCRC努力推进科学 EOLPC通过为调查人员提供进行大型支持所需的广泛支持尺度，多站点临床试验和其他研究。此支持包括培训机会，试点赠款奖，从EOLPC获得大型的集中数据存储库研究，方法学咨询，研究活动的行政协调以及访问大型潜在研究入学地点网络。在结构上，PCRC由六个协同组件，每个组件由EOLPC高级研究员领导。项目协调中心协调PCRC的总体给药。调查员开发中心建立EOLPC研究人员的技能。四个核心提供方法论专业知识：数据，信息学和统计数据；测量;照顾者研究；和临床研究/方法论。 U2C PCRC应用程序涉及科学，运营，能力 - 建筑物和协作目标。通过实现这些目标，PCRC将扩大其能力支持一个强大的跨学科EOLPC研究人员社区，他们讨论了这些主题指导提供姑息治疗的最终目标是改善患者的生活严重疾病及其护理人员。