The Utah Regional Network for Excellence in Neuroscience Clinical Trials

犹他州神经科学临床试验卓越区域网络

基本信息

批准号：
9293398
负责人：
John Robinson Singleton
金额：
$ 29.8万
依托单位：
UNIVERSITY OF UTAH
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
起止时间：
2011-09-30 至 2018-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9293398
关键词：
Academia Address Adult Affect Arizona Basic Science Biological Products Caring Child Childhood Cities Clinical Clinical Research Clinical Sciences Clinical Trials Clinical Trials Design Clinical Trials Network Collaborations Colorado Communities Complex Country Development Disease Education Ensure Environment Face Faculty Foundations Funding Goals Healthcare Hospitals Human Resources Human Subject Research Hydrocephalus Industry Institutional Review Boards International Knowledge Laboratories Leadership Medical center Mentors Mentorship Modeling Molecular Neurobiology Montana National Institute of Neurological Disorders and Stroke Nervous system structure Neurologic Neurologist Neurology Neuropathy Neuropsychology Neurosciences Neurosciences Research Nevada Patients Pediatric Neurology Performance Pharmacologic Substance Population Population Sciences Positioning Attribute Public Relations Rare Diseases Recruitment Activity Research Research Infrastructure Research Personnel Research Project Grants Resources Site Sodium Chloride Spinal Training Training and Education Translational Research Translations United States Department of Veterans Affairs United States National Institutes of Health Universities Utah Validation base biomarker development biomedical referral center career development cost effective design education research epidemiology study experience faculty support health care delivery impaired glucose tolerance innovation interest medical schools member nervous system disorder neurosurgery novel novel therapeutics skills social media success therapeutic target trial design

项目摘要

DESCRIPTION (provided by applicant): In spite of unparalleled opportunities to assess novel therapies for both common and rare neurological disorders, investigators involved in multicenter clinical trials face an increasing array of challenges in efficiently designing, powering and performing such trials. The Network of Excellence in Neuroscience Clinical Trials (NEXT) is intended to help address this increasingly complex environment and facilitate an efficient robust mechanism for multicenter neuroscience trials via the creation of centralized infrastructure supporting a nationalized network of high quality sites and coordinating centers. Based at the University of Utah, the Utah Regional Network for Excellence in Neuroscience Clinical Trials (UR-NEXT) will provide an ideal mechanism for coordinating recruitment and access throughout a 5 state region in the Intermountain West. The coordinated efforts of a leadership team with a track record of collaboration and experience in both pediatric and adult clinical studies and trial and an experienced clinical trials manager will ensure the performance of high quality neuroscience trials across a broad range of diseases. The UR-NEXT will be centered at the University of Utah, where longstanding and close partnerships exist between the Clinical Neuroscience Center, the only integrated neuroscience center in a 5 state region, the Salt Lake City Veteran's Administration Medical Center, the western anchor for the Rocky Mountain Region, and Primary Children's Medical Center (PCMC), the leading pediatric referral center for the region. UR-NEXT will additionally benefit from an established network of referring community neurologists with interest in clinical trials, the Western Intermountain Neurological Organization (WINO), which has members ranging from southern Utah to Montana, and Nevada to western Colorado. The Neurology Department has sections in each major subspecialty and substantial expertise in the management and performance of both adult and pediatric multicenter clinical trials. The UR-NEXT will benefit from the Center for Clinical and Translational Science as well as numerous other collaborative resources. Overall, the network has primary access to a population of approximately 8 million covered lives, making it the ideal choice for a NEXT site for this region.

描述（由申请人提供）：尽管有无与伦比的机会来评估常见和罕见神经系统疾病的新疗法，但参与多中心临床试验的研究人员在有效地设计，动力和执行此类试验方面面临着越来越多的挑战。神经科学临床试验的卓越网络（下一个）旨在帮助解决这个日益复杂的环境，并通过建立集中的基础设施来支持高质量站点和协调中心的国有化网络，从而促进多中心神经科学试验的有效鲁棒机制。位于犹他大学的犹他州神经科学临床试验卓越区域网络（UR-NEXT）将提供一个理想的机制，可为整个5个州Intermountmountmountmountmount Mountmount Mountermount Mountermount Mounterment Mentermount Mountermount Mountermount Mounterment the Intermount Mountmountmount Mountmount Mountmount Mountermount Mentermount Mentermount Mentermount Menterment临床试验（UR-NEXT）提供了理想的机制。领导团队的协调努力在儿科和成人临床研究和试验中具有协作和经验的记录以及经验丰富的临床试验经理将确保在广泛的疾病中进行高质量的神经科学试验。 UR-NEXT将集中在犹他大学，那里的临床神经科学中心之间存在长期和密切的合作伙伴关系，临床神经科学中心是盐湖城老兵管理医疗中心唯一一个综合的神经科学中心，这是盐湖城的西方医疗中心，这是西方的主持人。落基山地区和主要儿童医疗中心（PCMC）是该地区领先的小儿推荐中心。 Ur-Next将从既定的社区神经科医生，对临床试验感兴趣的社区神经科医生，西部神经系统（Wino）（Wino）中受益，该网络的成员从犹他州南部到蒙大拿州以及内华达州到西科罗拉多州。神经病学部门在每个主要的亚专业中都有各个部分，并且在成人和小儿多中心临床试验的管理和性能方面具有丰富的专业知识。 UR-NEXT将受益于临床和转化科学中心以及许多其他协作资源。总体而言，该网络主要可以访问约800万的人口，这是该地区下一个地点的理想选择。