Integrative Training in Oncogenic Signaling

致癌信号综合培训

• 批准号: 9312769
• 负责人: Philip H Howe
• 金额: $ 31.8万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-08 至 2021-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9312769
• 关键词: Oncogenic; Signal Transduction; Training

PROJECT SUMMARY/ABSTRACT This proposal seeks National Cancer Institute (NCI) support for an exciting new Integrative Training in Oncogenic Signaling (ITOS) Program that has been developed by a select group of cancer scientists affiliated with the Hollings Cancer Center (HCC) at the Medical University of South Carolina (MUSC). The ITOS Program takes place in this active and growing medical center environment with state-of-the-art facilities, a vibrant NCI-designated cancer center, and an active Office of Postdoctoral Affairs. Led by a Program Director with an exceptionally strong cancer research background and leadership experience, the ITOS Program will select and support the placement of trainees in experienced, well-funded, productive laboratories led by the Program Faculty who reside in an interactive, multi-departmental research environment with extensive resources. Each trainee will have a primary mentor and one or two secondary mentors with complementary expertise to ensure distinct and valuable perspectives that will enhance the overall cancer-related research training experience. The objectives of this training program are to provide proactive mentoring and oversight and research training in cutting-edge methodology; to develop useful academic and essential career development skills; to foster collaborative, interdisciplinary interactions with faculty and other trainees; and to provide exposure to current cancer research discoveries and how these are being translated into novel approaches to prevention, diagnosis, and treatment of cancer. Slated to train five postdoctoral trainees each year for five years, this robust training opportunity has seven programmatic components essential in obtaining the aforementioned objectives. These include the following components: 1) 33 Program Faculty who share common interests in cancer research and will provide the essential mentoring for trainees; 2) one to two year experiences in Program Faculty laboratories found within the vibrant HCC research environment; 3) an ITOS Program Research Club providing an engaging community forum for the trainees and Program Faculty to discuss work in progress as well as the latest discoveries in cancer science; 4) shared research resource workshops and tailored training with experts in cutting-edge biotechnologies; 5) interdisciplinary engagement with trainees in HCC-sponsored thematic research retreats, symposia, work in progress meetings, and seminars; 6) career development workshops and courses that will equip trainees for independent success; and 7) opportunities to network nationally at a minimum of two professional conferences each year. In summary, the ITOS Program will offer distinct experiences and opportunities only afforded to the selected ITOS Fellows, and the program, led by an outstanding cadre of Program Faculty, is anticipated to be highly attractive to emerging junior investigators locally and nationally.

项目摘要/摘要 该建议寻求国家癌症研究所（NCI）支持激动人心的新综合培训 由一组癌症科学家制定的致癌信号传导（ITOS）计划 与南卡罗来纳州医科大学（MUSC）的Hollings癌症中心（HCC）一起。 ITOS 计划在这个活跃而不断增长的医疗中心环境中进行，最先进的设施， 充满活力的NCI指定的癌症中心，以及博士后事务的积极办公室。由计划主管领导 ITOS计划将具有异常强大的癌症研究背景和领导经验，将 选择并支持受训者在经验丰富，资金充足，高产的实验室中的位置 居住在互动，多部门研究环境中的计划教师 资源。每个学员将有一个主要导师和一两个次级导师，并具有互补的 专业知识以确保独特而有价值的观点，以增强与癌症相关的整体研究 培训经验。该培训计划的目标是提供积极的指导和监督 和最先进方法论的研究培训；发展有用的学术和基本职业 发展技能；为了促进合作，与教师和其他学员的跨学科互动；然后 提供当前的癌症研究发现，以及如何将其转化为新颖 预防，诊断和治疗癌症的方法。 这个强大的训练机会计划每年培训五名博士后学员，有7个 获得上述目标必不可少的程序组件。这些包括以下 组成部分：1）33计划教师，他们在癌症研究中具有共同利益，并将提供 对学员的基本指导； 2）在计划中发现的一到两年的课程教师实验室经验 充满活力的HCC研究环境； 3）ITOS计划研究俱乐部，提供引人入胜的社区 学员和计划教师的论坛讨论正在进行的工作以及最新发现 癌症科学； 4）共享研究资源研讨会和量身定制的培训 生物技术； 5）跨学科与受训者在HCC赞助的主题研究务虚会中的互动， 专题讨论会，进步会议和研讨会； 6）职业发展研讨会和课程 为学员配备独立成功； 7）至少有两个人在全国建立网络的机会 每年的专业会议。总而言之，ITOS计划将提供不同的体验，并且 仅给选定的ITOS研究员提供的机会，该计划由一个出色的干部领导 计划教师预计将对新兴的初级调查员在本地和全国范围内具有很高的吸引力。