Integrative Training in Oncogenic Signaling

致癌信号综合培训

• 批准号: 9312769
• 负责人: Philip H Howe
• 金额: $ 31.8万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-08 至 2021-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9312769
• 关键词: Oncogenic; Signal Transduction; Training

PROJECT SUMMARY/ABSTRACT This proposal seeks National Cancer Institute (NCI) support for an exciting new Integrative Training in Oncogenic Signaling (ITOS) Program that has been developed by a select group of cancer scientists affiliated with the Hollings Cancer Center (HCC) at the Medical University of South Carolina (MUSC). The ITOS Program takes place in this active and growing medical center environment with state-of-the-art facilities, a vibrant NCI-designated cancer center, and an active Office of Postdoctoral Affairs. Led by a Program Director with an exceptionally strong cancer research background and leadership experience, the ITOS Program will select and support the placement of trainees in experienced, well-funded, productive laboratories led by the Program Faculty who reside in an interactive, multi-departmental research environment with extensive resources. Each trainee will have a primary mentor and one or two secondary mentors with complementary expertise to ensure distinct and valuable perspectives that will enhance the overall cancer-related research training experience. The objectives of this training program are to provide proactive mentoring and oversight and research training in cutting-edge methodology; to develop useful academic and essential career development skills; to foster collaborative, interdisciplinary interactions with faculty and other trainees; and to provide exposure to current cancer research discoveries and how these are being translated into novel approaches to prevention, diagnosis, and treatment of cancer. Slated to train five postdoctoral trainees each year for five years, this robust training opportunity has seven programmatic components essential in obtaining the aforementioned objectives. These include the following components: 1) 33 Program Faculty who share common interests in cancer research and will provide the essential mentoring for trainees; 2) one to two year experiences in Program Faculty laboratories found within the vibrant HCC research environment; 3) an ITOS Program Research Club providing an engaging community forum for the trainees and Program Faculty to discuss work in progress as well as the latest discoveries in cancer science; 4) shared research resource workshops and tailored training with experts in cutting-edge biotechnologies; 5) interdisciplinary engagement with trainees in HCC-sponsored thematic research retreats, symposia, work in progress meetings, and seminars; 6) career development workshops and courses that will equip trainees for independent success; and 7) opportunities to network nationally at a minimum of two professional conferences each year. In summary, the ITOS Program will offer distinct experiences and opportunities only afforded to the selected ITOS Fellows, and the program, led by an outstanding cadre of Program Faculty, is anticipated to be highly attractive to emerging junior investigators locally and nationally.

项目概要/摘要 该提案寻求美国国家癌症研究所 (NCI) 支持一项令人兴奋的新综合培训 致癌信号 (ITOS) 程序由一组选定的附属癌症科学家开发 与南卡罗来纳医科大学 (MUSC) 的霍林斯癌症中心 (HCC) 合作。信息技术操作系统 项目在这个活跃且不断发展的医疗中心环境中进行，拥有最先进的设施、 充满活力的 NCI 指定癌症中心，以及活跃的博士后事务办公室。由项目总监领导 凭借极其强大的癌症研究背景和领导经验，ITOS 计划将 选择并支持将学员安置在由以下机构领导的经验丰富、资金充足、富有成效的实验室 项目教师居住在一个互动的、多部门的研究环境中，拥有广泛的研究成果 资源。每个学员将有一名主要导师和一到两名辅助导师 专业知识，以确保独特和有价值的观点，从而增强整体癌症相关研究 培训经验。该培训计划的目标是提供主动指导和监督 以及尖端方法的研究培训；发展有用的学术和重要的职业 发展技能；促进与教师和其他学员的协作、跨学科互动；并到 提供当前癌症研究发现以及如何将这些发现转化为新发现 预防、诊断和治疗癌症的方法。 这个强大的培训机会预计在五年内每年培训五名博士后学员，其中七名 实现上述目标所必需的计划组成部分。这些包括以下内容 组成部分： 1) 33 名项目教师，他们在癌症研究方面有着共同的兴趣，并将提供 对受训者的重要指导； 2）在项目学院实验室中拥有一到两年的经验 充满活力的 HCC 研究环境； 3) ITOS 项目研究俱乐部提供了一个有吸引力的社区 学员和项目教师讨论正在进行的工作以及最新发现的论坛 癌症科学； 4）与前沿专家共享研究资源研讨会和定制培训 生物技术； 5) 在 HCC 赞助的主题研究静修中与学员进行跨学科接触， 专题讨论会、进展中会议和研讨会； 6) 职业发展研讨会和课程 帮助学员取得独立成功； 7) 至少有两次在全国建立人际网络的机会 每年召开专业会议。总之，ITOS 计划将提供独特的体验和 机会只提供给选定的 ITOS 研究员，该计划由杰出的骨干领导 预计该项目对当地和全国的新兴初级研究人员具有高度吸引力。