Program 4: Cancer Prevention and Control Program (CPC)

计划 4：癌症预防和控制计划 (CPC)

• 批准号: 9315741
• 负责人: H-H. Sherry CHOW
• 金额: $ 0.1万
• 依托单位: UNIVERSITY OF ARIZONA
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-07-01 至 2021-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9315741
• 关键词: Address; Advanced Malignant Neoplasm; Area; Arizona; Behavioral; Biological Factors; Biological Markers; Breast; Cancer Burden; Cancer Center; Cancer Center Support Grant; Cancer Control; Cancer Control Research; Cancer Survivorship; Catchment Area; Chemoprevention; Clinical Research; Collaborations; Colorectal Cancer; Education and Outreach; Ensure; Environmental Risk Factor; Epidemiology; Faculty; Fostering; Funding; Goals; Grant; Incidence; International; Intervention; Knowledge; Laboratory Research; Malignant Neoplasms; Malignant neoplasm of prostate; Manuscripts; Morbidity - disease rate; Nutraceutical; Outcome; Ovarian; Peer Review; Pharmacologic Substance; Plant Roots; Primary Prevention; Quality of life; Research; Research Activity; Research Personnel; Resource Sharing; Resources; Risk; Science; Scientific Advances and Accomplishments; Secondary Prevention; Secure; Skin Cancer; Strategic Planning; Students; Testing; Time; Translational Research; Treatment outcome; Universities; Vaccines; Woman; Work; behavior test; cancer epidemiology; cancer prevention; cancer risk; cancer site; cancer type; design; gene environment interaction; improved; lifestyle factors; member; mortality; multidisciplinary; named group; novel chemoprevention; programs; psychosocial; research study; synergism; tertiary prevention

Project Summary / Abstract: Cancer Prevention and Control Program (CPC) The scientific goal of the Cancer Prevention and Control Program (CPC) at the University of Arizona Cancer Center (UACC) is to develop and implement highly interactive, multidisciplinary cancer prevention and control research, training, and outreach that will lead to progressive reductions in cancer incidence, morbidity, and mortality. The CPC fosters high impact, interactive, multidisciplinary and translational science, as well as training and outreach, that serves the catchment area of southern Arizona. Program activities are organized under three major themes: Theme 1) Cancer Epidemiology; Theme 2) Chemoprevention and Biomarkers; Theme 3) Behavioral, Psychosocial, and Quality of Life. The CPC has three Specific Aims that are aligned with these themes: Aim 1) To advance cancer prevention knowledge and inform on interventions through epidemiological science focused on biological, environmental, and lifestyle factors as well as gene- environment interactions associated with cancer risk, morbidity, and mortality; Aim 2) To evaluate novel chemoprevention compounds and biomarkers that will impact cancer prevention through focus on pharmaceuticals, nutraceuticals, and vaccines; and Aim 3) To test behavioral, psychosocial, and quality of life targeted interventions with high potential to reduce risk and improve cancer outcomes. Researchers operationalize their efforts through interdisciplinary teams largely organized by cancer type to integrate cutting- edge research activities across the continuum of cancer prevention and control and to address special populations and cancer burdens in the catchment area. The Program has 61 Members that span 21 academic departments. The Leaders of the Program utilize extensive strategic planning engaging faculty, students, and Shared Resource Directors to ensure that the Members of the Program have timely access to the resources and scientific approaches needed to advance their research goals. As of September 1, 2015, the CPC Program secured $17M in total annual grant dollars with $7.3M of that from NCI and $6.4M in other peer- reviewed funding. CPC Members contributed to 570 cancer-relevant manuscripts, of which 37% were intra- programmatic and 22% were inter-programmatic. The ability to achieve the scientific goals of the CPC Program is rooted in the Program's strong interaction among CPC members and with other UACC Programs as well as its national and international collaborations.

项目摘要/摘要：癌症预防和控制计划 (CPC) 亚利桑那大学癌症预防和控制计划 (CPC) 的科学目标 中心（UACC）旨在制定和实施高度互动、多学科的癌症预防和控制 研究、培训和推广将导致癌症发病率、发病率和死亡率的逐步降低 死亡。中国共产党致力于培养具有高影响力、互动性、多学科性和转化性的科学，以及 培训和外展，服务于亚利桑那州南部的集水区。计划活动有组织 三大主题：主题1）癌症流行病学；主题2）化学预防和生物标志物； 主题 3) 行为、社会心理和生活质量。中国共产党有三个具体目标 这些主题： 目标 1) 通过以下方式提高癌症预防知识并提供干预措施信息： 流行病学侧重于生物、环境和生活方式因素以及基因 与癌症风险、发病率和死亡率相关的环境相互作用；目标 2) 评价小说 化学预防化合物和生物标志物将通过关注影响癌症预防 药品、营养品和疫苗；目标 3) 测试行为、心理和生活质量 有针对性的干预措施具有降低风险和改善癌症结果的巨大潜力。研究人员 通过主要按癌症类型组织的跨学科团队来实施他们的努力，以整合切割 贯穿癌症预防和控制连续性的边缘研究活动，并解决特殊问题 流域内的人口和癌症负担。该计划有 61 名成员，涵盖 21 个学术领域 部门。该计划的领导者利用广泛的战略规划，吸引教师、学生和 共享资源总监，确保计划成员能够及时访问资源 以及推进其研究目标所需的科学方法。自2015年9月1日起，中共 该计划获得了 1700 万美元的年度拨款总额，其中 730 万美元来自 NCI，640 万美元来自其他同行。 审查了资金。中共党员共投稿癌症相关稿件570篇，其中37%为党内内部稿件 程序化，22% 是程序间化。实现党的科学奋斗目标的能力 该计划植根于该计划在 CPC 成员之间以及与其他 UACC 计划之间的强有力的互动 以及其国内和国际合作。