Expansion of normative database for wide-band acoustic immittance measures to include children and abnormal ears and analyses of data across studies and underlying assumptions

扩大宽带声导抗测量的规范数据库，将儿童和异常耳朵纳入其中，并对跨研究和基本假设的数据进行分析

• 批准号: 9812310
• 负责人: SUSAN E VOSS
• 金额: $ 38.72万
• 依托单位: SMITH COLLEGE
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-06-05 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9812310
• 关键词: Acoustics; Adult; Affect; Age; Area; Arts; Auditory; Auditory system; Child; Clinical; Collection; Communities; Complex; Conductive hearing loss; Data; Data Analyses; Databases; Detection; Development; Devices; Diagnostic; Disease; Ear; Education; Engineering; Equipment; External auditory canal; FDA approved; Family; Future; Goals; Grant; Guidelines; Hearing; Individual; Industry; Infant; Intracranial Pressure; Laboratories; Lead; Learning; Liquid substance; Location; Measurement; Measures; Medical; Methods; Monitor; Newborn Infant; Pathologic; Pathology; Phase; Play; Published Database; Publishing; Reporting; Research; Role; Scanning; Science; Students; System; Testing; Tympanometry; Ultrasonography; Variant; Woman; Work; age group; base; clinical application; college; data access; design and construction; electric impedance; experience; hearing impairment; instrument; middle ear; normal hearing; sex; statistics; tool; undergraduate education; undergraduate student; web site

PROJECT SUMMARY / ABSTRACT This work aims to develop wideband acoustic immittance (WAI) measures as a noninvasive auditory diagnostic tool, where WAI refers to the collection of measurements that include absorbance, power reflectance, impedance, and related quantities. Potential use of these measures includes (1) detection of fluid in newborn and young infant ears where tympanometry is less successful, (2) identification of the cause of a conductive hearing loss (e.g., fluid, disarticulated ossicle, fixed ossicle), and (3) monitoring changes in middle-ear stiffness that result from intracranial pressure changes. The proposed work ex- tends the world's only online WAI database and corresponding website, which was developed during the first cycle of this grant, from WAI measurements on normative adult ears to also include ears with specific pathologies and ears of babies and children. The proposed work also includes (1) laboratory- based acoustical measurements and CT ear-canal scans to understand why the two FDA-approved WAI measurement systems have systematic differences in their measurements and (2) utilizing the database to perform data analyses across studies to compare WAI measures on both normal ears and ears with specific pathologies in order to identify WAI features that best differentiate between normal ears and ears with specific pathologies. A second emphasis of the proposed work is the research-based education of undergraduate students at Smith College, an all-women's liberal arts college. Undergraduate engi- neering students will be actively involved in all areas of the proposed work, with the goal of encouraging them to continuing their education at the graduate level.

项目摘要 /摘要 这项工作旨在开发宽带声学止痛（WAI）措施作为无创的听觉 诊断工具，WAI是指包括吸光度，功率在内的测量收集 反射，阻抗和相关数量。这些措施的潜在使用包括（1）检测 新生儿和婴儿耳朵中的流体，鼓膜法不太成功，（2）鉴定 导电性听力损失的原因（例如，流体，脱节的骨，固定的骨），（3）监测 颅内压变化导致的中耳刚度的变化。拟议的工作前 趋向于世界上唯一的在线WAI数据库和相应的网站，该网站是在此期间开发的 这笔赠款的第一个周期，从正常成年耳朵的WAI测量值到还包括耳朵 婴儿和儿童的特定病理和耳朵。拟议的工作还包括（1）实验室 - 基于声学的测量和CT耳式扫描，以了解为什么两个FDA批准的WAI 测量系统在其测量方面存在系统差异，（2）使用数据库 跨研究进行数据分析，以将正常耳朵和耳朵的WAI度量与 特定的病理是为了确定最能区分正常耳朵和的WAI特征 耳朵具有特定的病理。拟议工作的第二个重点是基于研究的教育 史密斯学院（Smith College）的本科生，一所女性文科学院。本科 Neuring学生将积极参与拟议工作的所有领域，目的是鼓励 他们继续在研究生层面继续接受教育。

项目成果

Measurements of ear-canal geometry from high-resolution CT scans of human adult ears.

通过成人耳朵的高分辨率 CT 扫描测量耳道几何形状。

• DOI: 10.1016/j.heares.2023.108782
• 发表时间: 2023
• 期刊: Hearing research
• 影响因子: 2.8
• 作者: Balouch,AudenP;Bekhazi,Karen;Durkee,HannahE;Farrar,RebeccaM;Sok,Mealaktey;Keefe,DouglasH;Remenschneider,AaronK;Horton,NicholasJ;Voss,SusanE
• 通讯作者: Voss,SusanE

Measurements of ear-canal cross-sectional areas from live human ears with implications for wideband acoustic immittance measurements.

活体人耳耳道横截面积的测量对宽带声导抗测量的影响。

• DOI: 10.1121/10.0002358
• 发表时间: 2020
• 期刊: The Journal of the Acoustical Society of America
• 作者: Voss,SusanE;Horton,NicholasJ;Fairbank,KatherineE;Xia,Lu;Tinglin,LaurenRK;Girardin,KathrynD
• 通讯作者: Girardin,KathrynD

Resource Review.

资源审查。

• DOI: 10.1097/aud.0000000000000790
• 发表时间: 2019
• 期刊: Ear and hearing
• 影响因子: 3.7
• 作者: Voss,SusanE

Absorbance Measurements From Normal-hearing Ears in the National Health and Nutrition Examination Survey, 2015-2016 and 2017-2020.

2015-2016 年和 2017-2020 年国家健康和营养检查调查中正常听力耳朵的吸光度测量。

• DOI: 10.1097/aud.0000000000001358
• 发表时间: 2023
• 期刊: Ear and hearing
• 影响因子: 3.7
• 作者: Sun,Jiayi;Horton,NicholasJ;Voss,SusanE
• 通讯作者: Voss,SusanE