Pediatric Endocrine Fellowship Training in Diabetes and Endocrine Research

糖尿病和内分泌研究的儿科内分泌奖学金培训

• 批准号: 9136119
• 负责人: LORRAINE E LEVITT KATZ
• 金额: $ 21.26万
• 依托单位: CHILDREN'S HOSP OF PHILADELPHIA
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-30 至 2019-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9136119
• 关键词: Childhood; Diabetes Mellitus; Endocrine; Fellowship; Research; Training

DESCRIPTION (provided by applicant):To address the severe shortage of academic pediatric endocrinologists, this Training Program will take advantage of the important new opportunities for advancing diabetes and endocrine research in children provided by such recent scientific advances as the Human Genome Project, islet transplantation and biomechanical and bio-engineered islets, and the NIH roadmap transformation of GCRC programs for patient- oriented research into Clinical Translational Science Awards. The Program will support Trainees during up to 2 years of research training at the fellowship level. The Training faculty includes 29 scientific mentors from the Children's Hospital and the Perelman School of Medicine at the University of Pennsylvania who have outstanding credentials and active funded research programs and well-established training records. These mentors will supervise Trainees in basic laboratory research and/or patient-oriented and translational research projects related to diabetes and endocrine disorders in children. Research opportunities will include several areas of basic research (Cell Function, Hormone Action, Mechanisms of Disease, Endocrine Physiology, and Transcriptional Regulation). Patient-oriented research opportunities will include Translational Research, Disease Mechanisms, Pathophysiology, Diabetes Complications, Genetics, Clinical Trials, Metabolic Syndrome, Nutrition, and Epidemiology. The Program includes multiple interactions for Trainees with basic and clinical research and training in all aspects of research, including biostatistics, bioethics, molecular biology, etc. The Program is strongly supported by access to a superb range of institutional resources at Children's Hospital and University of Pennsylvania, including the CTSA and the University of Pennsylvania DERC. The request is made to support 3 fellow slots and 2 student slots in this Program each year. The long-term goal of this T32 Training Program renewal is to develop a new generation of pediatric endocrinologists who will be equipped to carry out innovative and scientifically rigorous patient- oriented and laboratory-based research in diabetes and endocrine disorders of children.

DESCRIPTION (provided by applicant):To address the severe shortage of academic pediatric endocrinologists, this Training Program will take advantage of the important new opportunities for advancing diabetes and endocrine research in children provided by such recent scientific advances as the Human Genome Project, islet transplantation and biomechanical and bio-engineered islets, and the NIH roadmap transformation of GCRC programs for patient- oriented research into Clinical Translational Science Awards.该计划将在奖学金水平的最多2年的研究培训期间为受训者提供支持。培训学院包括来自儿童医院的29名科学导师和宾夕法尼亚大学的佩雷尔曼医学院，他们拥有出色的证书和活跃的资助研究计划和良好的培训记录。这些导师将监督与儿童糖尿病和内分泌疾病有关的基础实验室研究和/或面向患者和转化研究项目的受训者。研究机会将包括基础研究的几个领域（细胞功能，激素作用，疾病机制，内分泌生理学和转录调节）。面向患者的研究机会将包括转化研究，疾病机制，病理生理学，糖尿病并发症，遗传学，临床试验，代谢综合征，营养和流行病学。该计划包括针对研究人员的多次互动，包括研究的各个方面，包括生物伦理学，生物伦理学，分子生物学等。该计划得到了在儿童医院和宾夕法尼亚大学（包括CTSA和宾夕法尼亚大学）中获得一系列机构资源的强烈支持。提出要求在该计划中支持3个同胞和2个学生老虎机。这项T32培训计划更新的长期目标是开发新一代的儿科内分泌学家，他们将有能力在儿童的糖尿病和内分泌疾病中进行创新且具有科学严格的以患者为导向的患者和基于实验室的研究。