Pediatric Endocrine Fellowship Training in Diabetes and Endocrine Research

糖尿病和内分泌研究的儿科内分泌奖学金培训

• 批准号: 8666899
• 负责人: LORRAINE E LEVITT KATZ
• 金额: $ 20.1万
• 依托单位: CHILDREN'S HOSP OF PHILADELPHIA
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-30 至 2019-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8666899
• 关键词: Childhood; Diabetes Mellitus; Endocrine; Fellowship; Research; Training

ABSTRACT for T32 DESCRIPTION: To address the severe shortage of academic pediatric endocrinologists, this Training Program will take advantage of the important new opportunities for advancing diabetes and endocrine research in children provided by such recent scientific advances as the Human Genome Project, islet transplantation and biomechanical and bio-engineered islets, and the NIH roadmap transformation of GCRC programs for patient- oriented research into Clinical Translational Science Awards. The Program will support Trainees during up to 2 years of research training at the fellowship level. The Training faculty includes 29 scientific mentors from the Children's Hospital and the P e r e l m a n S c h o o l o f M e d i c i n e a t University of Pennsylvania who have outstanding credentials and active funded research programs and well-established training records. These mentors will supervise Trainees in basic laboratory research and/or patient-oriented and translational research projects related to diabetes and endocrine disorders in children. Research opportunities will include several areas of basic research (ss-Cell Function, Hormone Action, Mechanisms of Disease, Endocrine Physiology, and Transcriptional Regulation). Patient-oriented research opportunities will include Translational Research, Disease Mechanisms, Pathophysiology, Diabetes Complications, Genetics, Clinical Trials, Metabolic Syndrome, Nutrition, and Epidemiology. The Program includes multiple interactions for Trainees with basic and clinical research and training in all aspects of research, including biostatistics, bioethics, molecular biology, etc. The Program is strongly supported by access to a superb range of institutional resources at Children's Hospital and University of Pennsylvania, including the CTSA and the University of Pennsylvania DERC. The request is made to support 3 fellow slots and 2 student slots in this Program each year. The long-term goal of this T32 Training Program renewal is to develop a new generation of pediatric endocrinologists who will be equipped to carry out innovative and scientifically rigorous patient- oriented and laboratory-based research in diabetes and endocrine disorders of children.

T32的摘要 描述：为了解决学术儿科内分泌学家严重短缺，该培训计划 将利用重要的新机会来推进糖尿病和内分泌研究 由人类基因组项目，胰岛移植和 生物力学和生物工程胰岛，以及用于患者的GCRC计划的NIH路线图转换 - 针对临床转化科学奖的研究。该计划将在最多支持学员 在奖学金水平上进行了2年的研究培训。培训教师包括来自的29位科学导师 儿童医院和宾夕法尼亚州大学 出色的证书和积极资助的研究计划以及良好的培训记录。这些 导师将监督基础实验室研究和/或面向患者和翻译的受训者 研究项目与儿童的糖尿病和内分泌疾病有关。研究机会将 包括基础研究的几个领域（SS细胞功能，激素作用，疾病机制， 内分泌生理和转录调节）。面向患者的研究机会将包括 翻译研究，疾病机制，病理生理学，糖尿病并发症，遗传学，临床 试验，代谢综合征，营养和流行病学。该程序包括多个交互 在包括生物统计学，包括生物统计学的各个方面的基础和临床研究和培训的学员 生物伦理学，分子生物学等。通过访问一流的范围，该程序得到了强有力的支持 儿童医院和宾夕法尼亚大学的机构资源，包括CTSA和 宾夕法尼亚大学DERC。提出了支持3个同胞和2个学生插槽的请求 每年计划。该T32培训计划的续签的长期目标是开发新一代 小儿内分泌学家将有能力进行创新且科学严格的患者 针对儿童的糖尿病和内分泌疾病的基于实验室的研究。