Pediatric Endocrine Fellowship Training in Diabetes and Endocrine Research

糖尿病和内分泌研究的儿科内分泌奖学金培训

• 批准号: 10177048
• 负责人: LORRAINE E LEVITT KATZ
• 金额: $ 9.48万
• 依托单位: CHILDREN'S HOSP OF PHILADELPHIA
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-30 至 2021-06-20
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10177048
• 关键词: Childhood; Diabetes Mellitus; Endocrine; Fellowship; Research; Training

ABSTRACT To address the severe shortage of academic pediatric endocrinologists, this Training Program will take advantage of the important new opportunities for advancing diabetes and endocrine research in children provided by such recent scientific advances as the Human Genome Project, islet transplantation and biomechanical and bio-engineered islets, and the NIH roadmap transformation of GCRC programs for patient- oriented research into Clinical Translational Science Awards. The Program will support Trainees during up to 2 years of research training at the fellowship level. The Training faculty includes 26 scientific mentors from the Children’s Hospital and the Perelman School of Medicine at University of Pennsylvania who have outstanding credentials and active funded research programs and well-established training records. These mentors will supervise Trainees in basic laboratory research and/or patient- oriented and translational research projects related to diabetes and endocrine disorders in children. Research opportunities will include several areas of basic research (ß-Cell Function, Hormone Action, Mechanisms of Disease, Endocrine Physiology, and Transcriptional Regulation). Patient-oriented research opportunities will include Translational Research, Disease Mechanisms, Pathophysiology, Diabetes Complications, Genetics, Clinical Trials, Metabolic Syndrome, Nutrition, and Epidemiology. The Program includes multiple interactions for Trainees with basic and clinical research and training in all aspects of research, including biostatistics, bioethics, molecular biology, etc. The Program is strongly supported by access to a superb range of institutional resources at Children’s Hospital and University of Pennsylvania, including the CTSA and the University of Pennsylvania DERC. The request is made to support 3 fellow slots in this Program each year. The long-term goal of this T32 Training Program renewal is to develop a new generation of pediatric endocrinologists who will be equipped to carry out innovative and scientifically rigorous patient- oriented and laboratory-based research in diabetes and endocrine disorders of children.

抽象的 为了解决严重的学术儿科内分泌学家的短缺，该培训计划将 利用重要的新机会来促进糖尿病和内分泌研究 在由人类基因组项目等最近的科学进步提供的儿童中 移植，生物力学和生物工程胰岛以及NIH路线图 转换用于患者研究的GCRC计划转化为临床翻译 科学奖。该计划将在最多2年的研究培训期间支持受训者 奖学金水平。培训教师包括来自儿童的26位科学导师 宾夕法尼亚大学的医院和佩雷尔曼医学院 出色的证书和积极资助的研究计划以及建立良好的培训 记录。这些导师将监督基础实验室研究和/或患者的受训者 - 与糖尿病和内分泌疾病有关的定向和翻译研究项目 孩子们。研究机会将包括基础研究的几个领域（ß细胞功能， 激素作用，疾病机制，内分泌生理和转录 规定）。面向患者的研究机会将包括转化研究，疾病 机制，病理生理学，糖尿病并发症，遗传学，临床试验，代谢 综合征，营养和流行病学。该计划包括针对受训者的多个互动 在研究的各个方面，包括生物统计学的基础和临床研究和培训， 生物伦理学，分子生物学等。该程序可以通过进入超级范围的强烈支持 儿童医院和宾夕法尼亚大学的机构资源，包括 CTSA和宾夕法尼亚大学DERC。提出了支持3个同胞的请求 每年在这个计划中。该T32培训计划的续签的长期目标是开发 新一代的儿科内分泌学家，等同于进行创新和 科学严格的糖尿病和内分泌方面的以患者为导向和基于实验室的研究 儿童疾病。