Transplant Infectious Diseases Interdisciplinary Research Training Grant (TIDIRTG

移植传染病跨学科研究培训补助金 (TIIRTG

• 批准号: 9283340
• 负责人: BARBARA D ALEXANDER
• 金额: $ 16.24万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-01 至 2018-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9283340
• 关键词: Communicable Diseases; Grant; Interdisciplinary Study; Research Training; Transplantation

DESCRIPTION (provided by applicant):Organ transplantation and cancer chemotherapy are life-saving interventions for an increasing number of patients. Despite important advances in surgical technique, immunosuppressive regimens, and the development of novel antimicrobial agents, these immunocompromised hosts remain at substantial risk for developing infections. Care of this complex patient population requires unique knowledge that differs from that of the general Infectious Diseases clinician. Accordingly, Transplant Infectious Diseases has emerged as a subspecialty within the field of Infectious Diseases (ID), and the American Society of Transplantation has developed a core curriculum for training specialists in Transplant ID. Duke University is uniquely poised to provide fellows with exceptional training in Transplant ID: Duke University Hospital is a major transplant and cancer care center with an active Transplant/Immunocompromised Host ID Service, ACGME-accredited Training Programs in ID and Medical Microbiology, and a highly qualified faculty committed to teaching fellows in the specialized area of Transplant ID including state-of-the-art methods of basic science and patient- oriented research. In fact, with minimal support over the past 10 years, the Duke ID Division has trained several successful young faculty who currently hold academic positions, specializing in Transplant ID care and research. The objective of this Training Program is to capitalize on the rich resources available at Duke in order to develop innovative ID physician-scientists trained in the care of immunocompromised hosts and the latest research methods. The combined research and clinical training program will occur after completion of at least one year of general clinical ID fellowship, which will include baseline Transplant ID experience. The Transplant ID core curriculum will include additional training in the clinical care of the transplant/immunocompromised host, training in laboratory medicine relevant to Transplant ID, and development of either basic or clinical research skills individualized to the trainee's expertise and career goals. Key areas for research training, as applicable to the Transplant/Immunocompromised host, will include: 1) laboratory medicine, 2) microbial epidemiology & pathogenesis, 3) host susceptibility & response to infection, and 4) medical management & treatment outcomes.

描述（由申请人提供）：器官移植和癌症化学疗法是越来越多的患者的挽救生命干预措施。尽管手术技术，免疫抑制方案和新型抗菌剂的发展取得了重要成就，这些免疫功能低下的宿主仍处于发展感染的巨大风险。对这个复杂的患者人群的照顾需要独特的知识，这些知识与普通感染疾病的临床医生不同。因此，移植传染病已成为传染病（ID）领域内的亚专业，美国移植学会为移植ID的培训专家开发了核心课程。杜克大学（Duke University）独特地准备在移植ID中为研究员提供出色的培训：杜克大学医院是一个主要的移植和癌症护理中心，拥有活跃的移植/免疫功能低下的宿主ID服务，ACGME经过的ID和医疗微生物学培训计划，以及高度合格的教师致力于在移植ID的专业领域教授研究员，包括基础科学和面向患者的研究的最先进方法。实际上，在过去的10年中，杜克ID部门的支持很少，培训了几位成功的年轻教师，他们目前担任学术职位，专门从事移植ID护理和研究。该培训计划的目的是利用杜克大学可用的丰富资源，以开发经过培训的ID医师 - 科学家，该医师接受了免疫功能低下的宿主和最新的研究方法的培训。联合研究和临床培训计划将在完成至少一年的一年临床ID奖学金后完成，其中包括基线移植ID经验。移植ID核心课程将包括对移植/免疫功能低下的宿主的临床护理，与移植ID相关的实验室医学培训以及发展基本或临床研究技能的培训。适用于移植/免疫功能低下的宿主的研究培训的关键领域将包括：1）实验室医学，2）微生物流行病学和发病机理，3）宿主易感性和对感染的反应，以及4）医疗管理和治疗结果。