mHealth and HIV self-testing for high-risk men in China

中国高危男性的移动健康和艾滋病毒自我检测

基本信息

批准号：
9264029
负责人：
DON OPERARIO
金额：
$ 20.16万
依托单位：
BROWN UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-08-01 至 2019-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9264029
关键词：
AIDS prevention Address Affect Antibodies Behavior Behavioral Car Phone Caring Centers for Disease Control and Prevention (U.S.)Characteristics China Chinese People Clinic Clinical Clinical Trials Cognitive Communities Continuity of Patient Care Country Cues Diagnostic tests Disclosure Effectiveness Excision Female Frequencies Goals Grant Guidelines HIV HIV Infections HIV diagnosis HIV risk HIV-1 Health Services Home environment Human immunodeficiency virus test Individual International Intervention Interview Libraries Light Link Motivation Outcome Persons Phase Policies Population Preventive Intervention Privacy Privatization Public Health Qualitative Research Recommendation Reporting Research Research Proposals Risk Risk Behaviors Risk Reduction Sampling Science Self-Administered Services Stigmatization Subgroup Techniques Technology Test Result Testing Time Unsafe Sex Vendor base behavior change behavior test dosage evidence based guidelines high risk men high risk population implementation science improved innovation intervention program mHealth male men who have sex with men mobile application mobile computing motivated behavior prevention service public health relevance same sex behavior scale up sex risk social stigma transmission process uptake

项目摘要

DESCRIPTION (provided by applicant): In this R34 application (PAR-14-179: Clinical Trial Planning Grant for Interventions and Services to Improve Treatment and Prevention of HIV/AIDS), we propose to develop and pilot test an intervention to improve the science of HIV self-testing (HST) as a public health strategy to increase HIV testing among populations with low testing rates. HST offers a compelling strategy for achieving higher levels of HIV testing, due to the reduced barriers associated with seeking traditional forms of clinic-based HIV testing. However, HST scale-up alone is insufficient as a public health strategy: individuals who receive an HST negative result require motivation to engage in repeat testing and encouragement to reduce their risk behaviors. Thus, we propose a combination strategy that incorporates HST with mobile application- ("app"-) based HIV risk reduction and behavior change motivation messages. The proposal research will take place in China, where our prior research has demonstrated low rates of testing, high behavioral risk, and barriers to clinical HIV prevention services among men who have sex with men (MSM). The research will leverage the broad general access to mobile phone and app-based electronic messaging technology in the Chinese population to develop a test a combined HST plus mHealth app-based messaging strategy for MSM. We will use a three-phase research approach to address our specific aims. First, we will conduct formative qualitative research to understand the facilitators and barriers to HIV self-testing (HST) among MSM in China. Second, based on qualitative findings, we will develop a library of brief messages to motivate risk reduction and behavior change, and we will use cognitive interviewing techniques and an open pilot to refine and finalize the app-based messaging content and implementation strategy. Third, we will pilot test the combination of HST plus mobile app-based risk reduction messaging compared to HST alone in a sample of high-risk MSM, with respect to repeat HST and changes in sexual risk behaviors in the next 6 months. The proposed study is innovative because it is the first known attempt to develop a combination approach to HST that leverages advances in mobile technology as a platform for repeat testing and motivating behavior change. We will use findings to support a subsequent application to test the effectiveness of the combined HST plus app-based messaging intervention on sexual risk behavior and HIV retesting.

说明（由申请人提供）：在此 R34 申请中（PAR-14-179：改善艾滋病毒/艾滋病治疗和预防的干预措施和服务的临床试验规划补助金），我们建议开发并试点测试一种干预措施，以提高科学性HIV 自我检测 (HST) 作为一项公共卫生策略，旨在提高检测率低的人群中的 HIV 检测水平，因为减少了寻求传统形式的诊所相关的障碍，HST 为实现更高水平的 HIV 检测提供了令人信服的策略。基于艾滋病毒然而，仅扩大 HST 作为一项公共卫生策略是不够的：收到 HST 阴性结果的个人需要动力进行重复测试和鼓励，以减少他们的危险行为。因此，我们提出了一种将 HST 与 HST 相结合的组合策略。该提案研究将在中国进行，因为我们之前的研究发现，中国的检测率低、行为风险高，并且临床艾滋病预防服务存在障碍。男男性行为者 (MSM)。将利用中国人群广泛使用的手机和基于应用程序的电子信息技术，为 MSM 开发一项 HST 与基于移动医疗应用程序的综合信息策略的测试。我们将采用三阶段研究方法来解决我们的具体问题。首先，我们将开展形成性定性研究，以了解中国男男性行为者艾滋病毒自我检测（HST）的促进因素和障碍。其次，我们将根据定性研究结果，开发一个简短信息库，以激励降低风险和行为。改变，我们将使用认知第三，我们将在高风险 MSM 样本中对 HST 与基于移动应用程序的风险降低消息传递的组合进行试点测试，并与单独的 HST 进行比较。关于未来 6 个月内重复 HST 和性风险行为的变化，这项研究具有创新性，因为这是首次已知的尝试开发 HST 组合方法，利用移动技术的进步作为重复测试和性风险行为的平台。我们将使用激励行为改变。研究结果支持随后的应用程序，以测试 HST 与基于应用程序的消息传递干预相结合对性危险行为和 HIV 重新检测的有效性。