Knee Biofeedback Rehabilitation Interface for Game-based Home Therapy (KneeBRIGHT)

用于基于游戏的家庭治疗的膝关节生物反馈康复接口 (KneeBRIGHT)

• 批准号: 9794639
• 负责人: Eileen T. Krepkovich
• 金额: $ 83.27万
• 依托单位: BARRON ASSOCIATES, INC.
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-30 至 2022-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9794639
• 关键词: Activities of Daily Living; Address; Adherence; Architecture; Area; Award; Biofeedback; Certification; Clinic; Clinical Trials; Computer software; Degenerative polyarthritis; Development; Disease; Electrodes; Electromyography; Evidence based practice; Exercise; Exercise Therapy; Exhibits; Feasibility Studies; Feedback; Goals; Health Services Accessibility; Home environment; Insurance; Interview; Knee; Knee Osteoarthritis; Laboratories; Measures; Modeling; Motivation; Muscle; Outcome; Pain; Patient Monitoring; Patients; Performance; Phase; Physical Function; Production; Protocols documentation; Provider; Public Health; Recovery of Function; Rehabilitation therapy; Resistance; Risk; Safety; Small Business Innovation Research Grant; Symptoms; System; Technology; Teletherapy; Testing; Time; Torque; Training; Travel; United States; Universities; Validation; Video Games; Virginia; Wireless Technology; arthropathies; base; compliance behavior; cost; dashboard; design; disability; efficacy testing; evidence base; exercise regimen; exercise rehabilitation; experience; functional improvement; functional outcomes; functional status; improved; innovation; muscle strength; pain reduction; pain symptom; patient engagement; programs; prototype; quadriceps muscle; sensor; strength training; success; tool; usability

PROJECT SUMMARY/ABSTRACT Significance: The Knee Biofeedback Rehabilitation Interface for Game-based Home Therapy (“KneeBRIGHT”) system combines electromyography (EMG) biofeedback with video game therapy (VGT) to provide knee osteoarthritis (OA) patients with an engaging, effective tool for conducting rehabilitation exercises at home. KneeBRIGHT aims to motivate patients with knee OA to conduct regular muscle strengthening exercise through an engaging, EMG-driven video game therapy. The system combines wireless EMG electrodes that are convenient for patients to use in a home setting with software that provides automated guidance through evidence-based, progressive exercise routines. Importantly, these exercises are presented to the patient in the form of fun and engaging games to promote a positive experience and encourage continued adherence. Problem to be Addressed: OA is the leading cause of disability in the United States. Rehabilitation through quadriceps strengthening is a well-established treatment for patients with OA of the knee, but patient adherence to exercise routines is low due to lack of guidance regarding optimal protocols and lack of engagement during the repetitive routines that patients find tedious and boring. Long-Term Goal: Improve knee OA outcomes through effective and motivating rehabilitation exercises. Phase I Results: During the Phase I effort, a prototype KneeBRIGHT system was developed and verified in a laboratory setting. The feasibility testing with 19 knee OA patients demonstrated statistically significant increases in muscle activation, engagement levels, and duration of voluntary exercise during the KneeBRIGHT exercises when compared with exercises conducted with a conventional EMG biofeedback system. Phase II Hypotheses: The Phase II program will test the hypotheses that patients performing exercise routines using KneeBRIGHT will: (1) achieve superior muscle strength gain compared to a conventional EMG biofeedback protocol; and (2) exhibit increased adherence compared to the conventional system. Phase II Summary: Barron Associates (award-winning innovators in video game therapy) has partnered with the University of Virginia for this SBIR Phase II program to demonstrate efficacy and user acceptance of the KneeBRIGHT system. The specific objectives of the Phase II program are to: (1) develop the Phase II commercial KneeBRIGHT EMG modules; (2) develop the Phase II commercial KneeBRIGHT game software with adaptive exercise protocols and expanded game activities; (3) develop a provider dashboard to enable clinicians to monitor patient performance remotely; and (4) perform efficacy testing of muscle strength, functional improvement (via Knee Osteoarthritis Outcome Score), and adherence (when compared to a conventional system) with knee OA patients in a 12-week clinical trial. Impact: The system will have a significant overall impact on public health by increasing patient adherence to home exercise and thereby reducing pain symptoms and restoring physical function to knee OA patients.

项目概要/摘要 意义：基于游戏的家庭治疗的膝关节生物反馈康复接口（“KneeBRIGHT”） 系统将肌电图 (EMG) 生物反馈与视频游戏疗法 (VGT) 相结合，为膝关节提供治疗 为骨关节炎 (OA) 患者提供一种在家进行康复锻炼的有效工具。 KneeBRIGHT旨在激励膝关节骨关节炎患者定期进行肌肉强化锻炼 通过一种引人入胜的、肌电图驱动的视频游戏疗法，该系统结合了无线肌电图电极， 方便患者在家庭环境中使用软件，通过以下方式提供自动指导 重要的是，这些练习是在临床实践中呈现给患者的。 有趣且引人入胜的游戏形式，以促进积极的体验并鼓励持续坚持。 要解决的问题：OA 是美国康复的主要原因。 股四头肌强化对于膝关节 OA 患者来说是一种行之有效的治疗方法，但患者 由于缺乏最佳方案的指导以及缺乏锻炼习惯，锻炼习惯的遵守率很低。 参与患者认为乏味和无聊的重复例行程序。 长期目标：通过有效且激励性的康复锻炼改善膝关节 OA 的结果。 第一阶段结果：在第一阶段工作中，开发了 KneeBRIGHT 系统原型并在 实验室环境对 19 名膝关节 OA 患者进行的可行性测试表明具有统计学意义。 KneeBRIGHT 期间肌肉激活、参与水平和自愿锻炼持续时间增加 与使用传统肌电图生物反馈系统进行的练习相比。 第二阶段假设：第二阶段计划将测试患者进行日常锻炼的假设 使用 KneeBRIGHT 将：(1) 与传统 EMG 相比，实现卓越的肌肉力量增益 生物反馈方案；(2) 与传统系统相比，表现出更高的依从性。 第二阶段总结：Barron Associates（视频游戏治疗领域屡获殊荣的创新者）与 弗吉尼亚大学参与此 SBIR 第二阶段计划，以证明其功效和用户接受度 KneeBRIGHT系统第二阶段计划的具体目标是：（1）开发第二阶段。 商用KneeBRIGHT肌电图模块；（2）开发第二期商用KneeBRIGHT游戏软件； (3) 开发一个提供商仪表板以启用 (4) 进行肌力功效测试， 功能改善（通过膝骨关节炎结果评分）和依从性（与 传统系统）对膝骨关节炎患者进行了为期 12 周的临床试验。 影响：该系统将通过提高患者的依从性，对公共健康产生重大的整体影响。 家庭锻炼，从而减轻膝关节骨关节炎患者的疼痛症状并恢复身体功能。