Regulating axon guidance through local translation at adhesions

通过粘连处的局部翻译调节轴突引导

• 批准号: 10841832
• 负责人: Kristy Welshhans
• 金额: $ 4.34万
• 依托单位: UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-01 至 2028-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10841832
• 关键词: Academia; Adhesions; Award; Biology; Cellular Neurobiology; Development Plans; Disease; Doctor of Philosophy; Faculty; Funding; Goals; Health; Jordan; Laboratories; Mentors; Molecular; Molecular Neurobiology; Neurosciences; Parents; Publications; Publishing; Qualifying; Research; Research Project Summaries; Science; Training; Translations; United States National Institutes of Health; Universities; Work; axon guidance; career; career development; experience; member; nerve injury; neuroinflammation; pre-doctoral; professor; programs; undergraduate student

PROJECT SUMMARY This Research Supplement to Promote Diversity in Health-Related Research (PA-21-071) is to support Jordan Headen to pursue predoctoral training in my laboratory. This proposal is a supplement to my currently funded NIH R01 award (NS125146). In the proposal, we provide a summary of the original (parent) R01, a research plan for the candidate, a career development plan for the candidate, and the PI’s qualifications to mentor the candidate. Ms. Headen completed her Bachelor of Science degree in Biology at Ball State University. During her undergraduate, she worked in the Neuroscience laboratory of Dr. Ashley Kalinski, examining molecular mechanisms contributing to neuroinflammation after nerve injury. As an undergraduate, Ms. Headen published one co-authored publication. Ms. Headen’s long-term career plans are to become an independent faculty member in academia with a research focus on neuroscience. This supplement will provide Ms. Headen with extensive research experience in molecular and cellular neurobiology, focusing on mechanisms underlying local translation during axon guidance. Furthermore, this supplement will provide Ms. Headen with focused career development training. Overall, this supplement will provide the training needed to submit a strong F31 application at the beginning of her third year in the Ph.D. program and help her achieve her goal of becoming a neuroscience professor in academia.

项目概要 本研究增刊旨在促进健康相关研究的多样性 (PA-21-071) 支持乔丹·海登（Jordan Headen）在我的实验室进行博士前培训。 对我目前资助的 NIH R01 奖 (NS125146) 的补充 在提案中，我们提供了一个 原（母）R01摘要、候选人的研究计划、职业发展 候选人的计划，以及 PI 指导候选人的资格。 在此期间，她在鲍尔州立大学获得了生物学学士学位。 本科期间，她在 Ashley Kalinski 博士的神经科学实验室工作，研究 神经损伤后神经炎症的分子机制。 本科期间，海登女士出版了一份与人合着的长期出版物。 职业计划是成为学术界的一名独立教员，以研究为重点 该补充品将为 Headen 女士提供丰富的研究经验。 分子和细胞神经生物学，重点研究局部翻译的机制 此外，该补充品将为 Headen 女士提供重点关注。 总体而言，本补充材料将提供提交所需的培训。 在她攻读博士学位的第三年开始时，她获得了强有力的 F31 申请，并帮助她。 实现她成为学术界神经科学教授的目标。