Tagging of Histopathology Specimens with Light-Activated RFID p-Chips

使用光激活 RFID p 芯片标记组织病理学样本

• 批准号: 8393365
• 负责人: WLODEK MANDECKI
• 金额: $ 56.08万
• 依托单位: PHARMASEQ, INC.
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-02-01 至 2014-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8393365
• 关键词: Adherence; Adhesives; Adoption; Amplifiers; Appearance; Area; Benchmarking; Charge; Chemicals; Clinical Trials; Communication; Computer software; Computers; Contractor; Custom; Databases; Diagnostic; Docking; Electronics; Epoxy Compounds; Evaluation; Feedback; Frequencies; Glass; Goals; Hand; Histopathology; Hospitals; Human Resources; Hybrids; Institution; Label; Laboratories; Lasers; Light; Link; Liquid substance; Maintenance; Manufacturer Name; Mechanics; Medical; Medical Research; Methods; Molds; Noise; Optics; Pathology; Performance; Play; Polypropylenes; Printing; Process; Protocols documentation; Provider; Readability; Reader; Reading; Research; Retrieval; Robot; Robotics; Role; Sampling; Scanning; Side; Signal Transduction; Silicon; Slide; Solutions; Solvents; Source; Specimen; System; Systems Development; Technology; Temperature; Testing; Texas; Tissue Sample; Tissue Stains; Tissues; Update; Validation; Wireless Technology; Work; anticancer research; base; chemical stability; cost; design; drug discovery; improved; instrument; knowledge base; lens; programs; prototype; validation studies; Adherence; Adhesives; Adoption; Amplifiers; Appearance; Area; Benchmarking; Charge; Chemicals; Clinical Trials; Communication; Computer software; Computers; Contractor; Custom; Databases; Diagnostic; Docking; Electronics; Epoxy Compounds; Evaluation; Feedback; Frequencies; Glass; Goals; Hand; Histopathology; Hospitals; Human Resources; Hybrids; Institution; Label; Laboratories; Lasers; Light; Link; Liquid substance; Maintenance; Manufacturer Name; Mechanics; Medical; Medical Research; Methods; Molds; Noise; Optics; Pathology; Performance; Play; Polypropylenes; Printing; Process; Protocols documentation; Provider; Readability; Reader; Reading; Research; Retrieval; Robot; Robotics; Role; Sampling; Scanning; Side; Signal Transduction; Silicon; Slide; Solutions; Solvents; Source; Specimen; System; Systems Development; Technology; Temperature; Testing; Texas; Tissue Sample; Tissue Stains; Tissues; Update; Validation; Wireless Technology; Work; anticancer research; base; chemical stability; cost; design; drug discovery; improved; instrument; knowledge base; lens; programs; prototype; validation studies

DESCRIPTION (provided by applicant): The purpose of the present project is to develop and validate the use of ultra-small RFID chips to tag and track tissue cassettes and glass slides that are used in histopathology laboratories. The system is based on the PharmaSeq laser light-activated microtransponder, also known as "p-Chip". The chip's major advantages are its small size (500 ¿m x 500 ¿m x 100 ¿m), unitary design, inertness, ease of use and very low cost. The system consists of the p-Chip-tagged glass slides and tissue cassettes, a stationary reader, a portable reader for trays with slides, and associated software that allows integration with common database software. The main goals of the project are to: 1) develop semi-automated methods of attaching p-Chips to slides and cassettes, 2) build advanced prototypes of the ID reader (wand) and improve key features, such as the form factors for reading each type of container, 3) improve the design of the p-Chip to increase the read range and refine methods of their post-fabrication processing, and 4) conduct extensive pilot test studies with outside collaborators to validate the system. The ID readers will have a modified optical system and will feature wireless communication between the reader and a workstation or central computer. The adoption of the system will improve reliability for tagging and tracking tissue samples. PUBLIC HEALTH RELEVANCE: Pathology specimens play an important role in research and medical practice, and are analyzed and stored in increasingly large quantities. The new PharmaSeq RFID tracking system has the potential to greatly improving the reliability of maintaining the providence for large numbers of samples using a new type of electronic identification system. Medical studies, including cancer research, clinical investigations, in vitr diagnostics and drug discovery fields will all benefit.

描述（由适用提供）：本项目的目的是开发和验证使用组织病理学实验室中使用的超小型RFID芯片在标记和跟踪组织盒和载玻片。该系统基于Pharmaseq Laser光激活的微转带，也称为“ P-Chip”。芯片的主要优点是其尺寸很小（500？m x 500€m x 100€），单一设计，惰性，易用性和非常低的成本。该系统由P-Chip标记的载玻片和纸巾，固定读取器，带幻灯片的便携式读取器以及允许与常见数据库软件集成的相关软件。该项目的主要目标是：1）开发将P-CHIP连接到幻灯片和盒式磁带的半自动化方法，2）构建ID读取器（WAND）的先进原型（WAND）并改善关键特征，例如阅读每种容器的形式，3）与P-chip的读取范围和进一步的范围和精炼方法进行了研究，并在其后进行了研究，并进行了处理的方法，并进行了处理，并进行了fipine fieltors for-fipers files，并4.验证系统。 ID读取器将具有修改后的光学系统，并将具有读取器与工作站或中央计算机之间的无线通信。该系统的采用将提高标记和跟踪组织样品的可靠性。 公共卫生相关性：病理标本在研究和医学实践中起着重要作用，并被越来越多地分析和存储。新的Pharmaseq RFID跟踪系统具有极大的提高，可以使用新型的电子识别系统来维持大量样品的规定。医学研究，包括癌症研究，临床研究，VITR诊断和药物发现领域都将受益。