Administrative Core

行政核心

基本信息

批准号：
10704388
负责人：
JUDITH A JAMES
金额：
$ 17.05万
依托单位：
OKLAHOMA MEDICAL RESEARCH FOUNDATION
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-09-07 至 2028-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10704388
关键词：
Acceleration Adult Advisory Committees Advocate Aliquot Autoantibodies Autoimmune Autoimmunity Award Blood Vessels Cardiology Certification Childhood Clinical Clinical Data Clinical Investigator Clinical Research Clinical Trials Coagulation Process Code Collaborations Collection Communication Communities Connective Tissue Diseases Data Databases Degenerative polyarthritis Dermatology Development Discipline Disease Distant Educational workshop Endocrinology Ensure Epidemiologist Epidemiology Etiology Evaluation Exposure to Fostering Funding Future Gene Expression Profiling Genetic Genotype Geriatrics Goals Grant Hematology House Staffs Human Human Resources Hypersensitivity Immune Immunologist Immunology Individual Inflammation Institution Investigation Investments Leadership Lupus Manuscripts Mediator Medicine Mentors Mission Molecular National Institute of Arthritis, and Musculoskeletal, and Skin Diseases Oklahoma Oncology Participant Pathogenesis Patients Phenotype Precision therapeutics Prevention Program Development PubMed Publications Qualitative Evaluations Quantitative Evaluations Research Research Personnel Research Project Grants Resources Rheumatism Rheumatology Sampling Scholars Program Science Series Services Sjogren&apos s Syndrome Structure Students Suggestion Systemic Lupus Erythematosus Technology Testing Therapeutic Trials Underrepresented Populations Undifferentiated United States National Institutes of Health Writing biobank career career development clinical care clinical phenotype effectiveness evaluation forging improved interdisciplinary approach interest meetings member molecular pathology multidisciplinary novel outreach patient subsets preclinical study programs success symposium tribal community undergraduate student user-friendly web-enabled

项目摘要

The Oklahoma Rheumatic Disease Research Cores Center (ORDRCC) facilitates, supports, and grows collaborative rheumatic disease research through fostering junior rheumatic disease investigator career development, forging national collaborations, making available cutting-edge technologies, and providing well- phenotyped clinical data and biospecimens to understand the pathogenesis, prediction, prevention, and precision treatment of rheumatic diseases. These goals are being met and have resulted in the successful launch of at least 33 new rheumatic disease investigator careers (local and distant), new or renewed collaborative, multi-investigator NIH rheumatic disease research grants, increasing collaborations, novel NIH- funded and investigator-initiated clinical trials with partnered mechanistic studies, and enhanced diversity in rheumatic disease research and researchers. The ORDRCC includes individuals from numerous scientific and clinical disciplines, spanning 26 current center investigators, 22 junior center investigators (12 local, 10 distant) and 12 nominated Scholars. The Administrative Core serves as the ORDRCC centralized governing resource and a liaison between the ORDRCC leadership, the Research Cores, all Center Investigators, and the Advisory Committee. The main purpose of Admin Core is to develop new rheumatic disease investigators through local and distant Junior Center Investigator and Scholars programs which expand use of our patient collections and clinical data, as well as access to advanced technologies. We propose a new structured pipeline program to provide early exposure to rheumatic disease patients and investigation to trainees spanning from undergraduates to housestaff. We will also augment a multi-faceted Enrichment Program with weekly seminars and an annual all-day symposium with new web-enabled workshops for professional development, a new Scientific Writing Success Center, and an expanded formalized mentor-development program. The Administrative Core also serves as the primary communication hub for the ORDRCC. Based upon input from our patient advisors, we propose to expand communication with our patients and their advocates, as well as broaden communication to our new external partners, outside JCIs/Scholars and the broader scientific community. The ORDRCC will expand Core and Collection use and outreach through collaborations with other Center awards. Finally, the Administrative Core will provide oversight, management, and prioritization of resources, ensure regulatory compliance, and grant management oversight and serve as the nidus for interactions with the Advisory Committee which is inclusive of Internal and External members to ensure suggestions are vetted and implemented. This Core will also provide the overall Leadership and oversight for the Center. The ORDRCC will use annual evaluations and assessments, both qualitative and quantitative, to ensure the Center is meeting goals and to help prioritize resources, assess effectiveness, and refine the program as necessary to ensure the needs of our patients, participants and investigators are met.

俄克拉荷马州风湿病研究核心中心 (ORDRCC) 促进、支持和发展通过培养初级风湿病研究者职业来开展协作风湿病研究发展，建立国家合作，提供尖端技术，并提供良好的表型临床数据和生物样本，以了解发病机制、预测、预防和风湿性疾病的精准治疗。这些目标正在实现并取得成功启动至少 33 个新的风湿病研究者职业（本地和远程），无论是新的还是更新的合作、多研究者 NIH 风湿病研究资助、增加合作、新颖的 NIH- 资助和研究者发起的临床试验以及合作机制研究，并增强了多样性风湿病研究和研究人员。 ORDRCC 包括来自众多科学界和临床学科，涵盖 26 名现任中心研究人员、22 名初级中心研究人员（12 名本地研究人员、10 名远程研究人员）和 12 名提名学者。管理核心作为 ORDRCC 集中管理资源 ORDRCC 领导层、研究核心、所有中心研究人员和咨询委员会。 Admin Core的主要目的是培养新的风湿病研究者通过当地和远程初级中心调查员和学者计划扩大了我们患者的使用收集和临床数据，以及先进技术的获取。我们提出了一种新的结构为风湿病患者提供早期接触并对受训人员进行调查的管道计划从本科生到住宿人员。我们还将加强多方面的丰富计划每周研讨会和年度全天研讨会，为专业人士提供新的网络研讨会发展，一个新的科学写作成功中心，以及扩大的正规导师发展程序。管理核心还充当 ORDRCC 的主要通信中心。基于根据患者顾问的意见，我们建议扩大与患者及其患者的沟通倡导者，以及扩大与我们新的外部合作伙伴、JCI/学者和外部合作伙伴的沟通更广泛的科学界。 ORDRCC 将通过以下方式扩大核心和集合的使用和外展：与其他中心奖项的合作。最后，行政核心将提供监督、管理、和资源的优先顺序，确保合规性，并授予管理层监督权并充当与咨询委员会互动的核心，该委员会包括内部和外部成员确保建议得到审查和实施。该核心还将提供整体领导力和对中心的监督。 ORDRCC 将使用年度评价和评估，包括定性和评估定量，以确保中心实现目标并帮助确定资源的优先顺序、评估有效性和根据需要完善计划，以确保满足患者、参与者和研究人员的需求。