Nanotechnology in Biosensors and Bioengineering

生物传感器和生物工程中的纳米技术

• 批准号: 8137575
• 负责人: Yogesh K. Vohra
• 金额: $ 3.26万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8137575
• 关键词: Biomedical Engineering; Biosensor; Nanotechnology

DESCRIPTION (provided by applicant): Five basic science and engineering departments at UAB propose an interdisciplinary nanobiotechnology program at the interfaces of physics, chemistry, materials science, physiology, and biomedical engineering with a goal of reducing the time from discovery of a new nanotechnology tool or material to its application in medical devices, tissue engineering and biosensors. The trainees will be directly recruited in to the five participating graduate programs and will attend common interdisciplinary core courses, special-skills workshops, and a semester-long internship at the industrial and national lab sites. Areas for training include nanostructured biomaterials for dental, orthopedic, and cardiovascular implants, bioreactors for nanostructured scaffolds for tissue engineering, cell biology on nanoscale materials, and optical nanobiosensors. We request support for four predoctoral trainnes and one postdocdoctoral training for a five year period. The predoctoral training will be for a three year period while the postdoctoral training will be for a two year period. The participants in this program would have access to the state of the art nanotechnology tools and facilities to design materials and biosensors for disease detection, management, and prevention Our recruitment and retention goal is to achieve 20% minority participation in this training grant through partnerships with minority serving institutions. The graduate students advisory committee will consist of faculty from the participating departments and a clinical faculty member to advise student on the clinical relevance of nanotechnology research projects. This program will have an external advisory board with members representing nanotechnology constituents and will conduct a biannual external assessment. UAB administration is allocating resources to build, sustain and institutionalize this interdisciplinary training program through stipend supplements and administrative support to carry out a national recruitment to attract the best-qualified trainees to this emerging field of nanobiotechnology. Relevance: This training program would produce a highly skilled workforce that will apply nanotechnology to biomedical implants, biosensors for early diagnostics of diseases and regenrative medicine. Nanotechnology approaches will impove the longevity and function of biomedical implants and improve human health.

描述（由申请人提供）： 阿拉巴马大学的五个基础科学和工程系提出了一个跨学科的纳米生物技术项目，涉及物理、化学、材料科学、生理学和生物医学工程的交叉领域，目标是缩短从发现新的纳米技术工具或材料到其在医学中应用的时间设备、组织工程和生物传感器。学员将直接被招募到五个参与的研究生项目中，并将参加共同的跨学科核心课程、特殊技能研讨会以及在工业和国家实验室现场进行为期一个学期的实习。培训领域包括用于牙科、骨科和心血管植入物的纳米结构生物材料、用于组织工程的纳米结构支架的生物反应器、纳米级材料的细胞生物学以及光学纳米生物传感器。我们请求为四名博士前培训和一名博士后培训提供为期五年的支持。博士前培训为期三年，博士后培训为期两年。该计划的参与者将有机会使用最先进的纳米技术工具和设施来设计用于疾病检测、管理和预防的材料和生物传感器。我们的招募和保留目标是通过与少数民族服务机构。研究生咨询委员会将由参与院系的教职人员和一名临床教职人员组成，就纳米技术研究项目的临床相关性向学生提供建议。该计划将设立一个外部顾问委员会，其成员代表纳米技术成分，并将每两年进行一次外部评估。 UAB 管理部门正在分配资源，通过津贴补贴和行政支持来建立、维持和制度化这一跨学科培训计划，以进行全国招聘，以吸引最合格的学员进入这一新兴的纳米生物技术领域。相关性：该培训计划将培养一支高技能的劳动力队伍，将纳米技术应用于生物医学植入物、用于疾病早期诊断的生物传感器和再生医学。纳米技术方法将提高生物医学植入物的寿命和功能，并改善人类健康。