Drosophila Genomics Resource Center

果蝇基因组学资源中心

基本信息

批准号：
8055570
负责人：
JUSTEN R ANDREWS
金额：
$ 75.64万
依托单位：
TRUSTEES OF INDIANA UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2003
资助国家：
美国
起止时间：
2003-07-01 至 2013-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8055570
关键词：
Age Agriculture Alcohol dependence Alzheimer&apos s Disease Animal Genetics Archives Behavioral Biology Cell Line Cellular biology Cloning Vectors Communities DNA Development Developmental Biology Disease model Drosophila genome Drosophila genus Drug Addiction Ecology Educational workshop Electronic Mail Ensure Evolution Expressed Sequence Tags Funding Gene Expression Regulation Genes Genetic Genetic Models Genome Genomics Goals Guidelines Health Heart Diseases Homologous Gene Human Huntington Disease Indiana Industry Longevity Medical Modeling Molecular Names Natural Immunity Nerve Degeneration Neurobiology Online Systems Parkinson Disease Pathway interactions Philosophy Population Biology Protocols documentation Recording of previous events Regulation Research Resources Sequence Analysis Students Study models System Techniques Telephone Time Universities Writing fly functional genomics genome sequencing human disease improved interest mutant outreach pathogen posters symposium tool tumor progression

项目摘要

DESCRIPTION (provided by applicant): Drosophila is one of the outstanding models for studies of animal genetics, development, and regulation. As a genetic model, it has been characterized more fully than any other metazoan. At the same time, because of evolutionary conservation, Drosophila has turned out to be an important model for fundamental studies of medical, agricultural, and biotechnological interest. Thus, it appears that >75 percent of human disease genes have Drosophila homologs. The completed Drosophila genome sequence, ongoing EST projects, and the increasing application of high-throughput genomics techniques by fly workers are paving the way for a comprehensive functional genomics of Drosophila. To reach this goal, the community requires ready, economical access to quality-assured genomics materials. The Drosophila Genomics Resource Center (DGRC) provides the research community with access to genomics resources and facilitates their effective use. Specifically, the DGRC: 1. Ensures the research community broad access to genomics resources by acquiring, archiving, curating, and distributing genomics resources including, clones, vectors, cell lines, and microarrays. 2. Facilitates the effective use of genomics resources by the research community by providing web based descriptive documentation, protocols, and guidelines; email and telephone help desk; outreach at conferences; and workshops. 3. Improves the genomics resources and protocols available to the research community.

描述（由申请人提供）：果蝇是动物遗传学，发育和调节研究的杰出模型之一。作为遗传模型，它的表征比其他任何后生动物更全面。同时，由于进化保护，果蝇已成为医学，农业和生物技术兴趣基础研究的重要模型。因此，似乎75％的人类疾病基因具有果蝇同源物。完整的果蝇基因组序列，正在进行的EST项目和增加飞行工人对高通量基因组学技术的应用为果蝇的全面功能基因组学铺平了道路。为了实现这一目标，社区需要准备好，经济的访问质量得到的基因组学材料。果蝇基因组学资源中心（DGRC）为研究界提供了获得基因组学资源的机会，并促进了它们的有效使用。具体而言，DGRC：1。通过获取，归档，策划和分发基因组学资源，包括克隆，媒介，细胞系和微阵列，确保研究社区对基因组学资源的广泛访问。 2。通过提供基于Web的描述性文档，协议和准则，可以促进研究社区对基因组学资源的有效利用；电子邮件和电话服务台；会议的宣传；和讲习班。 3。改善研究界可用的基因组资源和协议。