High Performance PET/CT Scanner

高性能 PET/CT 扫描仪

• 批准号: 10630534
• 负责人: Ciprian Catana
• 金额: $ 200万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-05-01 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10630534
• 关键词: Accounting; Award; Boston; Cardiovascular Diseases; Clinical Research; Collaborations; Communities; Complement; Data; Fostering; Funding; Future; Generations; Grant; Image; Institution; Leadership; Lung diseases; Magnetic Resonance Imaging; Maintenance; Measurement; Oncology; Organ; PET/CT scan; Performance; Positron-Emission Tomography; Price; Radiation exposure; Radiology Specialty; Research; Research Personnel; Research Project Grants; Schedule; System; Time; Tracer; United States National Institutes of Health; Vision; biomedical imaging; detector; improved; instrument; instrumentation; meter; multidisciplinary; operation; programs; radiotracer; temporal measurement

Project Summary/Abstract This application seeks support from the ORIP High-End Instrumentation Grant program to purchase a high-performance PET/CT scanner to be used for basic/translational/clinical research at the MGH/HST Athinoula A. Martinos Center for Biomedical Imaging. The proposed instrument – Siemens Biograph Vision Quadra – has a 1-meter long axial field of view and uses the latest generation PET detectors with excellent time-of-flight performance. The one order of magnitude higher sensitivity of the Biograph Vision Quadra PET/CT would benefit existing and future projects by allowing investigators to: obtain higher quality PET images, reduce radiation exposure and/or imaging acquisition time, image longer time after radiotracer administration, perform simultaneous multi-organ dynamic acquisition, improve the PET data quantification, perform multi-tracer studies, increase the temporal resolution of the PET measurements, etc. These new opportunities will benefit the ongoing research projects of our multidisciplinary NIH-funded investigators from MGH and Greater Boston region. Furthermore, the substantially better PET performance combined with the high-performance CT will complement the capabilities of the conventional PET/MRI and MRI scanners installed at the Martinos Center and will foster opportunities for new projects and collaborations for projects ranging from cardiovascular and pulmonary diseases to oncological and non-oncological whole-body applications. The proposed purchase through this SIG is being supported by the MGH leadership, Radiology Department, and Martinos Center. This multi-level institutional support covers every aspect related to the upgrade and its future operations, including allocation of instrument space and assistance for installation, operational support in terms of system scheduling, accounting, and maintenance, and lastly but most significantly, a commitment of up to $7,500,000 to cover the gap between the NIH SIG award and the purchasing price for the upgrade, in addition to the committed fund of $150,000 from the MGH Executive Committee for Research towards the maintenance of the system. Following the installation, the Biograph Vision Quadra PET/CT will be managed by the Martinos Center as a shared core, and made available to the broader research community, both within MGH and the Greater Boston region.

项目概要/摘要 本申请寻求 ORIP 高端仪器补助计划的支持 购买高性能 PET/CT 扫描仪用于基础/转化/临床研究 MGH/HST Athinoula A. Martinos 生物医学成像中心 拟议的仪器。 – 西门子 Biograph Vision Quadra – 具有 1 米长的轴向视场，并采用最新的 新一代 PET 探测器，具有出色的飞行时间性能。 Biograph Vision Quadra PET/CT 的更高灵敏度将有利于现有和未来的项目 通过允许研究人员：获得更高质量的 PET 图像、减少辐射暴露和/或 成像采集时间，放射示踪剂施用后成像时间更长，同时进行 多器官动态采集，提高PET数据量化，执行多示踪剂 研究、提高 PET 测量的时间分辨率等。这些新机会 将使我们的多学科 NIH 资助的研究人员正在进行的研究项目受益 此外，MGH 和大波士顿地区的 PET 性能也显着提高。 与高性能 CT 相结合将补充传统 CT 的功能 马蒂诺斯中心安装了 PET/MRI 和 MRI 扫描仪，将为新的人员创造机会 项目和合作项目范围从心血管和肺部疾病到 肿瘤学和非肿瘤学全身应用。 SIG 得到了 MGH 领导层、放射科和 Martinos 中心的支持。 多层次的机构支持涵盖升级及未来的各个方面 操作，包括分配仪器空间和协助安装、操作 系统调度、会计和维护方面的支持，最后但也是最重要的 值得注意的是，承诺提供高达 7,500,000 美元的资金来弥补 NIH SIG 奖项与 升级的购买价格，加上 MGH 承诺的 150,000 美元资金 执行研究委员会致力于系统的维护。 安装后，Biograph Vision Quadra PET/CT 将由 Martinos 中心作为 共享核心，并提供给 MGH 和 MGH 内更广泛的研究界 大波士顿地区。