PROTEOMICS AND GENOMICS CORE FACILITY

蛋白质组学和基因组学核心设施

• 批准号: 7959183
• 负责人: ROBERT G HOLT
• 金额: $ 53.72万
• 依托单位: MEHARRY MEDICAL COLLEGE
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-01 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7959183
• 关键词: Acquired Immunodeficiency Syndrome; Area; Bioinformatics; Biological; Biomedical Research; Communities; Computer Retrieval of Information on Scientific Projects Database; Computer software; Core Facility; DNA Microarray Chip; DNA Sequence; Data; Data Analyses; Databases; Electronics; Equipment; Equipment and supply inventories; Experimental Designs; Faculty; Funding; Gene Proteins; Genomics; Goals; Grant; HIV; Health Services Research; Housing; Human Resources; Institution; Journals; Literature; Mission; Molecular; Productivity; Proteomics; Publications; Reagent; Research; Research Personnel; Research Support; Resources; Services; Source; Speed; Students; Technical Expertise; Time; Training; Training Programs; United States National Institutes of Health; Women' s Health; base; computing resources; cost; data sharing; graduate student; innovation; medical schools; programs; protein expression; research study

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. NOTE: Tables and Figures were uploaded with the Overall Research Summary file. A. Specific Aims The mission of the Genomics and Proteomics Core is to provide the technical support and services for research faculty, graduate students and research support staff to perform innovative research on genes and proteins with special emphasis on the support of research in the areas of women health, AIDS, HIV, and related fields. The Core is multi-functional since this Core provides the equipment and technical expertise to perform experiments on gene and protein expression, the computational resources for data analysis and data sharing (i.e., bioinformatics) and access to the existing literature and databases to facilitate experimental design. The specific functions of the Genomics and Proteomics Core at Meharry are: 1) to provide to the research faculty, graduate students and research support staff of Meharry Medical College the necessary expert personnel and equipment to provide the services of automated DNA sequencing, DNA Microarray, and real-time PCR; 2) to stock an inventory of reagents for research and facilitate the purchase of molecular biological reagents for researchers; 3) to provide technical assistance and training in the use of shared equipment housed in the facility; 4) to increase the access to electronic information sources including electronic journals and remote databases using the capacity and speed of Internet2; 5) to provide the technical expertise, hardware and software for the analysis of genomic and proteomic data; and 6) to provide a program of training in genomics and proteomics for faculty, staff and graduate students. The ultimate goal of the Genomics and Proteomics Core is to provide services needed by the research community at Meharry to increase research productivity as evidenced by increased grants submission and acquisition and increased publication numbers by faculty. In summary, the primary purpose of the Genomics and Proteomics Core is to provide on a continuing basis services to enhance the capability of the researchers at Meharry Medical College to perform significant biomedical research. The major service activities of the Genomics and Proteomics Core are to provide accurate DNA sequence information rapidly and cost-effectively, provide technical assistance with the use of shared equipment housed in the Core and provide convenient access to molecular biological reagents. The specific goals for this component are: 1. To provide to the faculty, students and staff of Meharry Medical College the necessary expert personnel and equipment to provide the services of automated DNA sequencing, DNA microarray, and real-time PCR. 2. To provide technical assistance with the use of shared equipment housed in the Genomics and Proteomics Core. 3. To increase the access to electronic information sources including e-journals and remote databases. 4. To provide the technical expertise, hardware and software for the experimental design and analysis of genomic and proteomic data. 5. To provide a program of training in genomics and proteomics for faculty, staff and students.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 注意：将表和数字上传到了总体研究摘要文件中。 A.具体目标 基因组学和蛋白质组学核心的使命是为研究教师，研究生和研究支持人员提供技术支持和服务，以对基因和蛋白质进行创新研究，并特别强调在妇女健康，艾滋病，艾滋病，艾滋病毒和相关领域的研究方面的支持。 核心是多功能的，因为该核心为进行基因和蛋白质表达的实验，数据分析和数据共享（即生物信息学）的计算资源提供了实验，并访问了现有文献和数据库以促进实验设计。 Meharry的基因组学和蛋白质组学核心的特定功能是：1）为梅哈里医学院的研究教师，研究生和研究支持人员提供所需的专家人员和设备，以提供自动DNA测序，DNA微阵列和实时PCR的服务； 2）库存研究库存，并促进为研究人员购买分子生物试剂； 3）提供技术援助和培训，以使用设施中的共享设备； 4）使用Internet的容量和速度增加了对电子信息源的访问，包括电子期刊和远程数据库； 5）提供技术专长，硬件和软件，以分析基因组和蛋白质组学数据； 6）为教职员工和研究生提供基因组学和蛋白质组学培训计划。基因组学和蛋白质组学核心的最终目标是提供Meharry的研究社区所需的服务，以提高研究生产力，这可以通过增加的赠款提交和获取和教师的出版数量增加。 总之，基因组学和蛋白质组学核心的主要目的是在持续的基础服务中提供，以增强Meharry医学院的研究人员进行重要的生物医学研究的能力。基因组学和蛋白质组学核心的主要服务活动是快速和成本效益地提供准确的DNA序列信息，在使用核心中含有的共享设备的使用中提供技术援助，并为分子生物试剂提供方便的访问。该组件的具体目标是： 1。为了提供梅哈里医学院的学生和教职员工，提供必要的专家人员和设备，以提供自动DNA测序，DNA微阵列和实时PCR的服务。 2。在使用基因组学和蛋白质组学核心中包含的共享设备方面提供技术援助。 3。增加对电子信息源的访问，包括电子杂志和远程数据库。 4。为基因组和蛋白质组学数据的实验设计和分析提供技术专长，硬件和软件。 5。为教职员工和学生提供基因组学和蛋白质组学培训计划。