Device for Tooth Cleaning in Special Needs and Older Populations

特殊需要和老年人群的牙齿清洁设备

基本信息

批准号：
7789913
负责人：
Shiva Prasad Kotha
金额：
$ 24.09万
依托单位：
UNIVERSITY OF CONNECTICUT STORRS
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-09-25 至 2011-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7789913
关键词：
Acoustics Adult Affect Air Area Bacterial Counts Behavior Bite Calcium Calcium Carbonate Child Chronic Childhood Arthritis Clinical Research Contracts Coupled Degenerative polyarthritis Dental Dental Hygiene Dental caries Development Device or Instrument Development Devices Dimensions Drug Formulations Elderly Electronics Elements Excision Fiber Film Fluorescence Free Radicals Frequencies Future Gel Goals Hand Health Health Care Costs Healthy People 2010 Heating Human Hydroxyapatites In Vitro Incidence Individual Lead Letters Life Expectancy Manuals Measures Mechanics Microbial Biofilms Microbubbles Microscopic Microspheres Modality Molds Motion Nature Nutritional Older Population Oral Oral cavity Oral health Paraplegia Particulate Periodontal Diseases Physics Physiologic pulse Polyethylene Glycols Polyurethanes Population Predisposition Prevention Process Property Public Health Pulse Pressure Quality of life Radiation Reporting Research Personnel Sepharose Series Shapes Silicates Silicon Dioxide Societies Sodium Fluoride Staining method Stains Stream Streptococcus mutans Surface Systemic disease Temperature Testing Tooth Loss Tooth structure Toothbrushing Toothpaste Ultrasonic wave Ultrasonics Ultrasonography Water base calcium phosphate cohort cold temperature design functional status health disparity improved industry partner inorganic phosphate interest melting microbial nano novel oral care patient population pressure public health relevance tooth surface toothbrush

项目摘要

DESCRIPTION (provided by applicant): Good oral hygiene practices, such as brushing teeth regularly, are critical to maintaining dental and periodontal health. In special needs and older populations with reduced manual dexterity, brushing is not rigorous enough to maintain oral hygiene, leading to a higher incidence of caries and periodontal disease in these cohorts. Poor oral health not only affects nutritional and functional status adversely, it also has serious implications on quality of life with a potential increase in the susceptibility of these individuals to a number of systemic ailments. This provides the impetus to develop a novel, hands- free device for tooth cleaning, with the objective of improving oral and systemic health in special needs and older populations. In this proposal, we hypothesize that a novel hands-free ultrasound generating device coupled with specially formulated gels will be effective in removing dental biofilms in vitro. To test this hypothesis, we propose to: (1) Develop and test ultrasound-generating piezo-fiber based composite strips molded into a form that can be placed over the teeth and gums, in conjunction with gels that function to enhance the action of the ultrasound, and (2) Determine the efficacy of the device in cleaning of typodont and human teeth covered with an experimental biofilm in vitro as compared to conventional brushing. The scientific and technological novelty lies in developing and using specialized ultrasound strips combined with uniquely formulated gels placed adjacent to the teeth to achieve biofilm removal. The gels will serve to provide a medium for propagating ultrasonic pressure waves to tooth surfaces AND to reduce ultrasonic energies required to cause cavitations (microscopic bubbles) that then expand and contract rapidly next to tooth surfaces and serve to clean teeth. The rapid expansion and contraction of these microscopic bubbles provides the same energies as those generated by the motion of brushes against tooth surfaces and are expected to dislodge biofilm within a maximum of two minutes. A series of gels will be developed that will enhance the action of ultrasound and will function to clean and renew the tooth. We anticipate that a device will be developed which can be used to clean teeth in an effective manner and with results comparable to brushing. The development of this device has important public health implications, since it will improve oral and possibly systemic health in special needs and older populations, and may also reduce healthcare costs. PUBLIC HEALTH RELEVANCE: Cleaning of teeth by regular brushing is extremely important towards maintaining oral health, which in turn can impact on overall health. Many older individuals and special needs populations lack the hand mobility to effectively clean their teeth, leading to oral and possibly systemic disease. This causes significant public health disparities in these populations. This application proposes the development and testing of a novel hands-free toothcleaning device, using ultrasound in association with specially formulated gels. The successful development of such a device will have a major public health impact by improving oral and general health of older individuals and those with special needs. Such improvements in oral and general health will also decrease healthcare costs to society.

描述（由申请人提供）：良好的口腔卫生实践，例如定期刷牙，对于维持牙齿和牙周健康至关重要。在特殊需求和较旧的人体敏捷性中，刷牙的严格性不足以维持口腔卫生，从而导致龋齿和牙周疾病的发病率更高。口腔健康状况不佳不仅会对营养和功能状况产生不利影响，而且对生活质量也有严重的影响，这些人对这些人对许多系统性疾病的敏感性有可能提高。这为开发一种新颖，无动用的设备提供了用于清洁牙齿清洁的动力，目的是改善特殊需求和较旧人群的口服和系统健康。在此提案中，我们假设一种新型的免提超声产生装置以及特殊配方的凝胶将有效地在体外去除牙齿生物膜。为了检验该假设，我们建议：（1）开发和测试基于压电纤维的基于压电纤维的复合条，并结合凝胶，与凝胶相结合，可以在牙齿和牙龈上放置，以增强超声的作用，以增强超声的作用，（2）（2）确定与常规牙齿覆盖的设备在实验中的效果，并确定与实验性的效果相结合。科学和技术的新颖性在于开发和使用专门的超声带，并结合牙齿附近的独特配方凝胶，以实现生物膜去除。凝胶将提供一种向牙齿表面传播超声压力波的培养基，并减少引起空白（微观气泡）所需的超声波能量，然后在牙齿表面旁边迅速膨胀和收缩并清洁牙齿。这些显微镜气泡的快速膨胀和收缩提供了与刷子在牙齿表面运动产生的能量相同的能量，并有望在最多两分钟内将生物膜驱散。将开发一系列的凝胶，以增强超声的作用，并可以清洁和更新牙齿。我们预计将开发一种设备，该设备可用于以有效的方式清洁牙齿，并且结果与刷牙相当。该设备的开发具有重要的公共卫生影响，因为它将改善特殊需求和较旧人口的口服和系统健康，并且还可能降低医疗保健成本。公共卫生相关性：定期刷牙清洁牙齿对于维持口腔健康极为重要，这反过来又会影响整体健康。许多老年人和特殊需求人群缺乏有效清洁牙齿的手动性，导致口腔疾病甚至是全身性疾病。这会导致这些人群的重大公共卫生差异。该应用建议使用与特殊配方的凝胶结合的超声来开发和测试一种新型的免提润解装置。这种设备的成功开发将通过改善老年人和有特殊需要的人的口服和一般健康而产生重大的公共卫生影响。口腔和一般健康的这种改善也将降低社会的医疗保健成本。