Device for Tooth Cleaning in Special Needs and Older Populations

特殊需要和老年人群的牙齿清洁设备

基本信息

批准号：
7789913
负责人：
Shiva Prasad Kotha
金额：
$ 24.09万
依托单位：
UNIVERSITY OF CONNECTICUT STORRS
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-09-25 至 2011-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7789913
关键词：
Acoustics Adult Affect Air Area Bacterial Counts Behavior Bite Calcium Calcium Carbonate Child Chronic Childhood Arthritis Clinical Research Contracts Coupled Degenerative polyarthritis Dental Dental Hygiene Dental caries Development Device or Instrument Development Devices Dimensions Drug Formulations Elderly Electronics Elements Excision Fiber Film Fluorescence Free Radicals Frequencies Future Gel Goals Hand Health Health Care Costs Healthy People 2010 Heating Human Hydroxyapatites In Vitro Incidence Individual Lead Letters Life Expectancy Manuals Measures Mechanics Microbial Biofilms Microbubbles Microscopic Microspheres Modality Molds Motion Nature Nutritional Older Population Oral Oral cavity Oral health Paraplegia Particulate Periodontal Diseases Physics Physiologic pulse Polyethylene Glycols Polyurethanes Population Predisposition Prevention Process Property Public Health Pulse Pressure Quality of life Radiation Reporting Research Personnel Sepharose Series Shapes Silicates Silicon Dioxide Societies Sodium Fluoride Staining method Stains Stream Streptococcus mutans Surface Systemic disease Temperature Testing Tooth Loss Tooth structure Toothbrushing Toothpaste Ultrasonic wave Ultrasonics Ultrasonography Water base calcium phosphate cohort cold temperature design functional status health disparity improved industry partner inorganic phosphate interest melting microbial nano novel oral care patient population pressure public health relevance tooth surface toothbrush

项目摘要

DESCRIPTION (provided by applicant): Good oral hygiene practices, such as brushing teeth regularly, are critical to maintaining dental and periodontal health. In special needs and older populations with reduced manual dexterity, brushing is not rigorous enough to maintain oral hygiene, leading to a higher incidence of caries and periodontal disease in these cohorts. Poor oral health not only affects nutritional and functional status adversely, it also has serious implications on quality of life with a potential increase in the susceptibility of these individuals to a number of systemic ailments. This provides the impetus to develop a novel, hands- free device for tooth cleaning, with the objective of improving oral and systemic health in special needs and older populations. In this proposal, we hypothesize that a novel hands-free ultrasound generating device coupled with specially formulated gels will be effective in removing dental biofilms in vitro. To test this hypothesis, we propose to: (1) Develop and test ultrasound-generating piezo-fiber based composite strips molded into a form that can be placed over the teeth and gums, in conjunction with gels that function to enhance the action of the ultrasound, and (2) Determine the efficacy of the device in cleaning of typodont and human teeth covered with an experimental biofilm in vitro as compared to conventional brushing. The scientific and technological novelty lies in developing and using specialized ultrasound strips combined with uniquely formulated gels placed adjacent to the teeth to achieve biofilm removal. The gels will serve to provide a medium for propagating ultrasonic pressure waves to tooth surfaces AND to reduce ultrasonic energies required to cause cavitations (microscopic bubbles) that then expand and contract rapidly next to tooth surfaces and serve to clean teeth. The rapid expansion and contraction of these microscopic bubbles provides the same energies as those generated by the motion of brushes against tooth surfaces and are expected to dislodge biofilm within a maximum of two minutes. A series of gels will be developed that will enhance the action of ultrasound and will function to clean and renew the tooth. We anticipate that a device will be developed which can be used to clean teeth in an effective manner and with results comparable to brushing. The development of this device has important public health implications, since it will improve oral and possibly systemic health in special needs and older populations, and may also reduce healthcare costs. PUBLIC HEALTH RELEVANCE: Cleaning of teeth by regular brushing is extremely important towards maintaining oral health, which in turn can impact on overall health. Many older individuals and special needs populations lack the hand mobility to effectively clean their teeth, leading to oral and possibly systemic disease. This causes significant public health disparities in these populations. This application proposes the development and testing of a novel hands-free toothcleaning device, using ultrasound in association with specially formulated gels. The successful development of such a device will have a major public health impact by improving oral and general health of older individuals and those with special needs. Such improvements in oral and general health will also decrease healthcare costs to society.

描述（由申请人提供）：良好的口腔卫生习惯，例如定期刷牙，对于保持牙齿和牙周健康至关重要。在有特殊需要和手工灵活性下降的老年人群中，刷牙不够严格，无法保持口腔卫生，导致这些人群的龋齿和牙周病发病率较高。口腔健康状况不佳不仅会对营养和功能状态产生不利影响，还会对生活质量产生严重影响，可能会增加这些人对许多全身性疾病的易感性。这为开发一种新颖的免提牙齿清洁设备提供了动力，其目的是改善特殊需要和老年人群的口腔和全身健康。在该提案中，我们假设一种新型免提超声波发生装置与特殊配方的凝胶相结合将能够有效地在体外去除牙齿生物膜。为了检验这一假设，我们建议：（1）开发和测试基于超声波产生压电纤维的复合材料条，其模制成可以放置在牙齿和牙龈上的形状，并与凝胶一起使用，以增强牙齿和牙龈的作用。 (2) 与传统刷牙相比，确定该装置在体外清洁覆盖有实验性生物膜的牙痛和人类牙齿的功效。科学技术的新颖性在于开发和使用专门的超声波条与放置在牙齿附近的独特配方的凝胶相结合，以实现生物膜去除。凝胶将提供一种介质，用于将超声波压力波传播到牙齿表面，并减少引起空化（微小气泡）所需的超声波能量，然后空化在牙齿表面附近快速膨胀和收缩，从而清洁牙齿。这些微小气泡的快速膨胀和收缩提供了与刷子在牙齿表面运动时产生的能量相同的能量，预计最多两分钟内即可去除生物膜。将开发一系列凝胶，增强超声波的作用，并起到清洁和更新牙齿的作用。我们预计将开发出一种能够有效清洁牙齿的装置，其效果可与刷牙相媲美。该设备的开发具有重要的公共卫生影响，因为它将改善特殊需求和老年人群的口腔健康和可能的全身健康，并且还可能降低医疗费用。公共卫生相关性：定期刷牙清洁牙齿对于保持口腔健康极其重要，进而影响整体健康。许多老年人和特殊需要人群缺乏有效清洁牙齿的手部活动能力，导致口腔疾病和可能的全身疾病。这导致这些人群的公共卫生状况存在显着差异。该申请建议开发和测试一种新型免提牙齿清洁装置，该装置使用超声波与特殊配制的凝胶相结合。这种设备的成功开发将改善老年人和有特殊需要的人的口腔和整体健康，从而对公共健康产生重大影响。口腔和全身健康的这种改善也将降低社会的医疗费用。