Impacts of Early Life Food Insecurity on Child Obesity and Cognitive Development Trajectories

生命早期粮食不安全对儿童肥胖和认知发展轨迹的影响

• 批准号: 10643718
• 负责人: Eliza W. Kinsey
• 金额: $ 15.62万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-01-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10643718
• 关键词: Adolescence; Adolescent; Adolescent obesity; Adult; Age; Anxiety; Attention; Award; Birth; Body Composition; Body mass index; Brain; Child; Child Rearing; Childhood; Cognition; Cognitive; Cohort Studies; Collection; Complex; Data; Data Analyses; Data Collection; Development; Diagnostic tests; Emotional; Enrollment; Environment; Environmental Health; Epidemiologic Methods; Epidemiology; Family; Food; Food Assistance Programs; Generations; Goals; Growth; Growth and Development function; Health Food; Health Policy; Health Status; Household; Intervention; Knowledge; Life; Link; Liquid substance; Long-Term Effects; Longitudinal cohort study; Low income; Magnetic Resonance Imaging; Measurement; Measures; Mentorship; Methods; Mothers; Motor; Newborn Infant; Obesity; Pathway interactions; Phase; Policies; Pregnancy; Psyche structure; Public Health; Public Health Schools; Research; Role; Scientist; Screening procedure; Social Policies; Special Supplemental Nutrition Program for Women, Infants, and Children; Stress; Supervision; Surveys; System; Teenagers; Testing; Time; Training; Translations; Urban Health; Woman; Work; Youth; abdominal fat; active lifestyle; career; career development; cognitive control; cognitive development; cognitive function; cognitive load; cognitive testing; cohort; community partnership; design; diagnostic screening; early childhood; epidemiology study; evidence based guidelines; experience; follow-up; food insecurity; food marketing; food security; health of the mother; healthy lifestyle; indexing; insight; maternal obesity; middle childhood; novel; nutrition; obesity development; obesity in children; postnatal; prenatal; psychosocial; skills; young adult

PROJECT SUMMARY/ABSTRACT Food insecurity is a significant public health concern and is defined as limited or uncertain access to enough food for an active and healthy lifestyle. Food insecurity impacts 15.7% of households with children in the U.S., but its effects on child growth and developmental trajectories are not well documented. In this K99/R00 Pathway to Independence Award project, I propose research aims to better understand the impact of early life food insecurity on child growth and development. I will utilize data from two ongoing birth cohort studies at the Columbia Center for Children's Environmental Health (CCCEH) to assess the effects of food insecurity during pregnancy and intermittent and persistent food insecurity during early childhood on 1) maternal obesity and cognitive function, and 2) childhood growth and cognitive development trajectories from early childhood to age 18. This will be the first study to simultaneously examine the role of food insecurity trajectories in child and adolescent cognitive development and obesity. This research will combine cutting edge body composition measurement, cognitive assessment and epidemiologic methods and will contribute important substantive knowledge on the food insecurity-obesity and the food insecurity-cognitive function associations within children and adolescents. This work will also provide novel insight to inform evidence-based recommendations and interventions around child and adolescent obesity. During the K99 phase, my work will be situated within the top- tier research environments of Columbia's Mailman School of Public Health, the CCCEH and the NY Obesity Research Center, all of which have a strong focus on policy translation and community partnerships. Situating my K99/R00 work in a research environment focused on policy translation and analysis will provide me with experience and training in how research findings and data can contribute to policy debates and to the generation of new data driven policies. The training goals of this K99/R00 are to become skilled in complex longitudinal data analyses, body composition assessment in children and adolescents using bio-impedance and magnetic resonance imaging, child cognitive development assessment using diagnostic tests, and collection and analysis of quantitative data within a birth cohort. As part of the R00 phase, I will gain field experience in collecting anthropometric and cognitive data from children. This work is a logical extension of my prior and ongoing research in obesity, nutrition and food insecurity, and will fill gaps in training that I need to launch my career as an independent scientist working at the intersection of epidemiology, urban health and social policy.

项目概要/摘要 粮食不安全是一个重大的公共卫生问题，被定义为获得足够食物的机会有限或不确定 积极健康生活方式的食物。粮食不安全影响了美国 15.7% 有孩子的家庭， 但其对儿童生长和发育轨迹的影响尚无充分记录。在这个 K99/R00 途径中 对于独立奖项目，我建议研究旨在更好地了解早期食物的影响 儿童成长和发展的不安全感。我将利用两项正在进行的出生队列研究的数据 哥伦比亚儿童环境健康中心 (CCCEH) 评估粮食不安全的影响 怀孕以及幼儿期间歇性和持续性粮食不安全 1) 孕产妇肥胖和 认知功能，2) 儿童成长和从幼儿期到年龄的认知发展轨迹 18. 这将是第一项同时考察粮食不安全轨迹对儿童和儿童的影响的研究。 青少年认知发展和肥胖。这项研究将结合最先进的身体成分 测量、认知评估和流行病学方法，将为重要的实质性贡献 关于儿童的粮食不安全-肥胖和粮食不安全-认知功能关联的知识 和青少年。这项工作还将提供新颖的见解，为基于证据的建议和 针对儿童和青少年肥胖的干预措施。在K99阶段，我的工作将位于最顶层—— 哥伦比亚梅尔曼公共卫生学院、CCCEH 和纽约肥胖研究所的一级研究环境 研究中心，所有这些都非常注重政策转化和社区伙伴关系。定位 我在专注于政策翻译和分析的研究环境中的 K99/R00 工作将为我提供 研究结果和数据如何为政策辩论和一代做出贡献的经验和培训 新的数据驱动政策。这个K99/R00的训练目标是熟练掌握复杂的纵向数据 使用生物阻抗和磁力分析、儿童和青少年的身体成分评估 共振成像、使用诊断测试评估儿童认知发展以及收集和分析 出生队列中的定量数据。作为 R00 阶段的一部分，我将获得收集方面的现场经验 来自儿童的人体测量和认知数据。这项工作是我之前和正在进行的工作的逻辑延伸 肥胖、营养和粮食不安全方面的研究，并将填补我开展职业生涯所需的培训空白 一位独立科学家，致力于流行病学、城市健康和社会政策的交叉领域。