T32 CTEng (Cellular and Tissue Engineering) Training Program

T32 CTEng（细胞和组织工程）培训计划

• 批准号: 10641891
• 负责人: Edward A. Botchwey
• 金额: $ 47.75万
• 依托单位: GEORGIA INSTITUTE OF TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10641891
• 关键词: Tissue Engineering; Training Programs; cellular engineering

Project Summary This application requests funding for Years 31-35 of our highly successful and impactful NIGMS Biotechnology T32 Program on Cell and Tissue Engineering (CTEng). The objective of CTEng is to provide innovative and integrated training for predoctoral engineering students in cell and tissue engineering to develop future leaders for these biotechnology industries. CTEng will provide an innovative and integrated training program comprising (i) formal courses on engineering fundamentals, biosciences, bioengineering, and business principles; (ii) bi-weekly meetings with faculty with topics rotating among journal club discussion, research presentation, faculty and industry career discussions, and mentorship training; (iii) industrial visits and internships; (iii) an industry mentor program; (iv) an annual cell and tissue engineering conference; (v) a regional T32 Biotechnology career development workshop; and (vi) training in the responsible conduct of research and methods for enhancing reproducibility. Georgia Tech provides an outstanding, highly collaborative and integrative training and research environment in cell and tissue engineering. The particular strengths, and in many instances unique features, of our program include (1) one of the largest faculties in the nation, comprising many of the leading researchers in cell and tissue engineering, who provide a dynamic, broad and deep critical mass of expertise; (2) recognized leadership in engineering and medicine (with our partner Emory University School of Medicine) and especially at their intersection; (3) outstanding research facilities and infrastructure; (4) a curriculum of innovative training components emphasizing developing interdisciplinary researchers with strong leadership and communication skills; (5) a dynamic ecosystem with multi-faceted connection points to industry and entrepreneurship and commercialization; (6) a richly diverse and supportive culture; and (7) quality programs for the recruitment, training and graduation of underrepresented minority students that are among the largest and most successful in the nation. CTEng preceptors will nominate predoctoral students from our BioEngineering, joint GT/Emory Biomedical Engineering, Chemical and Biomolecular Engineering, and Mechanical Engineering programs at the end of their first year, and CTEng will support selected trainees for the second and third years of graduate school. We request support for 9 students per year, which is the current funding level. Graduates of CTEng will exhibit high research productivity in terms of publications and presentations and will transition into impactful careers in academic, industry, and government and become leaders of the cell and tissue engineering biotechnology industries.

项目概要 此申请要求为我们非常成功和有影响力的 NIGMS 的第 31-35 年提供资金 细胞和组织工程生物技术 T32 计划 (CTEng)。 CTEng 的目标是 为博士前工科学生提供细胞和细胞方面的创新和综合培训 组织工程为这些生物技术行业培养未来的领导者。 CTEng 将 提供创新和综合的培训计划，包括（i）正规工程课程 基础知识、生物科学、生物工程和商业原理； (ii) 每两周与教师举行一次会议 主题在期刊俱乐部讨论、研究报告、教师和行业职业之间轮换 讨论和指导培训； (iii) 工业参观和实习； (iii) 行业导师 程序; (iv) 年度细胞和组织工程会议； (v) 区域性 T32 生物技术职业 开发研讨会； (vi) 负责任地开展研究和方法方面的培训 提高再现性。佐治亚理工学院提供了出色的、高度协作和综合的 细胞和组织工程的培训和研究环境。特殊的优势，并且在许多方面 我们项目的独特之处包括（1）全国最大的院系之一， 由细胞和组织工程领域的许多领先研究人员组成，他们提供了动态的、 广泛而深入的专业知识； (2) 工程和医学领域公认的领导地位（ 我们的合作伙伴埃默里大学医学院），特别是在它们的交叉点； （三）突出 研究设施和基础设施； (4) 课程创新训练内容强调 培养具有强大领导力和沟通能力的跨学科研究人员； (5) 动态 与产业、创业等多方面连接的生态系统 商业化； (6) 丰富多样且支持性的文化； (7) 质量计划 招收、培训和毕业人数最多的少数族裔学生 也是全国最成功的。 CTEng 导师将提名我们的博士前学生 生物工程、GT/Emory 联合生物医学工程、化学和生物分子工程，以及 机械工程课程在第一年结束时，CTEng 将支持选定的 研究生院第二年和第三年的实习生。我们请求每年为 9 名学生提供支持， 这是当前的资金水平。 CTEng 的毕业生将在以下方面表现出较高的研究生产力 的出版物和演讲，并将转变为学术、工业和领域有影响力的职业 政府并成为细胞和组织工程生物技术行业的领导者。

项目成果

Label-free microfluidic isolation of functional and viable lymphocytes from peripheral blood mononuclear cells.

从外周血单核细胞中无标记微流体分离功能性和活性淋巴细胞。

• DOI: 10.1063/5.0161047
• 发表时间: 2023-09-01
• 期刊: Biomicrofluidics
• 影响因子: 3.2
• 作者: Abhishek Raj;Katily Ramirez;Katherine M. Young;Nicholas E. Stone;Peter Shankles;Mehdia Nadeem Rajab Ali;Anthony Malik Compton;Wilbur A. Lam;Ale;er Alexeev;er;Todd Sulchek
• 通讯作者: Todd Sulchek

Integrative Analysis of Cytokine and Lipidomics Datasets Following Mild Traumatic Brain Injury in Rats.

大鼠轻度创伤性脑损伤后细胞因子和脂质组学数据集的综合分析。

• 发表时间: 2024-02-21
• 影响因子: 4.1
• 作者: Pulliam, Alexis N;Pybus, Alyssa F;Gaul, David A;Moore, Samuel G;Wood, Levi B;Fernández, Facundo M;LaPlaca, Michelle C
• 通讯作者: LaPlaca, Michelle C

Comparing Brain and Blood Lipidome Changes following Single and Repetitive Mild Traumatic Brain Injury in Rats.

比较大鼠单次和重复轻度创伤性脑损伤后大脑和血液脂质组的变化。

• 发表时间: 2024-01-17
• 影响因子: 5
• 作者: Pulliam, Alexis N;Gier, Eric C;Gaul, David A;Moore, Samuel G;Fernández, Facundo M;LaPlaca, Michelle C
• 通讯作者: LaPlaca, Michelle C