Annual Adult Changes in Thought (ACT) symposium on aging, dementia, and Alzheimer's disease

关于衰老、痴呆和阿尔茨海默病的年度成人思想变化 (ACT) 研讨会

• 批准号: 10227230
• 负责人: Dori E Rosenberg
• 金额: $ 5万
• 依托单位: KAISER FOUNDATION RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-01 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10227230
• 关键词: Adult; Aging; Alzheimer' s Disease; Alzheimer' s Disease patient registry; Alzheimer' s disease brain; Alzheimer' s disease related dementia; British; Clinical; Collaborations; Communities; Consultations; DNA; Data; Dementia; Discipline; Disease; Early Diagnosis; Elderly; Equipment; Evaluation; Feedback; Funding; Future; Grant; Image; Infrastructure; Institution; Internal Medicine; International; Journals; Laboratories; Learning; Medical; Medicine; Methods; Mind; Minority Groups; National Institute on Aging; Neurobiology; Neurology; New England; Paper; Prevention; Principal Investigator; Publishing; Research; Research Personnel; Resources; Scientist; Time; Traumatic Brain Injury; Travel; Underrepresented Minority; Universities; Washington; Woman; Work; aging brain; brain tissue; data sharing; human old age (65+); innovation; molecular phenotype; research study; resilience; symposium; trend

Project Summary/Abstract Nearly 6 million U.S. adults are currently living with Alzheimer’s disease (AD), and 700,000 of these people will die in 2019 alone. There is no simple solution for prevention, early detection, or cure. Since 1994, the Adult Changes in Thought (ACT) study has collected observational, clinical, and laboratory data on more than 5,500 older adults and is following them over time for signs of dementia and Alzheimer’s disease. ACT data contribute to a living, learning laboratory, which serves as a scientific resource for the research community. For the past seven years, we have held an annual ACT symposium to showcase new ACT resources, highlight innovative research findings, share new grant ideas, and promote cross-disciplinary collaborations. Every year we have received higher ratings on our post-symposium evaluations, with 98% of last year’s attendees indicating they would recommend the symposium to others and 100% indicating they would attend a future ACT symposium. However, we do not have the capacity to hold future symposia without conference grant funding. This conference grant will provide support to continue and grow the ACT symposia over the next five years. The specific objectives of our conference grant are to: 1) promote scientific use and understanding of ACT data; 2) promote collaborations across scientific disciplines, institutions, and studies; and 3) provide opportunities for feedback on ongoing and planned work such as analyses-in-progress or new grant ideas, particularly for junior investigators. This funding will allow us to host the symposium in a large, accessible venue with advanced audiovisual equipment. It also will provide travel stipends for junior researchers, investigators from underrepresented minority groups, and researchers traveling from out of town so that we may extend our reach to new external investigators. Future conferences will cover critical topics in aging and dementia research such as resilience, imaging, dementia subtypes, molecular phenotypes, traumatic brain injury, and others. Long term, continuing and expanding the ACT symposia will increase use of the ACT living laboratory and provide a creative, welcoming space for top investigators to exchange innovative research ideas and accelerate AD and brain aging research.

项目概要/摘要 目前有近 600 万美国成年人患有阿尔茨海默病 (AD)，其中 70 万人将罹患阿尔茨海默病 (AD) 自 2019 年以来，没有简单的预防、早期发现或治疗方法。 思想转变 (ACT) 研究收集了超过 5,500 项研究的观察、临床和实验室数据 老年人，并随着时间的推移跟踪他们的痴呆症和阿尔茨海默病迹象。 为一个生活、学习的实验室做出贡献，该实验室作为研究界的科学资源。 过去七年，我们每年举办ACT研讨会，展示新的ACT资源，突出 每年都有创新的研究成果，分享新的资助想法，并促进跨学科合作。 我们在会后评估中获得了更高的评价，去年与会者的评分为 98% 表示他们会向其他人推荐该研讨会，并 100% 表示他们会参加未来的研讨会 然而，如果没有会议拨款，我们没有能力举办未来的研讨会。 这笔会议拨款将为 ACT 研讨会在未来五年内继续和发展提供支持。 我们会议拨款的​​具体目标是： 1) 促进科学利用和理解 ACT 数据；2) 促进跨科学学科、机构和研究的合作；3) 提供 对正在进行的和计划的工作（例如正在进行的分析或新的资助想法）提供反馈的机会， 特别是对于初级研究人员来说，这笔资金将使我们能够在一个大型、方便的地方举办研讨会。 它还将为初级研究人员提供旅行津贴， 来自代表性不足的少数群体的调查员和来自外地的研究人员，以便我们 可能会将我们的影响范围扩大到新的外部研究人员。未来的会议将涵盖老龄化和老龄化方面的关键主题。 痴呆症研究，例如复原力、成像、痴呆亚型、分子表型、创伤性脑 从长远来看，继续并扩大 ACT 研讨会将增加 ACT 生活的使用。 实验室，为顶尖研究人员交流创新研究提供一个富有创意、热情的空间 想法并加速 AD 和脑衰老研究。