Cancer Research Informatics and Services

癌症研究信息学和服务

• 批准号: 7698824
• 负责人: LYNNE T PENBERTHY
• 金额: $ 2.5万
• 依托单位: VIRGINIA COMMONWEALTH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-03 至 2011-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7698824
• 关键词: Basic Science; Biostatistics Shared Resource; Cancer Center; Cancer Hospital; Clinical; Clinical Research; Clinical Trials; Clinical Trials Database; Communities; Complex; Computer software; Data; Data Set; Data Sources; Databases; Development; Documentation; Electronics; Eligibility Determination; Environment; Grant; Health Services Research; Healthcare Systems; Hospitals; Human Resources; Informatics; Information Systems; Inpatients; Link; Malignant Neoplasms; Medical Informatics; Numbers; Operative Surgical Procedures; Outpatients; Pathology Report; Patients; Population; Preparation; Principal Investigator; Process; Protocols documentation; Range; Research; Research Personnel; Research Support; Resource Sharing; Resources; Screening procedure; Services; Source; Standards of Weights and Measures; Support of Research; System; anticancer research; base; cancer prevention; commercial application; demographics; design; falls; genetic linkage analysis; neoplasm registry; response

The CRIS Shared Resource serves as both a medical informatics and as a.service core. It consists of four main components: the Massey Cancer Center Information System (MCCIS), the Automated Cancer Extraction (ACE) Application, the Clinical Trials Eligibility Database (CTED), and the clinical research database system (Oncore¿). With the exception of Oncore¿, each component has been developed at VCU and is linked both technologically in terms of interrelated data sources and software as well as functionally in terms of personnel and services provided. The system design is based on inter-operability and community standards, with potential extensibility a strong development consideration. The core data come from linkage of multiple electronic sources across the VCU health care system including: inpatient and outpatient facilities, and the MCC In addition, primary data entered by research staff are a component of the CTED and Oncore¿. The data from the core are available and downloadable both as source documents (such as original surgical pathology reports) and as analyzable datasets developed by core personnel to answer specific research questions. In addition to the data, consultative and analytic services are provided through this Shared Resource. These services range from providing population numbers for grant preparation to linkage and analysis of complex data sets developed in response to investigator requests. The MCCIS is the oldest component of the core, originally developed in 1998, with the linkage of VCU claims data for inpatient and outpatient services. The MCCIS serves as the primary component providing analysis services, linking and utilizing data from the MCCIS and the other three core components for these analyses. The ACE application is the newest component and was implemented in December of 2006. ACE serves as the initial processing system for screening messages for cancer relevance and for storage of all electronic sources from the VCUHS and linking the data to CTED and the hospital cancer registry. The most recent SQL Server version of CTED was implemented in April of 2007. The commercial application used for administrative and clinical research in tracking of oversight and clinical trials activity was implemented in 2005. Currently, integration and equivalency of Oncore¿ with the other three components is being developed to provide autouploading of key information such as demographics, as well as direct access to source documentation from the other three components of CRIS for research staff while in the Oncore¿ environment.

CRIS共享的资源既是医疗信息，又是服务核心。它由四个 主要组成部分：梅西癌症中心信息系统（MCCI），自动癌 提取（ACE）应用，临床试验资格数据库（CTED）和临床研究 数据库系统（ONCORE�）。除了OnCore¿，每个组件都是在VCU上开发的 并以相互关联的数据源和软件以及功能在技术上链接 提供的人员和服务条款。系统设计基于互操作性和社区 标准，潜在的可扩展性是强大的发展考虑因素。核心数据来自链接 VCU医疗保健系统中多个电子资源的包括：住院和门诊设施， 此外，研究人员输入的主要数据是CTED的组成部分， ONCORE¿。来自核心的数据可作为源文档可用，并且可下载 原始手术病理报告）和核心人员开发的可分析数据集以回答 具体的研究问题。除数据外，还通过 这个共享资源。这些服务范围从提供授予准备的人口数量到 响应研究者请求而开发的复杂数据集的链接和分析。麦基斯是 核心最古老的组成部分最初于1998年开发，VCU的链接索取了住院的数据 和门诊服务。 MCCI是提供分析服务的主要组件，链接 并使用来自MCCI的数据和其他三个核心组件进行这些分析。王牌 应用是最新组件，于2006年12月实施。ACE用作初始 用于筛查癌症相关性和存储所有电子资源的处理系统的处理系统 从VCUHS到将数据与CTED和医院癌症注册处联系起来。最新的SQL Server CTED版本于2007年4月实施。用于行政和 2005年实施了有关监督和临床试验活动的追踪和临床试验活动的临床研究。 正在开发与其他三个组成部分的集成和等效性 关键信息（例如人口统计信息）以及从中直接访问源文档 在OnCore环境中，研究人员的CRIS的其他三个组成部分。