Cancer Research Informatics and Services

癌症研究信息学和服务

• 批准号: 7698824
• 负责人: LYNNE T PENBERTHY
• 金额: $ 2.5万
• 依托单位: VIRGINIA COMMONWEALTH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-03 至 2011-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7698824
• 关键词: Basic Science; Biostatistics Shared Resource; Cancer Center; Cancer Hospital; Clinical; Clinical Research; Clinical Trials; Clinical Trials Database; Communities; Complex; Computer software; Data; Data Set; Data Sources; Databases; Development; Documentation; Electronics; Eligibility Determination; Environment; Grant; Health Services Research; Healthcare Systems; Hospitals; Human Resources; Informatics; Information Systems; Inpatients; Link; Malignant Neoplasms; Medical Informatics; Numbers; Operative Surgical Procedures; Outpatients; Pathology Report; Patients; Population; Preparation; Principal Investigator; Process; Protocols documentation; Range; Research; Research Personnel; Research Support; Resource Sharing; Resources; Screening procedure; Services; Source; Standards of Weights and Measures; Support of Research; System; anticancer research; base; cancer prevention; commercial application; demographics; design; falls; genetic linkage analysis; neoplasm registry; response

The CRIS Shared Resource serves as both a medical informatics and as a.service core. It consists of four main components: the Massey Cancer Center Information System (MCCIS), the Automated Cancer Extraction (ACE) Application, the Clinical Trials Eligibility Database (CTED), and the clinical research database system (Oncore¿). With the exception of Oncore¿, each component has been developed at VCU and is linked both technologically in terms of interrelated data sources and software as well as functionally in terms of personnel and services provided. The system design is based on inter-operability and community standards, with potential extensibility a strong development consideration. The core data come from linkage of multiple electronic sources across the VCU health care system including: inpatient and outpatient facilities, and the MCC In addition, primary data entered by research staff are a component of the CTED and Oncore¿. The data from the core are available and downloadable both as source documents (such as original surgical pathology reports) and as analyzable datasets developed by core personnel to answer specific research questions. In addition to the data, consultative and analytic services are provided through this Shared Resource. These services range from providing population numbers for grant preparation to linkage and analysis of complex data sets developed in response to investigator requests. The MCCIS is the oldest component of the core, originally developed in 1998, with the linkage of VCU claims data for inpatient and outpatient services. The MCCIS serves as the primary component providing analysis services, linking and utilizing data from the MCCIS and the other three core components for these analyses. The ACE application is the newest component and was implemented in December of 2006. ACE serves as the initial processing system for screening messages for cancer relevance and for storage of all electronic sources from the VCUHS and linking the data to CTED and the hospital cancer registry. The most recent SQL Server version of CTED was implemented in April of 2007. The commercial application used for administrative and clinical research in tracking of oversight and clinical trials activity was implemented in 2005. Currently, integration and equivalency of Oncore¿ with the other three components is being developed to provide autouploading of key information such as demographics, as well as direct access to source documentation from the other three components of CRIS for research staff while in the Oncore¿ environment.

CRIS 共享资源既作为医疗信息学又作为服务核心，它由四个部分组成。 主要组成部分：梅西癌症中心信息系统（MCCIS）、自动化癌症 提取 (ACE) 申请、临床试验资格数据库 (CTED) 和临床研究 数据库系统（Oncore¿）。 ，每个组件都是在 VCU 开发的 并且在相互关联的数据源和软件方面以及在功能方面都具有技术联系 系统设计基于互操作性和社区。 标准，具有潜在的可扩展性，是强有力的开发考虑，核心数据来自联动。 VCU 医疗保健系统中的多个电子来源，包括：住院和门诊设施， 此外，研究人员输入的原始数据是 CTED 和 MCC 的组成部分 Oncore¿核心数据均可作为源文档提供和下载（例如. 原始手术病理报告）以及核心人员开发的可分析数据集来回答 除了数据之外，还通过以下方式提供咨询和分析服务。 这些服务的范围从提供赠款准备的人口数量到 MCCIS 是根据研究者的要求开发的复杂数据集的链接和分析。 核心中最古老的组件，最初开发于 1998 年，与住院病人的 VCU 索赔数据相链接 MCCIS 是提供分析服务、链接的主要组成部分。 并利用来自 MCCIS 和其他三个核心组件的数据进行这些分析。 应用程序是最新的组件，于 2006 年 12 月实施。ACE 作为最初的组件 用于筛选癌症相关信息和存储所有电子资源的处理系统 来自 VCUHS 并将数据链接到 CTED 和医院癌症登记处最新的 SQL Server。 CTED版本于2007年4月实施。商业应用程序用于行政和 临床研究跟踪监督和临床试验活动于 2005 年实施。目前， Oncore 的集成和等效性¿正在开发其他三个组件以提供自动上传功能 人口统计等关键信息，以及直接访问源文档 研究人员在 Oncore 时使用 CRIS 的其他三个组成部分¿环境。