Core D – Biostatistics Core

核心 D — 生物统计学核心

• 批准号: 10441218
• 负责人: Hong Li
• 金额: $ 7.48万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10441218
• 关键词: Address; Basic Science; Biometry; Biostatistics Core; Biostatistics Shared Resource; Cancer Center; Communication; Complex; Data; Data Analyses; Data Analytics; Data Collection; Data Display; Ensure; Evaluation Research; Faculty; Fertilization; Formulation; Fostering; Generations; Human Resources; Investigation; Logistics; Maintenance; Malignant neoplasm of pancreas; Manuscripts; Medical; Oncology; Outcome; Output; Positioning Attribute; Preparation; Procedures; Program Research Project Grants; Publications; Reporting; Research; Research Design; Research Personnel; Resources; Role; Sample Size; Security; Services; South Carolina; Statistical Data Interpretation; Statistical Methods; Statistical Models; Testing; Translational Research; Universities; Visual; base; cancer cachexia; complex data; computerized data processing; data analysis pipeline; data exchange; data exploration; data integration; data management; data quality; data sharing; design; experimental study; member; novel; power analysis; programs; repository; statistics; success; tool

SUMMARY: CORE D The Biostatistics Core provides centralized and state-of-the-art support to meet the data management and analytic needs of the Program Project Grant. Core personnel have the necessary expertise in statistics to optimize the quantitative demands of the aims outlined in each project. Core centralization fosters bonds and communication between project leaders and statisticians, and facilitates matching of investigators with the most appropriate quantitative collaborators. In addition, centralizing this resource ideally positions the Core to initiate and promote interdisciplinary interactions among projects, and thus contributes to accelerating the bi -directional exchange between basic and translational science. Core personnel can also help investigators design new studies and test new hypotheses that may arise by cross-fertilization among related projects. The Core will be staffed by two statisticians, Dr. Hong Li (Core Leader) and Mr. Kent Armeson. Core biostatisticians are housed in the Biostatistics Shared Resource in the Hollings Cancer Center (HCC) at the Medical University of South Carolina (MUSC), an active and committed group of biostatistics faculty members broadly skilled in statistical methods in oncology research. By situating key Core personnel in MUSC’s HCC, all projects are guaranteed access to a robust tool kit to support quantitative needs. All Projects require support with respect to: experimental study design, including power analysis and sample size justification ; data collection, storage, and analysis; interpretation of output from complex statistical methods; and abstract and manuscript preparation. By providing research expertise and logistical support to the quantitative needs of each project, the Biostatistic s Core will contribute to professional, efficient and rigorous procedures for the generation, analysis and interpretation of data, which will be critical to the success of the Program Project Grant.

摘要：核心d 生物统计学核心提供集中式和最先进的支持，以满足数据管理和 计划项目赠款的分析需求。核心人员在统计方面具有必要的专业知识 优化每个项目中概述的目标的定量要求。核心集中化促进债券和 项目负责人与统计学家之间的沟通，并促进调查人员的匹配 适当的定量合作者。此外，在理想情况下，集中该资源是启动的核心 并促进项目之间的跨学科互动，从而有助于加速双向 基础科学和转化科学之间的交流。核心人员还可以帮助调查人员设计新的 研究和检验相关项目之间交叉利用可能引起的新假设。核心将是 由两位统计学家Hong Li（核心负责人）和Kent Armeson先生组成。核心生物统计学家被安置 在南方医科大学Hollings癌症中心（HCC）的生物统计学共享资源中 卡罗来纳州（MUSC），一群积极且致力于生物统计学的教职员工，广泛地熟练统计 肿瘤学研究中的方法。通过将关键核心人员置于MUSC的HCC中，可以保证所有项目 访问强大的工具套件以支持定量需求。所有项目都需要支持以下方面的支持 研究设计，包括功率分析和样本量合理；数据收集，存储和分析； 解释复杂统计方法的产出；以及抽象和手稿的准备。通过提供 研究专业知识和后勤支持每个项目的定量需求，生物统计学的核心将 为生成，分析和解释的专业，高效和严格的程序做出贡献 数据，这对于计划项目赠款的成功至关重要。