MAPP Research Network Tissue Analysis and Technology Core

MAPP 研究网络组织分析和技术核心

• 批准号: 10217103
• 负责人: M. Scott Lucia
• 金额: --
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-09 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10217103
• 关键词: Archives; Biological; Biological Specimen Banks; Chronic; Chronic Prostatitis; Clinical; Clinical Trials Design; Code; Collection; Colorado; Data; Data Analyses; Data Collection; Development; Enrollment; Ensure; Epidemiology; Etiology; Funding; Goals; Interstitial Cystitis; Manuscripts; Measurement; Measures; National Institute of Diabetes and Digestive and Kidney Diseases; Natural History; Pain Disorder; Pain Research; Participant; Pattern; Phase; Phenotype; Physiological; Preparation; Procedures; Process; Protocols documentation; Research; Research Personnel; Residual state; Resources; Risk Factors; Shipping; Site; Specimen; Symptoms; System; Technology; Time; Tissues; United States National Institutes of Health; Universities; Woman; Work; biobank; biological specimen archives; chronic painful condition; chronic pelvic pain; clinically relevant; data repository; follow-up; improved; interdisciplinary approach; meetings; men; patient subsets; recruit; repository; response; sample collection; symptom management; trend; urologic; urologic chronic pelvic pain syndrome; working group

The TATC at the University of Colorado will continue to provide expertise and resources in support of the MAPP‐RN during the proposed MAPP‐Phase II extension period. The TATC was established to assist the MAPP‐RN with biospecimen collection, processing, and analyses. The TATC will work closely with the MAPP Executive and Steering Committees, the NIDDK, the Discovery Site Teams, and the Data Coordinating Core to ensure that the goals of the MAPP RN are met. The TATC will meet all NIH quality standards and will work closely with the DCC and the NIDDK Central Repository to coordinate eventual transfer of all residual biospecimens and ancillary data to the Central Repository before the end of the three‐year extension period. The current funding period ends in June 2019. We propose a three‐year funding extension, through June 2022 to accomplish the following: SPECIFIC AIM 1 Provide Biorepository Support to the MAPP RN. The TATC will continue to act as the central repository during the extended 12-month follow up window for all biospecimens collected in the SPS study and provide biospecimen collection kits, procedural guidance on specimen collection, handling, centralized processing, and archiving in support of MAPP-II. SPECIFIC AIM 2: Collaborate with the DCC on specimen-associated data collection and tracking. We will continue to closely collaborate with the Data Coordination Core (DCC) on best practices for data collection, specimen tracking and storage, and to support technical processes between the two cores, as well as coordinate procedures for coding, shipping, processing, receipt, storage of specimens, and the transfer of biospecimens and study data to the NIDDK Central Data and Specimen Repositories. SPECIFIC AIM 3: To continue participation in the Working Groups and in data analysis and manuscript preparation in support of MAPP-RN. We will continue to participate in the MAPP Executive and Steering committee meetings and calls. We will continue to be active partcipants in the MAPP RN Working Groups to collaborate on idea and hypothesis development, data analysis and manuscript preparation.

科罗拉多大学 TATC 将继续提供专业知识和资源来支持 MAPP-RN 在拟议的 MAPP-第二阶段延长期内，设立 TATC 是为了协助 MAPP-RN 生物样本采集、处理和分析。 TATC 将与 MAPP 执行和指导委员会、NIDDK、发现站点密切合作 团队和数据协调核心，以确保实现 MAPP RN 的目标 TATC 将满足所有要求。 NIH 质量标准，并将与 DCC 和 NIDDK 中央存储库密切合作，最终进行协调 在三年结束之前将所有残留的生物样本和辅助数据转移到中央存储库 延长期。 目前的资助期将于 2019 年 6 月结束。我们建议将资助期限延长三年，直至 2022 年 6 月 完成以下任务： 具体目标 1 为 MAPP RN 提供生物样本库支持。 在 SPS 中收集的所有生物样本的 12 个月延长跟踪窗口期间的中央存储库 研究并提供生物样本采集套件、样本采集、处理的程序指导、 集中处理和归档支持MAPP-II。 具体目标 2：与 DCC 合作进行样本相关数据收集和跟踪。 将继续与数据协调核心（DCC）密切合作，研究数据收集的最佳实践， 样本跟踪和存储，并支持两个核心之间的技术流程，以及 协调编码、运输、处理、接收、标本储存和转移的程序 生物样本和研究数据存入 NIDDK 中央数据和样本存储库。 具体目标 3：继续参与工作组以及数据分析和手稿 支持 MAPP-RN 的准备工作 我们将继续参与 MAPP 的执行和指导。 我们将继续积极参与 MAPP RN 工作组，以 在想法和假设发展、数据分析和手稿准备方面进行合作。