CELLULAR AND MOLECULAR NEUROSCIENCE CORE

细胞和分子神经科学核心

• 批准号: 7907928
• 负责人: James S Malter
• 金额: $ 33.22万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-01 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7907928
• 关键词: Arts; Computer software; Confocal Microscopy; Cosmetics; DNA Microarray Chip; DNA biosynthesis; Electron Microscopy; Equipment; Flow Cytometry; Fluorescence; Fluorescence Microscopy; Gene Delivery; Genes; Histology; Histopathology; In Vitro; Leadership; Mass Spectrum Analysis; Mental Retardation; Mental Retardation and Developmental Disabilities Research Centers; Microarray Analysis; Molecular; Molecular Genetics; Neurosciences; Pathology; Plasmids; Positioning Attribute; Preparation; Production; Proteomics; Research Personnel; Science; Services; Slide; Technology; Time; Training; Two-Dimensional Gel Electrophoresis; Viral Vector; Wisconsin; cost effective; design; in vivo; new technology

INTRODUCTION The Cellular and Molecular Neuroscience (CMN) Core grew out of the former Pathology, Histology and Stereology (PHS) Core. The new Core reflects a reorganization, refocusing, and expansion of services. The reorganization mirrors a leadership change, with James Malter, MD, assuming the position of Core Director in 2003, along with a change and refocusing in the Core's activities from predominantly morphologic services (e.g., histopathology, slide preparation, and electron microscopy) to those more relevant to contemporary cellular and molecular neuroscience. The expansion of services reflects the addition of new state-of-the-art equipment (e.g., confocal and fluorescence microscopy, flow cytometry, phosphorimaging, and real time PCR) and specialized expertise (e.g., DMA gene arrays, proteomics, and viral vector production). Thus, the new CMN Core is not a cosmetic reshuffling but a true commitment to a host of new services, equipment, and support for the changing needs and composition of the MRDDRC Molecular and Genetic Sciences Group (MGSG)oftheMRDDRC.

介绍 细胞和分子神经科学 (CMN) 核心源于前病理学、组织学和 体视学 (PHS) 核心。新的核心体现了服务的重组、重新定位和扩展。这 重组反映了领导层的变化，医学博士詹姆斯·马尔特 (James Malter) 担任核心董事一职 2003 年，随着核心活动的变化和重新关注，从主要的形态服务 （例如，组织病理学、载玻片制备和电子显微镜）到与当代更相关的知识 细胞和分子神经科学。服务的扩展反映了新的最先进的技术的增加 设备（例如，共聚焦和荧光显微镜、流式细胞仪、磷光成像和实时 PCR） 和专业知识（例如 DMA 基因阵列、蛋白质组学和病毒载体生产）。因此，新的 CMN Core 并不是表面上的重组，而是对一系列新服务、设备和技术的真正承诺。 支持 MRDDRC 分子和遗传科学小组不断变化的需求和组成 MRDDRC 的 (MGSG)。